Low levels of 3,3′-diindolylmethane activate estrogen receptor α and induce proliferation of breast cancer cells in the absence of estradiol
Luc Gaudreau
BMC Cancer, 2014
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2,3,7,8-Tetrachlorodibenzo-p-dioxin and Diindolylmethanes Differentially Induce Cytochrome P450 1A1, 1B1, and 19 in H295R Human Adrenocortical Carcinoma Cells
Lennert Slobbe
Toxicological Sciences, 2001
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Inhibition of estradiol-induced mammary proliferation by dibenzoylmethane through the E2-ER-ERE-dependent pathway
Yao-ping Lu
Carcinogenesis, 2005
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Blocking Epidermal Growth Factor Receptor Activation by 3,3'-Diindolylmethane Suppresses Ovarian Tumor Growth In Vitro and In Vivo
prabodh kandala
Journal of Pharmacology and Experimental Therapeutics, 2012
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Estradiol enhances and estriol inhibits the expression of CYP1A1 induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in a mouse ovarian cancer cell line
P. Terranova, Deok-soo Son
Toxicology, 2002
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The biological evaluation of novel antioestrogens for the treatment of breast cancer
Yunus Luqmani
Critical Reviews in Oncology/Hematology, 1993
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Prevention and Treatment of Experimental Estrogen Receptor-Negative Mammary Carcinogenesis by the Synthetic Triterpenoid CDDO-Methyl Ester and the Rexinoid LG100268
Gordon Gribble
Clinical Cancer Research, 2008
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3,3'-Diindolylmethane and genistein decrease the adverse effects of estrogen in LNCaP and PC-3 prostate cancer cells
Sunyata Smith
The Journal of Nutrition, 2008
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Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer
Anupam Bishayee
International Journal of Cancer, 2013
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The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy
Craig Rowlands
Endocrine-Related Cancer, 2009
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Interplay of genes regulated by estrogen and diindolylmethane in breast cancer cell lines
Alamelu Chandrasekaran
Molecular medicine (Cambridge, Mass.)
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Aryl hydrocarbon receptor agonists directly activate estrogen receptor α in MCF-7 breast cancer cells
Eric Ariazi
Biological Chemistry, 2006
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Role of Estradiol Receptor-α in Differential Expression of 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Inducible Genes in the RL95-2 and KLE Human Endometrial Cancer Cell Lines
Hideko Sone
Archives of Biochemistry and Biophysics, 1999
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The inhibitory effect of 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) on estrogen-dependent mammary tumors
Martin Berger
European journal of cancer & clinical oncology, 1985
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Selective Activation of Estrogen Receptor-β Target Genes by 3,3′-Diindolylmethane
Aleksandra Cvoro
Endocrinology, 2010
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Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors α- and β-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft
Vishal Chandra
Steroids, 2013
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Down-regulation of Androgen Receptor by 3,3'-Diindolylmethane Contributes to Inhibition of Cell Proliferation and Induction of Apoptosis in Both Hormone-Sensitive LNCaP and Insensitive C4-2B Prostate Cancer Cells
Mohammad Bhuiyan
Cancer Research, 2006
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The Ah receptor inhibits estrogen-induced estrogen receptor � in breast cancer cells
Katarina Pettersson
Biochem Biophys Res Commun, 2004
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A New Antiestrogen, 2-(4-Hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1H-indol-5-ol hydrochloride (ERA-923), Inhibits the Growth of Tamoxifen-sensitive and -resistant Tumors and Is Devoid of Uterotropic Effects in Mice and Rats
Tami Annable
Clinical Cancer Research, 2001
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In Vivo Assessment of Anti-Tumor Activity of Methyl 2'-Methyl-1,3-dioxo-1,1',2',3,5',6',7',7a'-octahydrospiro[indene-2,3'-pyrrolizidine]-2' carboxylate (6) on 7,12 dimethylbenz(a) Anthracene-Induced Mammary Tumors in Rat
Leila Zarei
Iranian Journal of Veterinary Surgery, 2017
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3′, 4′-Dimethoxyflavone as an aryl hydrocarbon receptor antagonist in human breast cancer cells
S. Safe
Toxicological Sciences, 2000
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Studies on the Relationship between Estrogen Receptor Content, GlutathioneS-Transferase π Expression, and Induction by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Drug Resistance in Human Breast Cancer Cells
R. Burghardt
Archives of Biochemistry and Biophysics, 1997
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Inhibition of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor growth by aryl hydrocarbon receptor agonists
Tin Khor
Cancer Letters, 1997
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1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE) disrupts the estrogen-androgen balance regulating the growth of hormone-dependent breast cancer cells
Christian Larochelle
Breast Cancer Research, 2008
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Remarks in Successful Cellular Investigations for Fighting Breast Cancer Using Novel Synthetic Compounds
Maryam Nakhjavani
Breast Cancer - Focusing Tumor Microenvironment, Stem cells and Metastasis, 2011
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Antiestrogenic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Are Mediated by Direct Transcriptional Interference with the Liganded Estrogen Receptor
Paul Cooke
Journal of Biological Chemistry, 1996
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Ah receptor agonists as endocrine disruptors: antiestrogenic activity and mechanisms
S. Safe
Toxicology Letters, 1998
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A novel naphthalimide that selectively targets breast cancer via the arylhydrocarbon receptor pathway
Jennette Sakoff
Scientific Reports
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Effects of 7-O Substitutions on Estrogenic and Anti-Estrogenic Activities of Daidzein Analogues in MCF-7 Breast Cancer Cells
john mclachlan
Journal of Medicinal Chemistry, 2010
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