Setting Safe Acute Exposure Limits for Halon Replacement Chemicals Using Physiologically Based Pharmacokinetic Modeling (original) (raw)

Pharmacokinetics of Halothane in man: A novel approach

Й Й

1971

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Validation and Application of Pharmacokinetic Models for Interspecies Extrapolations in Toxicity Risk Assessments of Volatile Organics

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1989

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Halothane Biotransformation in Man

David J H Blake

Annals of the New York Academy of Sciences, 1971

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Toxicology Letters, 1988

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Pharmacokinetics of halogenated ethylenes in rats

Johannes G Filser

Archives of Toxicology, 1979

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Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment

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Environmental Health Perspectives, 2000

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Interspecies extrapolations of halocarbon respiratory and tissue kinetics: applications to predicting toxicity in different species

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1994

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Juan Vitali (Office of Science And Technology- The White House)

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William Boyes

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Assessing Human Variability in Kinetics for Exposures to Multiple Environmental Chemicals: A Physiologically Based Pharmacokinetic Modeling Case Study with Dichloromethane, Benzene, Toluene, Ethylbenzene, and m-Xylene

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Http Dx Doi Org 10 1080 15287394 2014 971477, 2015

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Rebecca Clewell

Regulatory Toxicology and Pharmacology, 2008

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Subcellular binding of halothane-1-14C in mouse liver and brain

David J H Blake

Journal of Pharmaceutical Sciences, 1973

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Myocardial Effects of Halothane and Isoflurane in Senescent Rats

Benoît Vivien

Anesthesiology, 2002

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Effect of halothane on myocardial infarct size in rats

Jerry Reves

Canadian Anaesthetists’ Society Journal, 1981

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Correlation of cardiotoxicity mediated by halogenated aromatic hydrocarbons to aryl hydrocarbon receptor activation

Hollie Swanson

Toxicological sciences : an official journal of the Society of Toxicology, 2001

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Comparison of the Use of a Physiologically Based Pharmacokinetic Model and a Classical Pharmacokinetic Model for Dioxin Exposure Assessments

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Stereoselective halofantrine disposition and effect:concentration-related QTc prolongation

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Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids

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Evaluation of physiologically based pharmacokinetic models for use in risk assessment

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Fatal cardiotoxicity related to halofantrine: a review based on a worldwide safety data base

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Combining physiologically based pharmacokinetic modeling with Monte Carlo simulation to derive an acute inhalation guidance value for trichloroethylene

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Hormonal and Hemodynamic Responses to Halothane and Enflurane in Spontaneously Hypertensive Rats

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Anesthesia & Analgesia, 1985

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Studies on the mechanism of haloacetonitriles toxicity: quantitative whole body autoradiographic distribution of [2-14C]chloroacetonitrile in rats

SAM JACOB

Toxicology, 1991

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Minimum alveolar concentration of halogenated volatile anaesthetics in left ventricular hypertrophy and congestive heart failure in rats

Morgan Le Guen

British Journal of Anaesthesia, 2007

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Blood/gas partition coefficients of halothane, isoflurane and sevoflurane in horse blood

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Isoflurane Does Not Prevent Hepatic Injury Produced by Halothane in Rats

Argyro Fassoulaki

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Halofantrine Safety, Tolerance and Metabolism Studies

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Effect of halothane, enflurane and isoflurane on the end-systolic pressure-length relationship

Pieter R Fourie

Canadian Journal of Anaesthesia-journal Canadien D Anesthesie, 1987

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A possible mechanism of halocarbon-induced cardiac sensitization arrhythmias

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