Distinct focal adhesion protein modules control different aspects of mechanotransduction (original) (raw)

Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair

jeroen eyckmans

Nature Communications, 2021

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Mechanotransduction and focal adhesions

Wolfgang Goldmann

Cell Biology International, 2012

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Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

Maddy Parsons

Nature, 2010

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Retrograde Fluxes of Focal Adhesion Proteins in Response to Cell Migration and Mechanical Signals

Yu-li Wang

Molecular Biology of the Cell, 2007

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Force-dependent vinculin binding to talin in live cells: a crucial step in anchoring the actin cytoskeleton to focal adhesions

Masahiro Sokabe

American Journal of Physiology-Cell Physiology, 2014

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Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

Christoph Ballestrem

Current Biology, 2013

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Tyrosine phosphorylation of vinculin at position 1065 modifies focal adhesion dynamics and cell tractions

Wolfgang Goldmann, Norbert Kirchgeßner

Biochemical and Biophysical Research Communications, 2010

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Contractility modulates cell adhesion strengthening through focal adhesion kinase and assembly of vinculin-containing focal adhesions

ANDRES GARCIA

Journal of Cellular Physiology, 2010

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Monitoring in real-time focal adhesion protein dynamics in response to a discrete mechanical stimulus

Andrea Bragas

Review of Scientific Instruments

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CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics

Radoslav Janoštiak

Cellular and Molecular Life Sciences, 2014

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Molecular Mechanisms of Mechanosensitivity in Focal Adhesions

Hengameh Shams

2016

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Force-induced activation of Talin and its possible role in focal adhesion mechanotransduction

Roger D. Kamm

Journal of Biomechanics, 2007

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Focal Adhesions: A Nexus for Intracellular Signaling and Cytoskeletal Dynamics

Keith Burridge

Experimental Cell Research, 2000

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Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells

Sanjay Kumar

Journal of Cellular Physiology, 2006

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The role of mechanical stretching in the activation and localization of adhesion proteins and related intracellular molecules

Michela Bosetti

Journal of Cellular Biochemistry, 2011

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Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

Clare Waterman

Cell, 2012

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Assembly and mechanosensory function of focal adhesions: experiments and models

Alexander Verkhovsky, Christoph Ballestrem

European Journal of Cell Biology, 2006

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Actomyosin-generated tension controls the molecular kinetics of focal adhesions

Alexander Bershadsky

Journal of Cell Science, 2011

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Force meets chemistry: Analysis of mechanochemical conversion in focal adhesions using fluorescence recovery after photobleaching

Donald Ingber

Journal of Cellular Biochemistry, 2006

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Vinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesions

Keith Burridge

The Journal of Cell Biology, 2014

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Adhesion-Dependent Cell Mechanosensitivity

Alexander Bershadsky

Annual Review of Cell and Developmental Biology, 2003

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Formation of talin-vinculin pre-complexes dictates maturation of nascent adhesions by accelerated force transmission and vinculin recruitment

Kevin Dean

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The focal adhesion protein talin is a mechanically gated A-kinase anchoring protein

Alan Howe, Ben Goult

PNAS, 2024

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Crosstalk between focal adhesions and material mechanical properties governs cell mechanics and functions

valeria panzetta

Acta Biomaterialia, 2015

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Integrating actin dynamics, mechanotransduction and integrin activation: The multiple functions of actin binding proteins in focal adhesions

Corina Ciobanasu, Christophe Le Clainche

European Journal of Cell Biology, 2013

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Modeling of Mechanosensing Mechanisms Reveals Distinct Cell Migration Modes to Emerge From Combinations of Substrate Stiffness and Adhesion Receptor-Ligand Affinity

Diego Vargas

Frontiers in Bioengineering and Biotechnology, 2020

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Effects of mechanical stress on cell adhesion A possible mechanism for morphological changes

M. Bosetti

2010

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Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions

Sharon Campbell

Nature Cell Biology, 2015

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Identification of an Actin Binding Surface on Vinculin that Mediates Mechanical Cell and Focal Adhesion Properties

Keith Burridge

Structure, 2014

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The focal adhesion targeting (FAT) domain of p130 Crk associated substrate (p130Cas) confers mechanosensing function

Shiloh Middlemiss

Journal of cell science, 2017

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