Effects of supplementation with high-selenium wheat bread on selenium, glutathione peroxidase and related enzymes in blood components of New Zealand residents - PubMed (original) (raw)
Effects of supplementation with high-selenium wheat bread on selenium, glutathione peroxidase and related enzymes in blood components of New Zealand residents
C D Thomson et al. Am J Clin Nutr. 1985 May.
Abstract
The effects of supplementation with high-Se wheat bread on selenium (Se) concentrations, glutathione peroxidase (EC 1.11.1.9, GSHPx) activities and related enzymes in the prevention of lipid peroxidation were studied. Four New Zealand women were supplemented with 200 micrograms Se daily for 8-13 weeks followed by a post-dosing period of 9-12 weeks. GSHPx activities increased in whole blood, erythrocytes, plasma and platelets of all subjects but increases were considerably less than those of Se concentrations in whole blood, plasma and erythrocytes. During the post-dosing period Se concentrations and GSHPx activities fell to levels which were in most cases somewhat higher than baseline values. Glutathione-S-transferase activities in erythrocytes, plasma and platelets did not change during the study, nor did superoxide dismutase in erythrocytes and platelets, erythrocyte catalase or plasma alpha-tocopherol. Thus Se supplementation of healthy New Zealand subjects increased GSHPx activities but did not produce any adaptive changes in other components of the lipid peroxidation defense mechanisms.
Similar articles
- Long-term supplementation with selenate and selenomethionine: selenium and glutathione peroxidase (EC 1.11.1.9) in blood components of New Zealand women.
Thomson CD, Robinson MF, Butler JA, Whanger PD. Thomson CD, et al. Br J Nutr. 1993 Mar;69(2):577-88. doi: 10.1079/bjn19930057. Br J Nutr. 1993. PMID: 8490010 Clinical Trial. - Human selenium supplementation as assessed by changes in blood selenium concentration and glutathione peroxidase activity.
Nève J. Nève J. J Trace Elem Med Biol. 1995 Jul;9(2):65-73. doi: 10.1016/S0946-672X(11)80013-1. J Trace Elem Med Biol. 1995. PMID: 8825978 Review. - Selenium in human health and disease with emphasis on those aspects peculiar to New Zealand.
Thomson CD, Robinson MF. Thomson CD, et al. Am J Clin Nutr. 1980 Feb;33(2):303-23. doi: 10.1093/ajcn/33.2.303. Am J Clin Nutr. 1980. PMID: 6766657 Review.
Cited by
- The potential role of phytochemicals in wholegrain cereals for the prevention of type-2 diabetes.
Belobrajdic DP, Bird AR. Belobrajdic DP, et al. Nutr J. 2013 May 16;12:62. doi: 10.1186/1475-2891-12-62. Nutr J. 2013. PMID: 23679924 Free PMC article. Review. - Serum antioxidants and inflammation predict red cell distribution width in older women: the Women's Health and Aging Study I.
Semba RD, Patel KV, Ferrucci L, Sun K, Roy CN, Guralnik JM, Fried LP. Semba RD, et al. Clin Nutr. 2010 Oct;29(5):600-4. doi: 10.1016/j.clnu.2010.03.001. Epub 2010 Mar 23. Clin Nutr. 2010. PMID: 20334961 Free PMC article. - Effect of dietary selenium and vitamin E on the biomechanical properties of rabbit bones.
Turan B, Balcik C, Akkas N. Turan B, et al. Clin Rheumatol. 1997 Sep;16(5):441-9. doi: 10.1007/BF02238935. Clin Rheumatol. 1997. PMID: 9348137 - Effect of radiotherapy and chemoradiotherapy on circulating antioxidant system of human uterine cervical carcinoma.
Bhuvarahamurthy V, Balasubramanian N, Govindasamy S. Bhuvarahamurthy V, et al. Mol Cell Biochem. 1996 May 10;158(1):17-23. doi: 10.1007/BF00225878. Mol Cell Biochem. 1996. PMID: 8791280 Clinical Trial. - Physiological and nutritional importance of selenium.
Nève J. Nève J. Experientia. 1991 Feb 15;47(2):187-93. doi: 10.1007/BF01945424. Experientia. 1991. PMID: 2001724 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials