Are apolipoprotein E fragments a promising new therapeutic target for Alzheimer’s disease? (original) (raw)

The Role of Apolipoprotein E in Alzheimer's Disease

Jungsu Kim

Neuron, 2009

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Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology

Larry Baum

Microscopy Research and Technique, 2000

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Apolipoprotein E in Alzheimer's disease and other neurological disorders

Philip Verghese

The Lancet Neurology, 2011

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Opposite Roles of Apolipoprotein E in Normal Brains and in Alzheimer's Disease

claudio russo

Proceedings of The National Academy of Sciences, 1998

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Function and Comorbidities of Apolipoprotein E in Alzheimer's Disease

Judes Poirier

International Journal of Alzheimer's Disease, 2011

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Apolipoprotein E, Amyloid, and Alzheimer Disease

JC Dodart

Molecular Interventions, 2002

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Apolipoprotein E and Alzheimer's disease: The protective effects of ApoE2 and E3

M. Kindy

Journal of Alzheimer's Disease, 2002

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Apolipoprotein E metabolism and functions in brain and its role in Alzheimerʼs disease

Fan Liao

Current Opinion in Lipidology, 2016

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Apolipoprotein E represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer’s disease

Judes Poirier

Alzheimer's & Dementia, 2008

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Apolipoprotein E and Alzheimer disease: an update on genetic and functional analyses

Ann Saunders

Journal of neuropathology and experimental neurology, 2000

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The role of apolipoprotein E in Alzheimer’s disease: pharmacogenomic target selection

Karen Horsburgh

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2000

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Apolipoprotein e: essential catalyst of the Alzheimer amyloid cascade

Huntington Potter

International journal of Alzheimer's disease, 2012

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Apolipoprotein E and Alzheimer's disease: the implications of progress in molecular medicine

Nicole Schupf

American Journal of Public Health, 1995

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Molecular pathogenesis of apolipoprotein E-mediated amyloidosis in late-onset Alzheimer's disease

Elizabeth Corder

Cellular and Molecular Life Sciences (CMLS), 1999

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Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

Robert Mahley

Neurobiology of disease, 2014

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Apolipoprotein E as a β-amyloid-independent factor in Alzheimer’s disease

Jungsu Kim

Alzheimer's Research & Therapy, 2013

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Apolipoprotein E and Lipid Homeostasis in the Etiology and Treatment of Sporadic Alzheimer’s disease

Cynthia Picard

Neurobiology of Aging, 2014

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ApoE in Alzheimer’s disease: pathophysiology and therapeutic strategies

Zachary Trottier

Molecular Neurodegeneration

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Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer’s amyloid β peptides

ruben vidal

Biochemical Journal, 2000

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Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease

Judes Poirier

Trends in Molecular Medicine, 2003

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Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study

Marc Cruts

Neuroscience Letters, 1998

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Apolipoprotein E (apoE) levels in brains from Alzheimer disease patients and controls

Nenad Bogdanovic, Terho Lehtimäki

Brain Research, 1996

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Epidemiological, Clinical, and Neuropathological Study of Apolipoprotein E Genotype in Alzheimer's Disease

Howard West

Annals of the New York Academy of Sciences, 1996

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Association of human, rat, and rabbit apolipoprotein E with β‐amyloid

Godfrey Getz

Journal of Neuroscience Research, 1997

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Current knowledge on the relationship between ApoE and Alzheimer’s disease

Myrthe aan de Stegge

2018

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Apolipoprotein E Isoforms Differentially Regulate Alzheimer's Disease and Amyloid-β-Induced Inflammatory Response in vivo and in vitro

danica stanimirovic

Journal of Alzheimer's disease : JAD, 2017

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Binding of Human Apolipoprotein E to Synthetic Amyloid Beta Peptide: Isoform-Specific Effects and Implications for Late-Onset Alzheimer Disease

Dong Li

Proceedings of the …, 1993

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Quantification of total apolipoprotein E and its specific isoforms in cerebrospinal fluid and blood in Alzheimer’s disease and other neurodegenerative diseases

Ann Brinkmalm

EuPA Open Proteomics, 2015

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ApoE Lipidation as a Therapeutic Target in Alzheimer’s Disease

Christi Anne Ng

2020

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Apolipoprotein (apo) E4 enhances amyloid peptide production in cultured neuronal cells: ApoE structure as a potential therapeutic target

Elaine Meng, Irwin Kuntz

Proceedings of the National Academy of Sciences, 2005

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Role of apolipoprotein E in neurodegenerative diseases

Seong An

Neuropsychiatric Disease and Treatment, 2015

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