Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling
Lauren Sargeant
eLife, 2018
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Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation
Ayusha Acharya
Communications Biology
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Microtissue geometry and cell-generated forces drive patterning of liver progenitor cell differentiation in 3D
erfan mohagheghian
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Viscoelastic Notch Signaling Hydrogel Induces Liver Bile Duct Organoid Growth and Morphogenesis
Tracy Liu
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Transcriptional profiling implicates TGFbeta/BMP and Notch signaling pathways in ductular differentiation of fetal murine hepatoblasts
Raquel Norel
Mechanisms of development, 2006
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Role of Mechanical Cues in Cell Differentiation and Proliferation: A 3D Numerical Model
Mohamed H. Doweidar
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Appreciating the role of cell shape changes in the mechanobiology of epithelial tissues
Yohalie Kalukula
Biophysics Reviews, 2022
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Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice
Romina Fiorotto, Barbara Torsello, Roberto Scirpo, Carlo Spirli
Journal of Hepatology, 2013
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Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure
Yannis Kalaidzidis
Journal of Cell Biology
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Quantifying cell-generated mechanical forces within living embryonic tissues
Donald Ingber
Nature Methods, 2013
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Differential proliferation rates generate patterns of mechanical tension that orient tissue growth
Yanlan Mao
The EMBO Journal, 2013
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Transcriptional profiling implicates TGFβ/BMP and Notch signaling pathways in ductular differentiation of fetal murine hepatoblasts
Raquel Norel
Mechanisms of Development, 2006
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Mechanochemical Signaling Directs Cell-Shape Change
Douglas Robinson
Biophysical Journal, 2017
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Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration
Ernesto Bockamp
Proceedings of the National Academy of Sciences, 2010
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Tissue geometry patterns epithelial-mesenchymal transition via intercellular mechanotransduction
Qike Kyle Chen
Journal of Cellular Biochemistry, 2010
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Control of cell fate decisions of embryonic stem cells by mechanical forces
Farhan Chowdhury
2011
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Analysis of Regulatory Network Involved in Mechanical Induction of Embryonic Stem Cell Differentiation
M. Jaramillo, Prashant Kumta
PLoS ONE, 2012
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Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes
Marco Tripodi
Stem Cells International, 2016
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Influence of cell mechanics in embryonic bile duct lumen formation: insight from quantitative modeling
Dirk Drasdo
HAL (Le Centre pour la Communication Scientifique Directe), 2021
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Mechanisms of Regulating Cell Topology in Proliferating Epithelia: Impact of Division Plane, Mechanical Forces, and Cell Memory
Yingzi Li
PLoS ONE, 2012
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Mechanics Regulate Human Embryonic Stem Cell Self-Organization to Specify Mesoderm
Valerie M. Weaver
SSRN Electronic Journal
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Hepatic Tumor Cell Morphology Plasticity under Physical Constraints in 3D Cultures Driven by YAP–mTOR Axis
Sarka Kubinova
Pharmaceuticals, 2020
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Cell Lineages in Hepatic Development and Molecular Mechanisms of Cell-Cell Interactions Underlying Hepatoblast Differentiation into Mature Hepatocytes and Biliary Epithelial Cells
Global Science Books
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Spatially patterned matrix elasticity directs stem cell fate
Kristi Anseth
Proceedings of the National Academy of Sciences of the United States of America, 2016
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Modeling Liver Organogenesis by Recreating Three-Dimensional Collective Cell Migration: A Role for TGFβ Pathway
osama yousef
Frontiers in Bioengineering and Biotechnology, 2021
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Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche
Eliane Wauthier
Biomaterials, 2011
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Quantitative modeling identifies critical cell mechanics driving bile duct lumen formation
Dirk Drasdo
PLOS Computational Biology, 2022
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Emergence of homeostatic epithelial packing and stress dissipation through divisions oriented along the long cell axis
Maxine Lam
Proceedings of the National Academy of Sciences of the United States of America, 2015
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Ductular reaction-on-a-chip: Microfluidic co-cultures to study stem cell fate selection during liver injury
Gulnaz Stybayeva
Scientific Reports, 2016
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Biomechanics of cultured hepatic cells during different steatogenic hits
Martina Ardito
Journal of the Mechanical Behavior of Biomedical Materials, 2019
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A predictive computational model shows that biomechanical cell cycle progression control can explain liver regeneration after partial hepatectomy
Dirk Drasdo
2021
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Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy
Dirk Drasdo
iScience
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Regulation of tensile stress in response to external forces coordinates epithelial cell shape transitions with organ growth and elongation
Vanessa Weichselberger
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Biomechanical regulation of cell orientation and fate
jose lopez
Oncogene, 2008
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Mechanical forces mediate localized topological change in epithelia
Yingzi Li
2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2011
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