| dbo:abstract |
6-Chloronicotine is a drug which acts as an agonist at neural nicotinic acetylcholine receptors. It substitutes for nicotine in animal studies with around twice the potency, and shows antinociceptive effects. (en) 6-氯烟碱是一种有机化合物，化学式为C10H13ClN2。它可由烟碱经过氧化氢氧化，得N-氧化烟碱，加入三氯氧磷后反应制得，副产物2-氯烟碱可以通过加入二异丙胺抑制产生（<1%）。烟碱在−78 °C和正丁基锂反应，再和六氯乙烷反应也可以得到6-氯烟碱。它和正丁醇在碳酸铯和催化剂的存在下于甲苯中反应，可以得到6-丁氧基烟碱。 (zh) |
| dbo:casNumber |
112091-17-5 |
| dbo:pubchem |
10631771 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/(S)-6-Chloronicotine.svg?width=300 |
| dbo:wikiPageID |
66387301 (xsd:integer) |
| dbo:wikiPageLength |
2951 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1096600619 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbc:Pyrrolidines dbr:Epibatidine dbr:ABT-418 dbr:Agonist dbr:Altinicline dbr:Nicotine dbc:Chloropyridines dbc:Nicotinic_agonists dbr:Tebanicline dbr:Nicotinic_acetylcholine_receptor dbr:Antinociceptive |
| dbp:c |
10 (xsd:integer) |
| dbp:casNumber |
112091 (xsd:integer) |
| dbp:chemspiderid |
8807133 (xsd:integer) |
| dbp:cl |
1 (xsd:integer) |
| dbp:h |
13 (xsd:integer) |
| dbp:iupacName |
2 (xsd:integer) |
| dbp:n |
2 (xsd:integer) |
| dbp:pubchem |
10631771 (xsd:integer) |
| dbp:smiles |
CN1CCC[C@H]1C2=CN=CCl (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
SVVOLGNZRGLPIU-VIFPVBQESA-N (en) |
| dbp:width |
200 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Pharm-stub dbt:Reflist dbt:Context dbt:Nicotinic_acetylcholine_receptor_modulators |
| dct:subject |
dbc:Pyrrolidines dbc:Chloropyridines dbc:Nicotinic_agonists |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment |
6-Chloronicotine is a drug which acts as an agonist at neural nicotinic acetylcholine receptors. It substitutes for nicotine in animal studies with around twice the potency, and shows antinociceptive effects. (en) 6-氯烟碱是一种有机化合物，化学式为C10H13ClN2。它可由烟碱经过氧化氢氧化，得N-氧化烟碱，加入三氯氧磷后反应制得，副产物2-氯烟碱可以通过加入二异丙胺抑制产生（<1%）。烟碱在−78 °C和正丁基锂反应，再和六氯乙烷反应也可以得到6-氯烟碱。它和正丁醇在碳酸铯和催化剂的存在下于甲苯中反应，可以得到6-丁氧基烟碱。 (zh) |
| rdfs:label |
6-Chloronicotine (en) 6-氯烟碱 (zh) |
| owl:sameAs |
wikidata:6-Chloronicotine https://global.dbpedia.org/id/FLWub dbpedia-zh:6-Chloronicotine |
| prov:wasDerivedFrom |
wikipedia-en:6-Chloronicotine?oldid=1096600619&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/(S)-6-Chloronicotine.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:6-Chloronicotine |
| is dbo:wikiPageWikiLink of |
dbr:Epibatidine dbr:Nicotine |
| is foaf:primaryTopic of |
wikipedia-en:6-Chloronicotine |
