Raspberry differentially improves age-related declines in psychomotor function dependent on baseline motor ability - PubMed (original) (raw)
. 2017 Dec 13;8(12):4752-4759.
doi: 10.1039/c7fo00894e.
Affiliations
- PMID: 29168860
- DOI: 10.1039/c7fo00894e
Raspberry differentially improves age-related declines in psychomotor function dependent on baseline motor ability
Barbara Shukitt-Hale et al. Food Funct. 2017.
Abstract
Among older adults, falls are a leading cause of distress, pain, injury, loss of confidence, and ultimately, loss of independence and death. Previous studies in our laboratory have demonstrated that berry supplementation improves the age-related declines in balance, muscle strength, and coordination that often lead to falls, even when initiated later in life. The purpose of this study was to explore the interaction between baseline motor performance and the daily intake of raspberry required to improve/preserve motor function. Aged male F344 (17 mo) rats were tested for baseline (pre-test) balance, muscle strength, and coordination, and divided into good, average, and poor performers based on their motor composite score. Rats in each category were fed with either a control, 1%, or 2% raspberry-supplemented diet for 8 weeks and then retested (post-test). Poor performers fed with 1% or 2% raspberry had higher post-test composite scores (p < 0.05), while 2% raspberry lowered post-test composite scores in the good performers (p < 0.05), compared to control-fed rats. 1% and 2% raspberry appeared to preserve the performance of good performers and improve the performance of poor performers on plank walking (p < 0.05), while 2% raspberry improved post-test grip strength of the poor performers (p < 0.05). Additionally, rats with lower post-diet composite scores had higher levels of serum IL-1β levels (r = -0.347, p < 0.05). These findings identified poor performers as being the most likely to benefit from daily consumption of ½-2 cups of raspberry to improve/preserve motor function. Therefore, increased raspberry consumption may reduce fall risk, extend independence, and improve quality of life in the aging population.
Similar articles
- Effects of blackberries on motor and cognitive function in aged rats.
Shukitt-Hale B, Cheng V, Joseph JA. Shukitt-Hale B, et al. Nutr Neurosci. 2009 Jun;12(3):135-40. doi: 10.1179/147683009X423292. Nutr Neurosci. 2009. PMID: 19356316 - Chemical composition of defatted strawberry and raspberry seeds and the effect of these dietary ingredients on polyphenol metabolites, intestinal function, and selected serum parameters in rats.
Kosmala M, Zduńczyk Z, Juśkiewicz J, Jurgoński A, Karlińska E, Macierzyński J, Jańczak R, Rój E. Kosmala M, et al. J Agric Food Chem. 2015 Mar 25;63(11):2989-96. doi: 10.1021/acs.jafc.5b00648. Epub 2015 Mar 16. J Agric Food Chem. 2015. PMID: 25746061 - Dose-dependent effects of walnuts on motor and cognitive function in aged rats.
Willis LM, Shukitt-Hale B, Cheng V, Joseph JA. Willis LM, et al. Br J Nutr. 2009 Apr;101(8):1140-4. doi: 10.1017/S0007114508059369. Br J Nutr. 2009. PMID: 18778529 - [Aging and physical activity data on which to base recommendations for exercise in older adults].
Paterson DH, Jones GR, Rice CL. Paterson DH, et al. Appl Physiol Nutr Metab. 2007;32 Suppl 2F:S75-S171. doi: 10.1139/H07-165. Appl Physiol Nutr Metab. 2007. PMID: 19377547 Review. French. - [Physical activity diminishes aging-related decline of physical and cognitive performance].
Apor P, Babai L. Apor P, et al. Orv Hetil. 2014 May 25;155(21):817-21. doi: 10.1556/OH.2014.29838. Orv Hetil. 2014. PMID: 24836316 Review. Hungarian.
Cited by
- Berry Fruits and Their Improving Potential on Skeletal Muscle Health and Performance: A Systematic Review of the Evidence in Animal and in Human Studies.
Moroni A, Zupo R, Castellana F, Amirante F, Zese M, Rondanelli M, Riso P, Perna S. Moroni A, et al. Foods. 2024 Jul 13;13(14):2210. doi: 10.3390/foods13142210. Foods. 2024. PMID: 39063294 Free PMC article. Review. - A mixture of Nordic berries improves cognitive function, metabolic function and alters the gut microbiota in C57Bl/6J male mice.
Huang F, Marungruang N, Martinsson I, Camprubí Ferrer L, Nguyen TD, Gondo TF, Karlsson EN, Deierborg T, Öste R, Heyman-Lindén L. Huang F, et al. Front Nutr. 2023 Oct 3;10:1257472. doi: 10.3389/fnut.2023.1257472. eCollection 2023. Front Nutr. 2023. PMID: 37854349 Free PMC article. - The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro.
Rutledge GA , Fisher DR , Miller MG , Kelly ME , Bielinski DF , Shukitt-Hale B . Rutledge GA , et al. Food Funct. 2019 Dec 11;10(12):7707-7713. doi: 10.1039/c9fo01913h. Food Funct. 2019. PMID: 31746877 Free PMC article. Clinical Trial. - Blueberries Improve Neuroinflammation and Cognition differentially Depending on Individual Cognitive baseline Status.
Shukitt-Hale B, Thangthaeng N, Miller MG, Poulose SM, Carey AN, Fisher DR. Shukitt-Hale B, et al. J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):977-983. doi: 10.1093/gerona/glz048. J Gerontol A Biol Sci Med Sci. 2019. PMID: 30772901 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical