Original Research (original) (raw)
JCP
Original Research
Cardiovascular Risk Factors and Second Generation Antipsychotics
January 8, 2025
Despite well-documented cardiovascular disease (CVD) morbidity and mortality, CVD risks among people with severe mental illness who use antipsychotics are common and frequently untreated.
Virginie-Anne Chouinard, Mary Price, Sophie Forte, et al
JCP
Original Research
IV Hydroxyzine vs Haloperidol for Delirium
January 6, 2025
Hydroxyzine showed a significantly higher rate of delirium improvement than haloperidol, with no significant difference in the time to improvement.
Kaoruhiko Kubo, Moe Takehara, Mayuko Hirata, et al
JCP
Original Research
Olanzapine/Samidorphan Effects on Weight Gain
January 2, 2025
Treatment with a combination of olanzapine and samidorphan was associated with less weight gain and reduced risk of reaching ≥7% or ≥10% gain in body weight versus olanzapine over...
Christoph U. Correll, Michael J. Doane, David McDonnell, et al
JCP
Original Research
Substance and Opioid Use Disorders Among IBD Hospitalizations
January 2, 2025
A higher prevalence of SUD and opioid use disorder was found among hospitalizations for inflammatory bowel disease, and these elevated prevalences were linked to distinct demographic, socioeconomic, and geographic...
Jin S. Kim, Patrick W. Chang, Jason Hung, et al
JCP
Original Research
Treatments and Treatment Predictors in Patients With SUDs and ADHD
December 23, 2024
Treatment site explained more of the variation in ADHD treatment provision than patient factors. Higher ADHD symptom severity and sobriety at intake were associated with receiving ADHD treatment.
Christoffer Brynte, Arnt Schellekens, Csaba Barta, et al
PCC
Original Research
Evolution of Treatment Modalities for PTSD
December 12, 2024
The authors provide a bibliometric analysis of the most-cited articles published from 1990 to 2020 on evidence-based treatment modalities for PTSD to highlight significant developments in its understanding and management.
Mohsan Ali, Bisal Naseer, Muhammad T. Siddal, et al
JCP
Original Research
Long-Term Safety and Treatment Effect of Olanzapine/Samidorphan
December 4, 2024
During up to 4 years of treatment, the combination of olanzapine/samidorphan was safe and well-tolerated, and patients’ symptoms remained stable.
Jacob S. Ballon, René S. Kahn, Christina Arevalo, et al
JCP
Original Research
Sex Differences in Antidepressant Acceptability
December 4, 2024
This study provides evidence of sex differences in antidepressant acceptability, with fluoxetine more acceptable for men than women and the reverse true for paroxetine. Findings suggest the importance of...
Charles Ouazana Vedrines, Nicolas Hoertel, Thomas Lesuffleur, et al
PCC
Original Research
Intervention to Enhance Mental Health Competency
December 3, 2024
This study evaluated a novel curriculum aimed to increase non-psychiatry providers’ confidence in treating mental health conditions.
Maxwell F. Lydiatt, William M. Lydiatt, John C. Mitchell II, et al
JCP
Original Research
PTSD and Risk of Suicide Reattempt
November 25, 2024
After controlling for comorbid psychiatric conditions and other variables, PTSD was associated with suicide reattempt at 6 months (OR= 2.33) and with rehospitalization in psychiatric settings (OR=2.24) and nonpsychiatric...
Alice Demesmaeker, Fabien D’Hondt, Ali Amad, et al
JCP
Original Research
MDD and Bipolar Disorder in Black and White Postpartum Women
November 20, 2024
No significant difference was observed in the rate of postpartum MDD in Black (40%) versus white (35%) women. However, bipolar disorder significantly differed between Black (19.2%) and white (11.5%)...
Taylor N. Burchfield, Amy Yang, Katherine L. Wisner, et al
JCP
Original Research
Hyperbaric Oxygen Therapy for Combat-Associated PTSD
November 10, 2024
Hyperbaric oxygen therapy demonstrated significant improvements on measures of depression in male veterans with combat-associated PTSD.
Keren Doenyas-Barak, Ilan Kutz, Erez Lang, et al
PCC
Original Research
Psychiatric Comorbidities in Adolescents With Polycystic Ovary Syndrome
November 7, 2024
PCOS symptoms extend beyond reproductive issues, with noted correlations to anxiety, depression, and suicidal attempts. This study assessed psychiatric comorbidities among hospitalized adolescent females with PCOS.
Chintan Trivedi, Abid Rizvi, Sahar Ashraf, et al
JCP
Original Research
Mixed Features and Suicide Risk in Individuals With Major Depressive Episode
November 6, 2024
In a large sample of the French population, mixed features were linked to a higher risk of suicide attempts in patients with a major depressive episode.
Hugo Peyre, Nicolas Hoertel, Baptiste Pignon, et al
JCP
Original Research
History of Concussion and Maternal Mental Illness Risk
November 4, 2024
Individuals with a history of concussion had an increased risk of severe maternal mental illness; the association was strongest in those with no history of mental illness.
Samantha Krueger, Simone N. Vigod, Vincy Chan, et al
JCP
Original Research
Opioid Use Disorder Treatment in Sexually and Gender Diverse Patients
October 30, 2024
The disparities in buprenorphine prescriptions and in outpatient medical visit access between sexually and gender diverse (SGD) and non-SGD cohorts found in this study highlight priorities for culturally responsive...
Michal J. McDowell, Amitai S. Miller, Dana S. King, et al
JCP
Original Research
Suicide Crisis Syndrome Assessment and ED Readmission
October 23, 2024
Diagnosis of suicide crisis syndrome reduced readmission risk by approximately 72% for any reason and almost 75% for suicidal presentations.
Lisa J. Cohen, Betsy J. White, Fred E. Miller, et al
JCP
Original Research
Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans
October 23, 2024
Subthreshold PTSD affects 3.5% of US military veterans and is associated with increased rates of psychiatric disorders, suicidal thoughts and behaviors, and functional difficulties.
Ian C. Fischer, Peter J. Na, Ilan Harpaz-Rotem, et al
JCP
Original Research
Symptomatic Remission and Overall Recovery From BPD
October 23, 2024
Over 24 years, patients with BPD were significantly slower to achieve remission or recovery than patients with other personality disorders. Ultimately, however, both groups achieved similarly high rates of...
Mary C. Zanarini, Frances R. Frankenburg, Katherine E. Hein, et al
PCC
Original Research
Psychological Resilience of Mental Health Workers During the Russia-Ukraine War
October 22, 2024
Interventions that bolster social connectedness, meaning in life, and optimism may help promote psychological resilience among mental health workers exposed to ongoing war-related and work-related stressors.
Hun Kang, Ian C. Fischer, Viktor Vus, et al
JCP
Original Research
Gepirone-ER and Sexual Function in Patients with MDD
October 21, 2024
Rates of sexual side effects and treatment-emergent sexual dysfunction with gepirone-ER were similar to placebo and lower than sexual side effects reported for SSRIs.
Tierney K. Lorenz, Mary F. Johnson, Anita H. Clayton
JCP
Original Research
Fluctuating ADHD in the Multimodal Treatment of ADHD (MTA) Study
October 16, 2024
This study demonstrates that ADHD fluctuations are common and substantive and that, when remitted, individuals with fluctuating ADHD can successfully manage increased responsibilities.
Margaret H. Sibley, Traci M. Kennedy, James M. Swanson, et al
JCP
Original Research
Ketamine/Esketamine in Bipolar Depression in a Clinical Setting
October 2, 2024
In a small sample of patients with bipolar depression treated with ketamine/esketamine, no evidence of mania or hypomania was seen during acute treatment.
Mia C. Santucci, Mina Ansari, Sina Nikayin, et al
JCP
Original Research
Suicide Risk Evaluation and Advanced AI Models
October 2, 2024
This study explored how ChatGPT-3.5 and ChatGPT-4 assess suicide risk factors like previous attempts, gender, and age, focusing on their predictions about different types of suicidal behavior.
Shiri Shinan-Altman, Zohar Elyoseph, Inbar Levkovich
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