Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism (original) (raw)

Cytochrome P450 and the Metabolism and Bioactivation of Arachidonic Acid and Eicosanoids

Jorge Capdevila

Cytochrome P450

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Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase

Jorge Capdevila

Journal of Lipid Research, 2000

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Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids

Jorge Capdevila

Proceedings of the National Academy of Sciences, 1982

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Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid

Jorge Capdevila

Proceedings of the National Academy of Sciences, 1981

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Nutritionally triggered alterations in the regiospecificity of arachidonic acid oxygenation by rat liver microsomal cytochrome P450

J. Capdevila

Archives of Biochemistry and Biophysics, 1989

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Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450

Jorge Capdevila

Archives of Biochemistry and Biophysics, 1985

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Arachidonate epoxygenase: inhibitors and metabolite analogues

J. Capdevila

Tetrahedron Letters, 1985

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Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450

Laurent Corcos

Archives of Biochemistry and Biophysics, 2008

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Liquid Chromatographic–Electrospray Ionization–Mass Spectrometric Analysis of Cytochrome P450 Metabolites of Arachidonic Acid

Gary Beecher

Analytical Biochemistry, 2001

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Determination of the Dominant Arachidonic Acid Cytochrome P450 Monooxygenases in Rat Heart, Lung, Kidney, and Liver: Protein Expression and Metabolite Kinetics

Beshay Zordoky

The AAPS Journal, 2013

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2,3,7,8-Tetrachlorodibenzo-p-dioxin Induction of Cytochrome P450-Dependent Arachidonic Acid Metabolism in Mouse Liver Microsomes: Evidence for Species-Specific Differences in Responses

Nancy Kerkvliet

Toxicology and Applied Pharmacology, 1998

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Effects of dronedarone, amiodarone and their active metabolites on sequential metabolism of arachidonic acid to epoxyeicosatrienoic and dihydroxyeicosatrienoic acids

Nhan Tram

Biochemical Pharmacology, 2017

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Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations

Joseph Chang

Inflammation, 1984

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Cytochrome P450 Epoxygenase Metabolism of Arachidonic Acid Inhibits Apoptosis

Jorge Capdevila

Molecular and Cellular Biology, 2001

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Convergent Oxygenation of Arachidonic Acid by 5-Lipoxygenase and Cyclooxygenase-2

Huiyong Yin

Journal of the American Chemical Society, 2006

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The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance

John Szarek

Journal of Clinical Investigation, 1995

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Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of ω-3 Fatty Acids*

Gerd Wallukat

Journal of Biological Chemistry, 2010

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Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1

J. R Falck

Journal of Biological Chemistry, 1993

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Renal cytochrome P-450-dependent metabolism of arachidonic acid in cirrhotic rats

D. Sacerdoti

Journal of Hepatology, 1991

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Cytotoxicity and Apoptosis Produced by Arachidonic Acid in HepG2 Cells Overexpressing Human Cytochrome P‐4502E1

Monica Galleano

Alcoholism: Clinical and Experimental Research, 1998

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Arachidonic Acid-Metabolizing Cytochrome P450 Enzymes Are Targets of OMEGA3 Fatty Acids

Clemens von Schacky

Journal of Biological Chemistry, 2010

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Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of -3 Fatty Acids

Gerd Wallukat

Journal of Biological Chemistry, 2010

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Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 monooxygenase

J. Capdevila

Circulation Research, 1987

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Nutritionally triggered alterations in the regiospecificity of arachidonic acid oxygenation by rat liver microsomal cytochrome P450* 1

Lionel Gil

Archives of biochemistry and …, 1989

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SK&F 86002: A structurally novel anti-inflammatory agent that inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid

George Poste

Biochemical Pharmacology, 1987

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Arachidonic Acid Inhibits Epithelial Na Channel Via Cytochrome P450 (CYP) Epoxygenase-dependent Metabolic Pathways

Rowena Kemp

Journal of General Physiology, 2004

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Affinities of various mammalian arachidonate lipoxygenases and cyclooxygenases for molecular oxygen as substrate

Ivo Juránek

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1999

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Cyclooxygenase-2-Mediated Metabolism of Arachidonic Acid to 15-Oxo-eicosatetraenoic Acid by Rat Intestinal Epithelial Cells

/간호학과 이선희

Chemical Research in Toxicology, 2007

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Ethoxy-, pentoxy-and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

Richard Mayer

Biochemical …, 1985

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Thematic Review Series: Living History of Lipids The arachidonic acid monooxygenase: from biochemical curiosity to physiological/pathophysiological significance

Jorge Capdevila

Journal of Lipid Research, 2018

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The Role of Vitamin E and Selenium on Arachidonic Acid Oxidation by way of the 5-Lipoxygenase Pathway

P. Reddanna

Annals of the New York Academy of Sciences, 1989

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Cytochrome P450/NADPH-dependent biosynthesis of 5,6-trans-epoxyeicosatrienoic acid from 5,6-trans-arachidonic acid

Robert Joshua

Biochemical Journal, 2005

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Arachidonic acid epoxygenase

Jorge Capdevila

FEBS Letters, 1990

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