Study of the most important physiologic parameter using GSA with sobol method and a PBPK model for individualization of peptide-receptor radionuclide therapy (original ) (raw )A stylized computational model of the rat for organ dosimetry in support of preclinical evaluations of peptide receptor radionuclide therapy with (90)Y, (111)In, or (177)Lu
Mark Konijnenberg
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004
View PDFchevron_right
Sensitivity Analysis of a Physiologically Based Pharmacokinetic Model Used for Treatment Planning in Peptide Receptor Radionuclide Therapy
Felix Mottaghy
Cancer Biotherapy and Radiopharmaceuticals, 2016
View PDFchevron_right
Generalized paired-agent kinetic model forin vivoquantification of cancer cell-surface receptors under receptor saturation conditions
Negar Sadeghipour
Physics in Medicine and Biology, 2016
View PDFchevron_right
Differences in predicted and actually absorbed doses in peptide receptor radionuclide therapy
Felix Mottaghy
Medical Physics, 2012
View PDFchevron_right
Dependence of treatment planning accuracy in peptide receptor radionuclide therapy on the sampling schedule
Felix Mottaghy
EJNMMI Research, 2016
View PDFchevron_right
Compartmental Analysis to Predict Biodistribution In Radiopharmaceutical Design Studies
Carlos Mesquita
2002
View PDFchevron_right
The biological effectiveness of targeted radionuclide therapy based on a whole-body pharmacokinetic model
Wolfgang A Tomé
Physics in Medicine and Biology, 2010
View PDFchevron_right
Dosimetric Evaluation of the Effect of Receptor Heterogeneity on the Therapeutic Efficacy of Peptide Receptor Radionuclide Therapy: Correlation with DNA Damage Induction and In Vivo Survival
L. Struelens
Journal of Nuclear Medicine, 2021
View PDFchevron_right
Dosimetric evaluation of receptor-heterogeneity on the therapeutic efficacy of peptide receptor radionuclide therapy: correlation with DNA damage induction and in vivo survival
Mark Konijnenberg
Journal of Nuclear Medicine
View PDFchevron_right
A population-based method to determine the time-integrated activity in molecular radiotherapy
Ade Riana
EJNMMI Physics, 2021
View PDFchevron_right
Model-Based Evaluation of Radiation and Radiosensitizing Agents in Oncology
Mats Jirstrand
CPT: Pharmacometrics & Systems Pharmacology
View PDFchevron_right
Study the effect of the physiological parameters to the optimal administration of lysine/arginine during peptide receptor radionuclide therapy (PPRT) using a physiologically-based pharmacokinetic (PBPK) model
M Luthfy
PROCEEDINGS OF THE INTERNATIONAL CONFERENCE AND SCHOOL ON PHYSICS IN MEDICINE AND BIOSYSTEM (ICSPMB): Physics Contribution in Medicine and Biomedical Applications
View PDFchevron_right
Mechanistically weighted metric to predictin vivo antibody-receptor occupancy: An analytical approach
Greg Thurber
Journal of Pharmacology and Experimental Therapeutics, 2023
View PDFchevron_right
Prediction of time-integrated activity coefficients in PRRT using simulated dynamic PET and a pharmacokinetic model
Felix Mottaghy
Physica Medica, 2017
View PDFchevron_right
Dosimetry in Peptide radionuclide receptor therapy: a review
Marta Cremonesi
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006
View PDFchevron_right
Comparison of kinetic models for dual-tracer receptor concentration imaging in tumors
Tayyaba Hasan
View PDFchevron_right
The use of in vitro models to predict the distribution of receptor binding radiotracers in vivo
William Eckelman
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1989
View PDFchevron_right
Tumour control probability derived from dose distribution in homogeneous and heterogeneous models: assuming similar pharmacokinetics, 125 Sn– 177 Lu is superior to 90 Y– 177 Lu in peptide receptor radiotherapy
François Jamar
Physics in Medicine and Biology, 2012
View PDFchevron_right
Dose-incidence modeling: consequences of linking quantal measures of response to depletion of critical tissue targets
Melvin Andersen
Toxicological sciences : an official journal of the Society of Toxicology, 2006
View PDFchevron_right
Time-integrated activity coefficient estimation for radionuclide therapy using PET and a pharmacokinetic model: A simulation study on the effect of sampling schedule and noise
Felix Mottaghy
Medical Physics, 2016
View PDFchevron_right
Personalized 177Lu-octreotate peptide receptor radionuclide therapy of neuroendocrine tumours: a simulation study
Francois-Alexandre Buteau
European Journal of Nuclear Medicine and Molecular Imaging, 2017
View PDFchevron_right
Advantages of a dual-tracer model over reference tissue models for binding potential measurement in tumors
Kenneth Tichauer , Tayaba Hasan
Physics in Medicine and Biology, 2012
View PDFchevron_right
A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Monica Celli
Journal of Visualized Experiments
View PDFchevron_right
Simple model for estimation of absorbed dose by organs and tumors after PRRT from a single SPECT/CT study
Amichay Meirovitz
EJNMMI Physics
View PDFchevron_right
The analysis of dose-response curves-a practical approach
Atholl Johnston
British Journal of Clinical Pharmacology, 1987
View PDFchevron_right
Dose Point Kernel calculation and modeling with nuclear medicine dosimetry purposes
Pedro Alejandro Mendoza Pérez
Proceedings of 10th Latin American Symposium on Nuclear Physics and Applications — PoS(X LASNPA), 2014
View PDFchevron_right
Dose Point Kernel calculation and modelling with nuclear medicine dosimetry purposes
Mauro Valente
View PDFchevron_right
{"__content__"=>"Correlation of dose with toxicity and tumour response to Y- and Lu-PRRT provides the basis for optimization through individualized treatment planning.", "sup"=>[{"__content__"=>"90"}, {"__content__"=>"177"}]}
Anna Sarnelli
European journal of nuclear medicine and molecular imaging, 2018
View PDFchevron_right
Use of the proportionality equations for analyses of dose–response curves
Ralph Lai
Pharmacological Research, 2003
View PDFchevron_right
Single-Time-Point Dosimetry Using Model Selection and Non-Linear Mixed-Effects Modelling
Ade Riana
Research Square (Research Square), 2022
View PDFchevron_right
Calculation of absorbed dose due to the 90Y-DOTATOC peptide receptor radionuclide therapy by MCNP5/X
Dragoslav Nikezic
Nuclear Technology and Radiation Protection, 2018
View PDFchevron_right
Patient specific dosimetric calculations obtained by planar images and Monte Carlo simulation in 111In octreotide therapy
Nefeli Lagopati
Case Reports and Images in Surgery, 2018
View PDFchevron_right