Thematic Review Series: Living History of Lipids The arachidonic acid monooxygenase: from biochemical curiosity to physiological/pathophysiological significance (original) (raw)

Cytochrome P450 and the Metabolism and Bioactivation of Arachidonic Acid and Eicosanoids

Jorge Capdevila

Cytochrome P450

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Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase

Jorge Capdevila

Journal of Lipid Research, 2000

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Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of ω-3 Fatty Acids*

Gerd Wallukat

Journal of Biological Chemistry, 2010

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Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450

Laurent Corcos

Archives of Biochemistry and Biophysics, 2008

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Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of -3 Fatty Acids

Gerd Wallukat

Journal of Biological Chemistry, 2010

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Arachidonic Acid-Metabolizing Cytochrome P450 Enzymes Are Targets of OMEGA3 Fatty Acids

Clemens von Schacky

Journal of Biological Chemistry, 2010

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Nutritionally triggered alterations in the regiospecificity of arachidonic acid oxygenation by rat liver microsomal cytochrome P450

J. Capdevila

Archives of Biochemistry and Biophysics, 1989

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Cytochrome P450/NADPH-dependent biosynthesis of 5,6-trans-epoxyeicosatrienoic acid from 5,6-trans-arachidonic acid

Robert Joshua

Biochemical Journal, 2005

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Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism

Ian Mason

Archives of Biochemistry and Biophysics, 1988

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Determination of the Dominant Arachidonic Acid Cytochrome P450 Monooxygenases in Rat Heart, Lung, Kidney, and Liver: Protein Expression and Metabolite Kinetics

Beshay Zordoky

The AAPS Journal, 2013

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Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids

Jorge Capdevila

Proceedings of the National Academy of Sciences, 1982

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Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid

Jorge Capdevila

Proceedings of the National Academy of Sciences, 1981

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Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1

J. R Falck

Journal of Biological Chemistry, 1993

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The Highly Stereoselective Oxidation of Polyunsaturated Fatty Acids by Cytochrome P450BM-3

J. R Falck

Journal of Biological Chemistry, 1996

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Analysis of Cytochrome P450 Metabolites of Arachidonic and Linoleic Acids by Liquid Chromatography–Mass Spectrometry with Ion Trap MS2

Johan Bylund

Analytical Biochemistry, 1998

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Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17( R),18( S)-epoxyeicosatetraenoic acid

Spencer S Ericksen

Biochemical Pharmacology, 2004

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Cytochrome P450 Epoxygenase Metabolism of Arachidonic Acid Inhibits Apoptosis

Jorge Capdevila

Molecular and Cellular Biology, 2001

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Nutritionally triggered alterations in the regiospecificity of arachidonic acid oxygenation by rat liver microsomal cytochrome P450* 1

Lionel Gil

Archives of biochemistry and …, 1989

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Liquid Chromatographic–Electrospray Ionization–Mass Spectrometric Analysis of Cytochrome P450 Metabolites of Arachidonic Acid

Gary Beecher

Analytical Biochemistry, 2001

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Arachidonic Acid Metabolism in the Marine FishStenotomus chrysops(Scup) and the Effects of Cytochrome P450 1A Inducers

Jennifer Schlezinger, John Stegeman

Archives of Biochemistry and Biophysics, 1998

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Cytochrome P450scc-substrate interactions. Studies of binding and catalytic activity using hydroxycholesterols. J Biol Chem 257: 1876-1884

Robert Tuckey

Journal of Biological Chemistry

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Convergent Oxygenation of Arachidonic Acid by 5-Lipoxygenase and Cyclooxygenase-2

Huiyong Yin

Journal of the American Chemical Society, 2006

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Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450

Laurent Corcos

The Journal of Lipid Research, 2010

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CYP2U1, a Novel Human Thymus- and Brain-specific Cytochrome P450, Catalyzes - and ( -1)-Hydroxylation of Fatty Acids

Samuel Chuang

Journal of Biological Chemistry, 2003

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CYP2U1, a Novel Human Thymus- and Brain-specific Cytochrome P450, Catalyzes ω- and (ω-1)-Hydroxylation of Fatty Acids

Christian Helvig

Journal of Biological Chemistry, 2003

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The Role of Vitamin E and Selenium on Arachidonic Acid Oxidation by way of the 5-Lipoxygenase Pathway

P. Reddanna

Annals of the New York Academy of Sciences, 1989

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Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450

Jorge Capdevila

Archives of Biochemistry and Biophysics, 1985

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Cytochrome P450-Dependent Oxidation of Fatty Acids

Christian Helvig

Drug Metabolism and Drug Interactions, 1995

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Cytochrome P450 IIIA1 (P450p) requires cytochrome b5 and phospholipid with unsaturated fatty acids

Derek Eberhart

Archives of Biochemistry and Biophysics, 1991

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Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 monooxygenase

J. Capdevila

Circulation Research, 1987

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