Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. (original) (raw)
- Journal List
- J Clin Pathol
- v.33(12); 1980 Dec
- PMC1146371
J Clin Pathol. 1980 Dec; 33(12): 1179–1183.
Abstract
Legionella pneumophila, the causative organism of Legionnaires' disease, is pathogenic for free living, ubiquitous, freshwater, and soil amoebae of the genera Acanthamoeba and Naegleria. Some species support the growth of strains from serogroups 1 to 6, others only strains from certain serogroups. Initial studies with seeded material indicate that amoebal enrichment could be utilised for the isolation of legionellae from clinical specimens and natural habitats. It is suggested that a vacuole, or amoeba, full of legionellae, rather than free legionellae, could be the infective particle for man.
Full text
Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (971K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.
Images in this article
Click on the image to see a larger version.
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Morris GK, Patton CM, Feeley JC, Johnson SE, Gorman G, Martin WT, Skaliy P, Mallison GF, Politi BD, Mackel DC. Isolation of the Legionnaires' disease bacterium from environmental samples. Ann Intern Med. 1979 Apr;90(4):664–666. [PubMed] [Google Scholar]
- Dondero TJ, Jr, Rendtorff RC, Mallison GF, Weeks RM, Levy JS, Wong EW, Schaffner W. An outbreak of Legionnaires' disease associated with a contaminated air-conditioning cooling tower. N Engl J Med. 1980 Feb 14;302(7):365–370. [PubMed] [Google Scholar]
- Cordes LG, Fraser DW, Skaliy P, Perlino CA, Elsea WR, Mallison GF, Hayes PS. Legionnaires' disease outbreak at an Atlanta, Georgia, Country Club: evidence for spread from an evaporative condenser. Am J Epidemiol. 1980 Apr;111(4):425–431. [PubMed] [Google Scholar]
- Fliermans CB, Cherry WB, Orrison LH, Thacker L. Isolation of Legionella pneumophila from nonepidemic-related aquatic habitats. Appl Environ Microbiol. 1979 Jun;37(6):1239–1242. [PMC free article] [PubMed] [Google Scholar]
- Skaliy P, McEachern HV. Survival of the Legionnaires' disease bacterium in water. Ann Intern Med. 1979 Apr;90(4):662–663. [PubMed] [Google Scholar]
- Wang WL, Blaser MJ, Cravens J, Johnson MA. Growth, survival, and resistance of the Legionnaires' disease bacterium. Ann Intern Med. 1979 Apr;90(4):614–618. [PubMed] [Google Scholar]
- Pine L, George JR, Reeves MW, Harrell WK. Development of a chemically defined liquid medium for growth of Legionella pneumophila. J Clin Microbiol. 1979 May;9(5):615–626. [PMC free article] [PubMed] [Google Scholar]
- George JR, Pine L, Reeves MW, Harrell WK. Amino acid requirements of Legionella pneumophila. J Clin Microbiol. 1980 Mar;11(3):286–291. [PMC free article] [PubMed] [Google Scholar]
- Brenner DJ, Steigerwalt AG, McDade JE. Classification of the Legionnaires' disease bacterium: Legionella pneumophila, genus novum, species nova, of the family Legionellaceae, familia nova. Ann Intern Med. 1979 Apr;90(4):656–658. [PubMed] [Google Scholar]
- Feeley JC, Gorman GW, Weaver RE, Mackel DC, Smith HW. Primary isolation media for Legionnaires disease bacterium. J Clin Microbiol. 1978 Sep;8(3):320–325. [PMC free article] [PubMed] [Google Scholar]
- Rutter DA, Maber HB. Culture of Legionella pneumophila. Lancet. 1979 Mar 31;1(8118):723–724. [PubMed] [Google Scholar]
- Tison DL, Pope DH, Cherry WB, Fliermans CB. Growth of Legionella pneumophila in association with blue-green algae (cyanobacteria). Appl Environ Microbiol. 1980 Feb;39(2):456–459. [PMC free article] [PubMed] [Google Scholar]
- Chandler FW, Cole RM, Hicklin MD, Blackmon JA, Callaway CS. Ultrastructure of the Legionnaires' disease bacterium. A study using transmission electron microscopy. Ann Intern Med. 1979 Apr;90(4):642–647. [PubMed] [Google Scholar]
- Glavin FL, Winn WC, Jr, Craighead JE. Ultrastructure of lung in Legionnaires' disease. Observations of three biopsies done during the Vermont epidemic. Ann Intern Med. 1979 Apr;90(4):555–559. [PubMed] [Google Scholar]
- Rodgers FG. Ultrastructure of Legionella pneumophila. J Clin Pathol. 1979 Dec;32(12):1195–1202. [PMC free article] [PubMed] [Google Scholar]
- Kishimoto RA, Kastello MD, White JD, Shirey FG, McGann VG, Larson EW, Hedlund KW. In vitro interaction between normal cynolmolgus monkey alveolar macrophages and Legionnaires disease bacteria. Infect Immun. 1979 Aug;25(2):761–763. [PMC free article] [PubMed] [Google Scholar]
- Johnson W, Pesanti E, Elliott J. Serospecificity and opsonic activity of antisera to Legionella pneumophila. Infect Immun. 1979 Nov;26(2):698–704. [PMC free article] [PubMed] [Google Scholar]
- Chandler FW, McDade JE, Hicklin MD, Blackmon JA, Thomason BM, Ewing EP., Jr Pathologic findings in guinea pigs inoculated intraperitoneally with the Legionnaires' disease bacterium. Ann Intern Med. 1979 Apr;90(4):671–675. [PubMed] [Google Scholar]
- Greaves PG, Sharp G, Macrae AD. Isolation of Legionella pneumophila. Lancet. 1979 Mar 10;1(8115):551–552. [PubMed] [Google Scholar]
- Miller RP. Cooling towers and evaporative condensers. Ann Intern Med. 1979 Apr;90(4):667–670. [PubMed] [Google Scholar]
- GIMENEZ DF. STAINING RICKETTSIAE IN YOLK-SAC CULTURES. Stain Technol. 1964 May;39:135–140. [PubMed] [Google Scholar]
- Taylor AG, Harrison TG. Legionnaires' disease caused by Legionella pneumophila serogroup 3. Lancet. 1979 Jul 7;2(8132):47–47. [PubMed] [Google Scholar]
- Fallon RJ, Abraham WH. Legionnaires' disease caused by Legionella pneumophila serogroup 3. Lancet. 1979 Aug 11;2(8137):304–304. [PubMed] [Google Scholar]
- Fisher-Hoch S, Hudson MJ, Thompson MH. Identification of a clinical isolate as Legionella pneumophila by gas chromatography and mass spectrometry of cellular fatty acids. Lancet. 1979 Aug 18;2(8138):323–325. [PubMed] [Google Scholar]
- Hernandez FJ, Kirby BD, Stanley TM, Edelstein PH. Legionnaires' disease. Postmortem pathologic findings of 20 cases. Am J Clin Pathol. 1980 Apr;73(4):488–495. [PubMed] [Google Scholar]
- Broome CV, Fraser DW. Epidemiologic aspects of legionellosis. Epidemiol Rev. 1979;1:1–16. [PubMed] [Google Scholar]
- Fraser DW, Tsai TR, Orenstein W, Parkin WE, Beecham HJ, Sharrar RG, Harris J, Mallison GF, Martin SM, McDade JE, et al. Legionnaires' disease: description of an epidemic of pneumonia. N Engl J Med. 1977 Dec 1;297(22):1189–1197. [PubMed] [Google Scholar]
- Cordes LG, Wilkinson HW, Gorman GW, Fikes BJ, Fraser DW. Atypical Legionella-like organisms: fastidious water-associated bacteria pathogenic for man. Lancet. 1979 Nov 3;2(8149):927–930. [PubMed] [Google Scholar]
- Lewallen KR, McKinney RM, Brenner DJ, Moss CW, Dail DH, Thomason BM, Bright RA. A newly identified bacterium phenotypically resembling, but genetically distinct from, Legionella pneumophila: an isolate in a case of pneumonia. Ann Intern Med. 1979 Dec;91(6):831–834. [PubMed] [Google Scholar]
Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group