A sinister case of alopecia in a middle-aged woman (original) (raw)
Clinical and Experimental Dermatology
A 60-year-old woman presented with a 1-year history of multiple, nontender, well-defined erythematous areas of hair loss on her scalp. The patient had no medical history
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From blemishness to pathology: Reflections on a case of alopecia
Aesthetic Medicine, 2024
Alopecia areata is an organ-specific autoimmune disorder that targets anagen phase hair follicles. Taking charge of a patient with this problem is a recurring task by both dermatologists and aesthetic physicians. Less frequently, this problem may be brought to the attention of a general practitioner, internist, or endocrinologist. The immune system recognizes autologous constituents of the organism, triggering immunological responses that cause different, even multiple, pathologies in an individual. Alopecia, a complex condition represents a serious imperfection but can sometimes be a sign of autoimmunity. We present a clinical case that has come to our attention, the study of which allows us to underline the potential connection of this disease with many other autoimmune pathologies, as well as serious ones, which in the adult subject must be investigated for the purpose of early diagnosis and prompt intervention, not only aesthetic purposes.
Histopathological Diagnosis of Alopecia Clinically Relevant to Alopecia Areata
Siriraj Medical Journal
Objective: To study the histopathological diagnosis of alopecia clinically relevant to AA and to compare the histopathology between acute and chronic AA divided by time to onset at three and six months. Materials & Methods: We conducted a cross-sectional study of 113 patients with typical manifestation of AA. Two scalp biopsies were done horizontally and vertically to confirm diagnosis. Histological findings of AA in the acute group were subsequently compared with the chronic group. Results: Of the 113 eligible patients, 109 (96.5%) were pathologically diagnosed with AA. Other diagnoses included lichen planopilaris, lupus panniculitis, and unspecified scarring alopecia. The percentage of terminal telogen hairs in the acute group was significantly higher than the chronic group (mean % anagen: % telogen ratio = 21.2%:78.8% vs. 36.0%:64.0%; p = 0.016), while the chronic group had a significantly higher number of follicular streamers (mean ± SD; 2.5 ± 2.2 vs. 3.7 ± 2.6; p = 0.023). The...
Alopecia Totalis as a Presentation of Cutaneous Metastasis (Alopecia Neoplastica)
International Journal of Dermatology, 1983
UMI noti-cl "hiimp'^" oti her skull that bad coatescerl and obliterated bet hair. Tbe lesions were itc by atid tbis distoi-ntort finally niolivated ber lo see ber [ibysit ian .liter she had tried a variety of lotions wit[K)ut l.ierielit. Sbe was concerned ibdt ber family doctor carry out a regional examination only. Piiysicil examiti.ition teve.^led a thiti looking feni.ile in no distress, Tbere was rio abnorn-iaiJty of tbe cardiovascular, abdominal, central nervous sys'em, or endocrine system tioted on jietier.il exan-iination. On removing ber bairplece, it was noted that ber scalp was shinv and totally involved witb intradertnal tumor. Tbere was no bair on berscalp witb tbe exception of small narrow band in the occipital region (Figs. 1 and 2).
Medical Clinics of North America, 1998
When patients complain of hair loss (alopecia), the diagnostic possibilities are limited. Most patients with hair loss have one (or more) of a few discrete causes of alopecia, but the evaluation of alopecia remains a confusing subject for most physicians. This article aims to help primary care physicians organize their approach to the evaluation and diagnosis of hair loss.
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