Anionic phospholipids are determinants of membrane protein topology (original) (raw)

Phospholipids As Determinants of Membrane Protein Topology

William Dowhan

Journal of Biological …, 2005

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Topology of polytopic membrane protein subdomains is dictated by membrane phospholipid composition

William Dowhan

The EMBO Journal, 2002

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A polytopic membrane protein displays a reversible topology dependent on membrane lipid composition

William Dowhan

The EMBO Journal, 2002

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To flip or not to flip: lipid–protein charge interactions are a determinant of final membrane protein topology

William Dowhan

Journal of Cell Biology, 2008

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Translocation of Phospholipids Is Facilitated by a Subset of Membrane-spanning Proteins of the Bacterial Cytoplasmic Membrane

Matthijs Kol

Journal of Biological Chemistry, 2003

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Forced transmembrane orientation of hydrophilic polypeptide segments in multispanning membrane proteins

Gunnar von Heijne

1998

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Lipids and topological rules governing membrane protein assembly

H. Vitrac

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013

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Phospholipid Flippases

David Daleke

Journal of Biological Chemistry, 2006

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Charged residues are major determinants of the transmembrane orientation of a signal-anchor sequence

James Beltzer

Journal of Biological Chemistry, 1991

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Structural evidence for dimerization-regulated activation of an integral membrane phospholipase

Arjan Snijder, K. Kalk

Nature, 1999

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Fine-tuning the topology of a polytopic membrane protein: role of positively and negatively charged amino acids

Gunnar von Heijne

Cell, 1990

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Forces involved in the assembly and stabilization of membrane proteins.

Gunnar von Heijne

1992

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In vitro reconstitution of lipid-dependent dual topology and postassembly topological switching of a membrane protein

H. Vitrac

Proceedings of the National Academy of Sciences, 2013

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Rotational orientation of transmembrane α-helices in bacteriorhodopsin

Donald Engelman

Journal of Molecular Biology, 1994

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A Phospholipid Acts as a Chaperone in Assembly of a Membrane Transport Protein

William Dowhan

Journal of Biological Chemistry, 1996

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Positively charged amino acid residues can act as topogenic determinants in membrane proteins

Dana Boyd

Proceedings of the National Academy of Sciences, 1989

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The Role of Charged Residues in Determining Transmembrane Protein Insertion Orientation in Yeast

Donald Tipper

Journal of Biological Chemistry, 1996

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Lipids and Topological``rules''of Membrane Protein Assembly: Testing the Generality of Net Charge Balance Rule

Heidi Vitrac

Biophysical …, 2011

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Rapid transmembrane movement of C 6-NBD-labeled phospholipids across the inner membrane of Escherichia coli

richard huijbregts

Biochimica Et Biophysica Acta-biomembranes, 1996

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Membrane proteins: shaping up

Gunnar von Heijne

2002

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Lipid-Protein Interactions Drive Membrane Protein Topogenesis in Accordance with the Positive Inside Rule

William Dowhan

Journal of Biological Chemistry, 2008

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Physiological Systems 1998-09-18 Transmembrane protein insertion orientation in yeast depends on the charge difference across transmembrane segments , their total hydrophobicity , and its distribution

Donald Tipper

2019

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Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix

Magnus Monné

Journal of Molecular Biology, 1998

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Outer Membrane Protein A of Escherichia coli Inserts and Folds into Lipid Bilayers by a Concerted Mechanism †

Jörg H . Kleinschmidt

Biochemistry, 1999

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The machinery of membrane protein assembly

Gunnar von Heijne

2004

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Polarity/charge as a determinant of translocase requirements for membrane protein insertion

Sharbani Kaushik

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2021

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Self-association of Transmembrane -Helices in Model Membranes: IMPORTANCE OF HELIX ORIENTATION AND ROLE OF HYDROPHOBIC MISMATCH

Emma Sparr

Journal of Biological Chemistry, 2005

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How Membranes Shape Protein Structure

Sajith Jayasinghe

Journal of Biological Chemistry, 2001

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Control of the Transmembrane Orientation and Interhelical Interactions within Membranes by Hydrophobic Helix Length †

Erwin London

Biochemistry, 1999

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Molecular genetic and biochemical approaches for defining lipid-dependent membrane protein folding

William Dowhan

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2012

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The Lipid Bilayer-Inserted Membrane Protein BamA of Escherichia coli Facilitates Insertion and Folding of Outer Membrane Protein A from Its Complex with Skp

Jörg H . Kleinschmidt

Biochemistry, 2013

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Structural adaptations of proteins to different biological membranes

Stephanie Tristram-nagle

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2013

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Identification of specific lipid-binding sites in membrane proteins

Marc Lensink

F1000posters, 2011

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Self-association of Transmembrane α-Helices in Model Membranes IMPORTANCE OF HELIX ORIENTATION AND ROLE OF HYDROPHOBIC MISMATCH

Emma Sparr

2005

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The headgroup conformation of phospholipids in membranes

Roland Wohlgemuth

The Journal of Membrane Biology, 1981

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