Past, present and future of A2A adenosine receptor antagonists in the therapy of Parkinson's disease (original) (raw)

An Update on Adenosine A2A Receptors as Drug Target in Parkinson's Disease

luisa Arna

CNS & Neurological Disorders - Drug Targets, 2011

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New therapies for the treatment of Parkinson's disease: Adenosine A2A receptor antagonists

Jadwiga Wardas

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Targeting adenosine A 2A receptors in Parkinson's disease

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Dopamine and adenosine receptor interaction as basis for the treatment of Parkinson's disease

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Journal of The Neurological Sciences, 2006

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Adenosine A 2A receptors, dopamine D 2 receptors and their interactions in Parkinson's disease

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Movement Disorders, 2007

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Adenosine A2A receptor antagonists: Potential therapeutic and neuroprotective effects in parkinson’s disease

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Targeting Adenosine Signaling in Parkinson's Disease: From Pharmacological to Non-pharmacological Approaches

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Role of adenosine A2A receptors in parkinsonian motor impairment and l-DOPA-induced motor complications

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Adenosine A2Areceptor antagonist treatment of Parkinson’s disease

Francesco Bibbiani

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Adenosine A2A-Receptor Antagonism and Pathophysiology of Parkinson’s Disease and Drug-Induced Movement Disorders

Jaime Kulisevsky

European Neurology, 2012

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Adenosine/dopamine interaction: implications for the treatment of Parkinson's disease

Roberto Rimondini

Parkinsonism & Related Disorders, 2001

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Blocking Striatal Adenosine A2A Receptors: A New Strategy for Basal Ganglia Disorders

Christa Mueller

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Adenosine A 2A Receptor Antagonists: New 8-Substituted 9-Ethyladenines as Tools for in vivo Rat Models of Parkinson's Disease

Catia Lambertucci

ChemMedChem, 2009

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Adenosine A2A Antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in Parkinsonian monkeys

Ronald Pearce

Annals of Neurology, 1998

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Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats

Rafael Lujan

Disease Models & Mechanisms, 2014

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Receptor heteromerization in adenosine A2A receptor signaling Relevance for striatal function and Parkinson's disease

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Untangling dopamine-adenosine receptor assembly in experimental parkinsonism

Francisco Ciruela

Disease Models & Mechanisms, 2014

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ST 1535: a preferential A2A adenosine receptor antagonist

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The International Journal of Neuropsychopharmacology, 2005

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Dopamine D2 receptor-mediated modulation of adenosine A2A receptor agonist binding within the A2AR/D2R oligomer framework

Martha Soler

Neurochemistry International, 2013

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Adenosine Receptors as a Paradigm to Identify Dimer/Oligomers of G-Protein-Coupled Receptors and as Targets in Parkinson’s Disease and Schizophrenia

Gemma Navarro

Springer eBooks, 2018

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Functional impact of the G279S substitution in the adenosine A1-receptor (A1R-G279S), a mutation associated with Parkinson's disease

Michael Freissmuth

Molecular Pharmacology, 2020

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Adenosine A2A agonist CGS 21680 decreases the affinity of dopamine D2 receptors for dopamine in human striatum

Michele Zoli

Neuroreport, 2001

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A Double-Blind Crossover, Placebo-Controlled Study of the Adenosine A2A Antagonist Theophylline in Parkinson's Disease

Miquel Casas

Clinical Neuropharmacology, 2002

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Adenosine 2A receptor availability in dyskinetic and nondyskinetic patients with Parkinson disease

Imtiaz Ahmed

Neurology, 2011

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A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer

Elisa Nuti

Cellular Signalling, 2012

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Discovery of nonxanthine adenosine A 2A receptor antagonists for the treatment of Parkinson's disease

Colin T Dourish

Neurology, 2003

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Distribution, biochemistry and function of striatal adenosine A2A receptors

G. Fisone

Progress in neurobiology, 1999

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