Opposite Roles of Apolipoprotein E in Normal Brains and in Alzheimer's Disease (original) (raw)

Association of human, rat, and rabbit apolipoprotein E with β‐amyloid

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Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer’s amyloid β peptides

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Characterization of stable complexes involving apolipoprotein E and the amyloid β peptide in Alzheimer's disease brain

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Specific Modulation of the Fusogenic Properties of the Alzheimer beta-Amyloid Peptide by Apolipoprotein E Isoforms

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Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology

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Human Cerebrospinal Fluid Apolipoprotein E Isoforms are Apparently Inefficient at Complexing with Synthetic Alzheimer’s Amyloid-β Peptide (Aß1−40) in vitro

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Molecular Medicine, 2002

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Apolipoprotein E and β-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent

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Apolipoprotein E (apoE) levels in brains from Alzheimer disease patients and controls

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Binding of Human Apolipoprotein E to Synthetic Amyloid Beta Peptide: Isoform-Specific Effects and Implications for Late-Onset Alzheimer Disease

Dong Li

Proceedings of the …, 1993

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The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific

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Isoform-Specific Effects of Apolipoproteins E2, E3, and E4 on Cerebral Capillary Sequestration and Blood-Brain Barrier Transport of Circulating Alzheimer's Amyloid β

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Journal of Neurochemistry, 2002

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Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer’s disease patients

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The Role of Apolipoprotein E in Alzheimer's Disease

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Are apolipoprotein E fragments a promising new therapeutic target for Alzheimer’s disease?

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Molecular pathogenesis of apolipoprotein E-mediated amyloidosis in late-onset Alzheimer's disease

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Apolipoprotein e: essential catalyst of the Alzheimer amyloid cascade

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International journal of Alzheimer's disease, 2012

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Expression of human apolipoprotein E reduces amyloid-β deposition in a mouse model of Alzheimer's disease

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Journal of Clinical Investigation, 1999

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Apolipoprotein E is essential for amyloid deposition in the APPV717F transgenic mouse model of Alzheimer's disease

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Proceedings of the National Academy of Sciences, 1999

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Apolipoprotein-E modulates the cytotoxic effect of β-amyloid on rat brain endothelium in an isoform-dependent specific manner

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International Journal of Molecular Medicine, 2006

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An apolipoprotein E4 fragment can promote intracellular accumulation of amyloid peptide beta 42

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Journal of …, 2010

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Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer’s disease

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Apolipoprotein E as a β-amyloid-independent factor in Alzheimer’s disease

Jungsu Kim

Alzheimer's Research & Therapy, 2013

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β-Amyloid Peptides Increase the Binding and Internalization of Apolipoprotein E to Hippocampal Neurons

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Journal of Neurochemistry, 2002

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