Thermodynamic analysis of mutant lac repressors (original) (raw)
The lactose repressor system: paradigms for regulation, allosteric behavior and protein folding
Hongli Zhan
Cellular and Molecular Life Sciences, 2007
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Escherichia coli lac repressor-lac operator interaction and the influence of allosteric effectors
Ponzy Lu
Journal of Molecular Biology, 1997
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Structural Analysis of Lac Repressor Bound to Allosteric Effectors
Steven Stayrook
Journal of Molecular Biology, 2007
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Positions 94−98 of the Lactose Repressor N-Subdomain Monomer−Monomer Interface Are Critical for Allosteric Communication
Hongli Zhan
Biochemistry, 2010
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A single mutation in the core domain of the lac repressor reduces leakiness
Sean Devenish, Willem Dijkman
Microbial Cell Factories, 2013
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A quantitative understanding of lac repressor’s binding specificity and flexibility
Gary Stormo
Quantitative Biology, 2015
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Lac repressor genetic map in real space
Jeffrey Miller
Trends in Biochemical Sciences, 1997
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Subdividing Repressor Function: DNA Binding Affinity, Selectivity, and Allostery Can Be Altered by Amino Acid Substitution of Nonconserved Residues in a LacI/GalR Homologue †
Hongli Zhan
Biochemistry, 2008
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Perturbation from a Distance: Mutations that Alter LacI Function through Long-Range Effects †
Hongli Zhan
Biochemistry, 2003
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Molecular parameters characterizing the interaction of Escherichia coli lac repressor with non-operator DNA and inducer
Peter Von Hipel
Biochemistry, 1977
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CHAPTER 17 JACOB/MONOD: HOW THE REPRESSOR PROTEIN CONTROLS THE lac
naga jogayya
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Ligand interactions with lactose repressor protein and the repressor-operator complex: The effects of ionization and oligomerization on binding
Hongli Zhan
Biophysical Chemistry, 2007
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Studies on gene control regions. III. Binding of synthetic and modified synthetic lac operator DNAs to lactose repressor
David Cribbs
Nucleic Acids Research, 1977
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Binding of synthetic lactose operator DNAs to lactose repressors
D. Yansura
Proceedings of the National Academy of Sciences, 1977
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The effect of LacI autoregulation on the performance of the lactose utilization system in Escherichia coli
Szabolcs Semsey
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Thermodynamic mechanism for inhibition of lactose permease by the phosphotransferase protein IIAGlc
Alan Peterkofsky
Proceedings of the National Academy of Sciences of the United States of America, 2015
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Altered Specificity in DNA Binding by the lac Repressor: A Mutant lac Headpiece that Mimics the gal Repressor
Roberto Salinas
ChemBioChem, 2005
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Inducible gene expression mediated by a repressor-operator system isolated from Lactococcus lactis bacteriophage r1t
Douwe Van Sinderen
Molecular Microbiology, 1996
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“Multiplex” rheostat positions cluster around allosterically critical regions of the lactose repressor protein
Daniel Parente
2020
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Heat Resistance and Salt Hypersensitivity in Lactococcus lactis Due to Spontaneous Mutation of llmg_1816 (gdpP) Induced by High-Temperature Growth
Aijaz Soomro
Applied and Environmental Microbiology, 2012
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Ligand-induced Conformational Changes and Conformational Dynamics in the Solution Structure of the Lactose Repressor Protein
Hongli Zhan
Journal of Molecular Biology, 2008
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GENETIC ANALYSIS OF THE ACTIVE SITES OF lac REPRESSOR
Bruno Gronenborn
Genetics, 1974
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Suppression of and complementation among mutants of the regulatory gene of the lactose operon of Escherichia coli
Melvin Cohn
Journal of Molecular Biology, 1965
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Activity of Lac repressor anchored to the Escherichia coli inner membrane
Bodo Rak
Nucleic Acids Research, 2005
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Repressor-operator interaction in the lac operon
Harry Nick
Journal of Molecular Biology, 1982
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Coregulation of the Kluyveromyces lactis lactose permease and β-galactoidase genes is achieved by interaction of multiple LAC9 binding sites in a 2.6 kbp divergnent promoter
Karin Breunig
Nucleic Acids Research, 1991
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Represser-operator interaction in the lac operon
Ponzy Lu
Journal of Molecular Biology, 1982
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Bistable behavior of the lac operon in E. coli when induced with a mixture of lactose and TMG
Moisés Santillán
Frontiers in physiology, 2010
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Ligand-Induced Conformational Changes in Lactose Repressor: A Phosphorescence and ODMR Study of Single-Tryptophan Mutants †
John C Voss
Biochemistry, 1999
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Topology of allosteric regulation of lactose permease
Alan Peterkofsky
Proceedings of the National Academy of Sciences, 1997
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Evidence for a contact between glutamine-18 of lac repressor and base pair 7 of lac operator
Richard Ebright
Proceedings of the National Academy of Sciences, 1986
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Genetic Studies of the Lac Repressor XV: 4000 Single Amino Acid Substitutions and Analysis of the Resulting Phenotypes on the Basis of the Protein Structure
Pete Markiewicz
Journal of Molecular Biology, 1996
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A family of bacterial regulators homologous to Gal and Lac repressors
S. Adhya
Journal of Biological Chemistry, 1992
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Influence of DNA structure on the lactose operator-repressor interaction
Hardy W. Chan
Biochemistry, 1977
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The lac Repressor Protein: Molecular Shape, Subunit Structure, and Proposed Model for Operator Interaction Based on Structural Studies of Microcrystals
Donald Engelman
Proceedings of the National Academy of Sciences, 1974
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