Comparison of local anaesthetic effects of tramadol with prilocaine for minor surgical procedures (original) (raw)
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Comparison of Local Anesthetic Efficiency of Tramadol Hydrochloride and Lidocaine Hydrochloride
Journal of Oral and Maxillofacial Surgery, 2018
The aim of this study was to investigate the local anesthetic efficiency of tramadol and lidocaine hydrochloride in maxillary infiltration anesthesia. Methods: Our study was a randomized, double-blind study involving 50 healthy volunteers. In the experimental part of this study, two buccal infiltration anesthesias were performed on each volunteer without any treatment. It was performed with tramadol HCL (0.5 mL 25 mg) on one side and 0.5 ml of 20 mg vasoconstrictor-free lidocaine HCL on the other side. After the injections, the total duration of anesthesia, start and finish times of anesthesia, soft tissue (sensory) innervation, depth of anesthetic, possible side effects and satisfaction levels were recorded in all volunteers. Results: There was no significant difference between the two solutions in terms of total anesthesia duration and peak values. However, statistically it was noticed that the effect of lidocaine started and ended early. The efficacy of tramadol was found to be significantly more effective in both gingiva and skin, especially at 15th and 20th minutes compared to lidocaine. It was also observed that both anesthetic agents were well tolerated by volunteers. Conclusion: Tramadol HCL can be a good alternative to local anesthetic anesthetic agents and also thought to be beneficial to support anesthesia during long operations.
Tramadol as an adjuvant to intravenous regional anesthesia with lignocaine
Saudi medical journal, 2008
To assess the effect of different doses of tramadol when added to lignocaine during intravenous regional anesthesia (IVRA). Sixty patients, scheduled for hand surgery under IVRA in King Fahd University Hospital, Al-Khobar, Saudi Arabia from January 2006 to January 2007 were randomly allocated into 3 groups (20 patients each) in a double blind controlled study. All patients received 0.5% lignocaine, 40ml plus 2ml of a study solution containing either isotonic saline control group, or tramadol 50mg (group T50) or tramadol 100 mg (group T100). Hemodynamic changes, sensory and motor block onset and recovery times, tourniquet tolerance time, the quality of intraoperative anesthesia and the duration of postoperative analgesia were assessed. All patients, 20 in each group completed the study period. Patients who received tramadol had earlier onset of sensory block (5.2 +/= 1.2; 4.9 +/= 1.2 min in the T50; and T100 groups) compared with the control group (7.6 +/= 1.4 min). Patients who rece...
2002
Background. Recent studies have shown that a local anaesthetic action of tramadol 5% was able to induce a sensory block to pinprick, touch, and cold similar to that of lidocaine 1%. The aim of this study was to compare the local anaesthetic effects of tramadol hydrochloride with prilocaine. Methods. Sixty ASA I or II patients, undergoing excision of the cutaneous lesions under local anaesthesia, were included in the study. Patients were randomly assigned to receive either 1 ml of tramadol 5% (Group T, n=30) or 1 ml of prilocaine 2% (Group P, n=30) intradermally, in a double-blinded fashion. The degree of the burning sensation and pain at the injection site was documented. Sensory block was assessed 1 min after injection. The patient was asked to report the degree of sensation and to grade touch and pinprick sensation. Two minutes after drug administration, incision was performed and intensity of pain, felt by the patient was evaluated on a four-point scale (0±3). Any local adverse effects were recorded. Results. There was no difference in the quality of block between the two groups. Side effects were noted in both groups with a signi®cant increase in the incidence of local reaction (rash) in Group T (seven patients) when compared with Group P (one patient) (P<0.05). Seven patients in Group T vs four patients in Group P complained of burning at the injection site (P>0.05). Conclusions. Intradermal tramadol 5% can provide a local anaesthesia similar to the prilocaine but the incidence of local adverse effects is higher.
2018
Aims and objectives: To evaluate the efficacy of tramadol as an adjuvant to ropivicaine for intravenous regional anaesthesia(IVRA) and to study the effect of addition of tramadol in respect of onset of sensory blockade, quality of anaesthesia and duration of postoperative analgesia. Introduction: Term ‘VENOUS ANAESTHESIA’ was coined by August Karl Gustav Bier, in 1908 and described an unusual method of producing analgesia of a limb. In this study, we evaluate the efficacy of tramadol as an adjuvant to ropivicaine for IVRA and to study the effect of addition of tramadol in respect of onset of sensory blockade, quality of anaesthesia and duration of postoperative analgesia. Materials and Methods: A total of 24 patients who were planned to undergo upper limb surgeries were divided into two groups. Group A received 40 ml , 0.2% ropivicaine (preservative free) alone. Group B received 40 ml, 0.2% ropivicaine with 100 mg tramadol (preservative free). Assessment of sensory blockade, motor b...
Post-operative effects of tramadol administered at wound closure
European Journal of Anaesthesiology, 1998
group (P<0.001). There were no adverse effects on time to extubation and sedation, and discharge-ready The aim of this prospective, randomized and doubletime was shorter in the tramadol group (P<0.05 comblind study was to assess the effects of a high dose pared with control). Pain scores in the post-anof the analgesic tramadol administered at the conaesthesia care unit (PACU) were statistically not clusion of surgery on extubation time, sedation, and different between the two groups, but significantly post-anaesthetic shivering. Forty adult patients, ASA more supplemental medication was administered in physical status I or II, underwent laparoscopic surgery the control group to treat shivering and/or pain. In of about 1 h duration and received a standardized conclusion, administration of a high dose of tramadol anaesthesia that was maintained with isoflurane in at the end of surgery prevents post-anaesthetic shiv-O 2 /N 2 O. Tramadol 3 mg kg −1 (n=20) was administered ering without prolongation of extubation time, and intravenously at the beginning of wound closure, and shortens the PACU/discharge-ready time. was compared with saline (n=20). Post-anaesthetic shivering did not occur in any patient who received
Acta Veterinaria Brno, 2015
The aim of this study was the evaluation of the practical use of lidocaine/prilocaine cream as the local anaesthetic in combination with tramadol anaesthesia for the surgical treatment of prolapsed penis in chelonians. Eighteen animals were included in this study. After administration of tramadol, prolapsed penis was cleaned and disinfected. Lidocaine/prilocaine cream at a dose of 1g/10 cm2 was applied on the penile mucosa. The time interval from lidocaine/prilocaine application to a loss of hind limb withdrawal reflex and the response to penile mucosa pinching was recorded as the induction time for surgical anaesthesia. The time interval from lidocaine/prilocaine application to full restoration of tail and hind limb withdrawal reflex was recorded as the recovery time. In two male chelonians the response to pain stimuli persisted for more than 20 min after lidocaine/prilocaine cream application, and the anaesthetic cream had to be re-administered. After this second application of li...
Brazilian Journal of Anesthesiology (English Edition), 2015
Background and objectives: Tourniquet pain is one of the major obstacles for intravenous regional anesthesia. We aimed to compare tramadol and lornoxicam used in intravenous regional anesthesia as regards their effects on the quality of anesthesia, tourniquet pain and postoperative pain as well. Methods: After the ethics committee approval 51 patients of ASA physical status I---II aged 18---65 years were enrolled. The patients were divided into three groups. Group P (n = 17) received 3 mg/kg 0.5% prilocaine; group PT (n = 17) 3 mg/kg 0.5% prilocaine + 2 mL (100 mg) tramadol and group PL (n = 17) 3 mg/kg 0.5% prilocaine + 2 mL (8 mg) lornoxicam for intravenous regional anesthesia. Sensory and motor block onset and recovery times were noted, as well as tourniquet pains and postoperative analgesic consumptions. Results: Sensory block onset times in the groups PT and PL were shorter, whereas the corresponding recovery times were longer than those in the group P. Motor block onset times in the groups PT and PL were shorter than that in the group P, whereas recovery time in the group PL was longer than those in the groups P and PT. Tourniquet pain onset time was shortest in the group P and longest in the group PL. There was no difference regarding tourniquet pain among the groups. Group PL displayed the lowest analgesic consumption postoperatively. Conclusion: Adding tramadol and lornoxicam to prilocaine for intravenous regional anesthesia produces favorable effects on sensory and motor blockade. Postoperative analgesic consumption can be decreased by adding tramadol and lornoxicam to prilocaine in intravenous regional anesthesia.