GENETIC ANALYSIS OF THE ACTIVE SITES OF lac REPRESSOR (original) (raw)

Genetic Studies of the Lac Repressor XV: 4000 Single Amino Acid Substitutions and Analysis of the Resulting Phenotypes on the Basis of the Protein Structure

Pete Markiewicz

Journal of Molecular Biology, 1996

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Genetic studies of the lac repressor. VII. On the molecular nature of spontaneous hotspots in the …

P. Farabaugh

Journal of molecular biology

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Lac repressor genetic map in real space

Jeffrey Miller

Trends in Biochemical Sciences, 1997

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Evidence for a contact between glutamine-18 of lac repressor and base pair 7 of lac operator

Richard Ebright

Proceedings of the National Academy of Sciences, 1986

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An amino-terminal fragment of lac repressor binds specifically to lac operator

W. Gilbert

Proceedings of the National Academy of Sciences, 1978

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Thermodynamic analysis of mutant lac repressors

Mitchell Lewis

2011

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LAC REPRESSOR: A genetic and nuclear magnetic resonance study of structure and function

Ponzy Lu

Biophysical Journal, 1980

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Use of lac regulatory elements for gene expression in Lactobacillus casei

luis rosaldo

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Analysis of inducers of the E.coli lac repressor system mammalian cells and whole animals

Jay Short

Nucleic Acids Research, 1991

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Perturbation from a Distance: Mutations that Alter LacI Function through Long-Range Effects †

Hongli Zhan

Biochemistry, 2003

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A single mutation in the core domain of the lac repressor reduces leakiness

Sean Devenish, Willem Dijkman

Microbial Cell Factories, 2013

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CHAPTER 17 JACOB/MONOD: HOW THE REPRESSOR PROTEIN CONTROLS THE lac

naga jogayya

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Escherichia coli lac repressor-lac operator interaction and the influence of allosteric effectors

Ponzy Lu

Journal of Molecular Biology, 1997

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Studies on gene control regions. III. Binding of synthetic and modified synthetic lac operator DNAs to lactose repressor

David Cribbs

Nucleic Acids Research, 1977

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Altered Specificity in DNA Binding by the lac Repressor: A Mutant lac Headpiece that Mimics the gal Repressor

Roberto Salinas

ChemBioChem, 2005

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How lac repressor recognizes lac operator

D. Yansura

Proceedings of the National Academy of Sciences, 1978

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Studies on gene control regions X. The effect of specific adenine-thymine transversions on the lac repressor-lac operator interaction

Randall Loder

Nucleic Acids Research, 1979

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Studies on gene control regions. VI. The 5- methyl of thymine, a lac repressor recognition site

D. Yansura

Nucleic Acids Research, 1977

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Targeted mutagenesis in vitro: lac repressor mutations generated-using AMV reverse transcriptase and dBrUTP

John Mott

Nucleic Acids Research, 1984

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Regulation of lac operon expression: reappraisal of the theory of catabolite repression

Barry Wanner

Journal of bacteriology, 1978

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Lac repressor purification without inactivation of DNA binding activity

John Rosenberg

Nucleic Acids Research, 1977

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Activity of Lac repressor anchored to the Escherichia coli inner membrane

Bodo Rak

Nucleic Acids Research, 2005

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A quantitative understanding of lac repressor’s binding specificity and flexibility

Gary Stormo

Quantitative Biology, 2015

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The lac operator is DNA

W. Gilbert

Proceedings of the National Academy of Sciences, 1967

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Subdividing Repressor Function: DNA Binding Affinity, Selectivity, and Allostery Can Be Altered by Amino Acid Substitution of Nonconserved Residues in a LacI/GalR Homologue †

Hongli Zhan

Biochemistry, 2008

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Missense mutation in the lacI gene of Escherichia coli

Michael Horsfall

Journal of Molecular Biology, 1988

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Regulation of lac Operon Expression: Reappraisal of the Theory of Catabolite Repression

Barry Wanner

Journal of Bacteriology, 1978

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Suppression of and complementation among mutants of the regulatory gene of the lactose operon of Escherichia coli

Melvin Cohn

Journal of Molecular Biology, 1965

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Lac repressor—operator complex

Ponzy Lu

Current Opinion in Structural Biology, 1997

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Structural Analysis of Lac Repressor Bound to Allosteric Effectors

Steven Stayrook

Journal of Molecular Biology, 2007

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High-Resolution Specificity from DNA Sequencing Highlights Alternative Modes of Lac Repressor Binding

Gary Stormo

Genetics, 2014

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Molecular parameters characterizing the interaction of Escherichia coli lac repressor with non-operator DNA and inducer

Peter Von Hipel

Biochemistry, 1977

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Physiological regulation of a decontrolled lac operon

Barry Wanner

Journal of bacteriology, 1977

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Modifications of theE.coliLac repressor for expression in eukaryotic cells: effects of nuclear signal sequences on protein activity and nuclear accumulation

Jay M Short

Nucleic Acids Research, 1992

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The lactose repressor system: paradigms for regulation, allosteric behavior and protein folding

Hongli Zhan

Cellular and Molecular Life Sciences, 2007

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