Whole Foods Research Papers - Academia.edu (original) (raw)

This study examined whether blueberries or vitamin C consumed for 7 days in a randomized, double-blind, crossover design would attenuate oxidative stress and cytokine changes versus placebo. Nine subjects ran at 70% VO2max in a... more

This study examined whether blueberries or vitamin C consumed for 7 days in a randomized,
double-blind, crossover design would attenuate oxidative stress and cytokine changes versus placebo.
Nine subjects ran at 70% VO2max in a hyperthermic environment (35°C, 70% relative humidity [RH])
until a core temperature of 39.5°C was reached, and for an equivalent time and intensity in the two
remaining treatments. Blood samples were drawn before exercise and immediately, 15 minutes, and
30 minutes after exercise. Plasma samples were analyzed for F2-isoprostanes, lipid hydroperoxides,
vitamin C, ferric reducing antioxidant potential, urate, interleukin-1ra, interleukin-6, interleukin-8, and
interleukin-10. The pattern of change between treatments was significant for lipid hydroperoxides but
not for any other marker. Significant correlations were found between F2-isoprostanes, lipid hydroperoxides,
ferric reducing antioxidant potential, and urate. This study indicates that blueberry supplementation
may be beneficial for athletes exercising in hot environments.