An audit of the clinicopathological spectrum of benign vascular tumors of female genital tract; with a mini narrative review (original) (raw)

Vulval angiomyxoma: a case report

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Aggressive angiomyxoma is a rare, locally invasive mesenchymal tumor occurring usually in women of reproductive age, which carries a high risk for local relapse; hence it needs to be differentiated from other mesenchymal tumors occurring in this region. We describe a case of a 39-year-old female presenting with a large swelling on the left labia majora. Initially she presented as a small mass over left labia majora 2 years ago from which biopsy was taken which came as acute inflammatory (suppurative) lesion on histopathological report.Now she presented with a mass of 14×10 cm over left labia majora, left perineal region, protruding into the left vaginal wall as well. Clinical examination revealed mass over vulvo-perineal region with variegated appearance and soft to firm in consistency. On per vaginum examination, the mass was extending upto the level of ischiorectal fossa. FNAC of the mass was done and the cytological report came out to be fibrolipoma. In view of benign nature of h...

Aggressive angiomyxoma of vulva and vagina: a series of three cases and review of literature

Archives of Gynecology and Obstetrics, 2011

Background Aggressive angiomyxoma is a rare locally aggressive mesenchymal tumor of unknown etiology usually affecting the vulva, perianal region, buttocks or pelvis of reproductive age women. Material A series of three cases, one each of vaginal, vulval and labial angiomyxoma is being presented. The etiology, presentation, diagnosis and management of this rare genital tumor are outlined. Conclusion Angiomyxoma of vulva and vagina refers to a rare disease; diagnosis is not at all clinical, thus, cases presenting as bartholin cyst, benign vulval lesions and vaginal wall cysts should have complete radiological work up before excision, as pre-diagnosis can change the treatment modality and prognosis of patient.

Angiomyofibroblastoma of Vulva. A Rare Tumor Entity: A Case Report

Angiomyofibroblastoma is a rare,usually small benign mesenchymal tumor that occurs mainly but not exclusively in the vulval region of premenopausal women. Patients often present with non specific symptoms. It is a well circumscribed lesion that clinically is often thought to represent a Bartholin's gland cyst. Diagnostic confusion often arise between angiomyofibroblastoma and other tumors arising in the vulval region like aggressive angiomyxoma and cellular angiofibroma because of overlapping histological features. Differentiating between angiomyofibroblastoma and cellular angiofibroma is not of clinical significance.Aggressive angiomyxoma is a more infiltrative lesion that has a high propensity for local recurrence. Immunohistochemistry is not of much help in distinguishing these entities. Sincere efforts should be made to differentiate angiomyofibroblastoma from aggressive angiomyxoma, which has a potential to metastasize or recur.

A rare case of pedunculated vulval angiomyofibroblastoma

Indian Journal of Obstetrics and Gynecology Research, 2023

A rare benign mesenchymal tumour that predominantly occurs in lower genital tract, more frequently vulvo vaginal areas of young to middle-aged women, rarely occurs in retroperitoneum. It needs to be differentiated from other benign conditions like Gartner's duct cyst, epithelial inclusion cyst, fibroepithelial polyps. It grows more slowly and is non tender, non invasive, and have least tendency for local recurrence. The histologic findings of the tumors are abundant thin-walled blood vessels with hypocellular and hypercellular areas. Almost all tumor cells have immunoreactivity for both desmin and vimentin. It also has estrogen and/or progesterone receptors, but staining for cytokeratin is negative. Here is a case of AMFB of the vulva occurring in a 62-year-old woman, involving the left labia majora. The patient described that her vulva mass grew over few years. The dimension of the tumor was measured as 18*12*4 cms. Excision biopsy done and sent for histopathology. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

Vulval Angiomyofibroblastoma - A Rare Case Report

Texila International Journal of Public Health, 2024

Angiomyofibroblastoma is a benign soft tissue tumour arising from the mesenchymal cells. It is seen in young females most commonly arising in the vulval region. This tumour mimics other benign tumours of the vulva and is pathologically differentiated from Angiofibroma and AMM (Angiomyomyxoma) which follow a different treatment protocol. This tumour is rare in occurrence and is unusual in older females. Here we report a rare case of AFMB in an older woman who presented with a very slow-growing asymptomatic vulval mass involving the left labia majora.

Angiomyofibroblastoma: a very rare tumour of vulva

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2022

Angiomyofibroblastoma is a rare benign mesenchymal tumor of vulva. Patient had history of gradually increased mass over 6 years of duration. It was painless, fibro-cystic mass of 6.8×4.6×2.5 cm hanging over right side labia majora without any menstrual or coitus difficulty. Cosmetic and risk of malignancy were the main issues. After complete examination and investigations simple excision done. Histological examination revealed mass composed of numerous capillaries and some ectatic blood vessels embedded within the hyalinised matrix. No lipomatous component was found within the tumour. Nuclear atypism and pleomorphism were absent and mitotic figures were not detected. All these were suggestive of benign mesenchymal tumor, angiomyofibroblastoma.

Aggressive angiomyxoma of vulva: a rare and interesting entity

International Surgery Journal

We report a case of a 44-year-old female with aggressive angiomyxoma arising from right labia majora. The patient presented with a gradually enlarging vulvar mass and was treatment included wide local excision of the mass with R0 resection. Pre operative and final histopathology was consistent with features of aggressive angiomyxoma. Angiomyxoma is a rare, benign, locally infiltrative mesenchymal tumor that occurs in females at reproductive age. Repeated recurrence and locally invasive characteristics of the tumor makes it important to be considered as a part of the differential diagnosis especially in cases of pelvic mass in females.

Aggressive angiomyxoma of the vulva: case report

Einstein (São Paulo), 2015

Female patient, 42-years-old, complaining of difficulty in urinating and swelling in the vulvar area for one year. Her gynecological examination showed extensive injury in the vulvar region and the biopsy done was inconclusive. The removal of the lesion was conducted. After the procedure, the patient remains free of recurrence for 15 months. This case highlights the need to consider angiomyxoma in the differential diagnosis for tumors of unknown cause in the vulvar region.

A case of aggressive angiomyxoma of the vulva

日本婦人科腫瘍学会雑誌 = The journal of the Japan Society of Gynecologic Oncology, 2007

Aggressive angiomyxoma (AA) is a rare mesenchymal neoplasm of the female pelvis and vulva, which has a tendency for local recurrence. AA is occasionally misdiagnosed as Bartholin's gland cyst or abscess, lipoma, simple labial cyst, or soft tissue tumors. We describe a case of AA on the outside of the left labium majus pudendi in a 28-year-old female. We were able to make the preoperative diagnosis of AA by magnetic resonance imaging (MRI) and ultrasound (US), and to perform complete surgical excision with a transperineal minimally invasive approach. The novelty of this case is the use of ultrasound for the diagnostic workup of the perineal tumor and determination of the incision line.