Structural Basis for the Decarboxylation of Orotidine 5'-Monophosphate (OMP) by Plasmodium Falciparum OMP Decarboxylase (original) (raw)
The in silico screening and X-ray structure analysis of the inhibitor complex of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase
Tsuyoshi Inoue
Journal of Biochemistry, 2012
View PDFchevron_right
Structural determinants for the inhibitory ligands of orotidine-5′-monophosphate decarboxylase
Angelica Bello
Bioorganic & Medicinal Chemistry, 2010
View PDFchevron_right
Structural Determinants for Inhibitory Ligands of Orotidine-5'-Monophosphate Decarboxylase
Mara Bello
Bioorganic & Medicinal …, 2010
View PDFchevron_right
The Crystal Structure of Plasmodium falciparum Glutamate Dehydrogenase, a Putative Target for Novel Antimalarial Drugs
Gerhard Klebe
Journal of Molecular Biology, 2005
View PDFchevron_right
The crystal structure and mechanism of orotidine 5'-monophosphate decarboxylase
Cynthia Kinsland
Proceedings of the National Academy of Sciences, 2000
View PDFchevron_right
Structure–Activity Relationships of C6Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase
Angelica Bello, Ian Crandall
Journal of Medicinal Chemistry, 2008
View PDFchevron_right
Comparative properties of a three-dimensional model of Plasmodium falciparum ornithine decarboxylase
Lyn-marie Birkholtz
Proteins, 2003
View PDFchevron_right
Crystal Structure of Plasmodium falciparum ADP-Ribosylation Factor 1
Sakunrat Ubonprasert
2010
View PDFchevron_right
Homology Modelling and Binding Site Identification of 1DEOXY D-Xylulose 5 Phosphate Reductoisomerase of Plasmodium Falciparum: New Drug Target for Plsmodium Falciparum
Shailendra Gupta
View PDFchevron_right
Plasmodium vivax 1-deoxy-D-xylulose-5-phosphate synthase: HomologyModeling, Domain Swapping,and Virtual Screening
Divya Ramamoorthy
Journal of Data Mining in Genomics & Proteomics, 2014
View PDFchevron_right
Structural Plasticity of Malaria Dihydroorotate Dehydrogenase Allows Selective Binding of Diverse Chemical Scaffolds
Werner Kaminsky
Journal of Biological Chemistry, 2009
View PDFchevron_right
X-ray Crystal Structure and Specificity of the Plasmodium falciparum Malaria Aminopeptidase PfM18AAP
Sheena McGowan
Journal of Molecular Biology, 2012
View PDFchevron_right
A Potent, Covalent Inhibitor of Orotidine 5‘-Monophosphate Decarboxylase with Antimalarial Activity
Angelica Mara Bello
Journal of Medicinal Chemistry, 2007
View PDFchevron_right
Transition State Analogues of Plasmodium falciparum and Human Orotate Phosphoribosyltransferases
Gary Evans
Journal of Biological Chemistry, 2013
View PDFchevron_right
Novel properties of malarial S-adenosylmethionine decarboxylase as revealed by structural modelling
Abraham Louw
Journal of Molecular Graphics & Modelling, 2006
View PDFchevron_right
Orotate phosphoribosyltransferase and orotidine 5′-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum
Hiroshi Ashihara
Biochemical and Biophysical Research Communications, 2004
View PDFchevron_right
Supplemental Data Structures of the Human Orotidine5'Monophosphate Decarboxylase Support a Covalent Mechanism and Provide a Framework for Drug Design
Ulf Diederichsen
View PDFchevron_right
Structure of the (E)-4-hydroxy-3-methyl-but-2-enyl-diphosphate reductase from Plasmodium falciparum
Evert Duin
FEBS Letters, 2013
View PDFchevron_right
Structural Characterization of the Molecular Events during a Slow Substrate–Product Transition in Orotidine 5′-Monophosphate Decarboxylase
Emil Pai
Journal of Molecular Biology, 2009
View PDFchevron_right
Comparative Analysis of Novel Targets for Antimalarial Drugs: Structural and Mechanistic Insights about Plasmodium falciparum Enzymes
Kumar Gaurav Shankar
2012
View PDFchevron_right
Structural analysis of chorismate synthase from Plasmodium falciparum: A novel target for antimalaria drug discovery
Satya Tapas
View PDFchevron_right
Substrate Binding Induces Domain Movements in Orotidine 5′-Monophosphate Decarboxylase
Jens-christian Poulsen
Journal of Molecular Biology, 2002
View PDFchevron_right
An improved crystal form of Plasmodium falciparum peptide deformylase
Abhinav Kumar
Protein Science, 2004
View PDFchevron_right
Antimalarial drug discovery: in silico structural biology and rational drug design
Lyn-marie Birkholtz
2009
View PDFchevron_right
Crystal Structure of Fully Ligated Adenylosuccinate Synthetase from Plasmodium falciparum
MRN Murthy
Journal of Molecular Biology, 2004
View PDFchevron_right
Aspartate carbamoyltransferase of Plasmodium falciparum as a potential drug target for designing anti-malarial chemotherapeutic agents.
Amit K U M A R Banerjee
Medicinal Chemistry Research, 2011
View PDFchevron_right