BBSome (original) (raw)
The BBSome is an octameric protein complex. It is a component of the basal body and is involved in trafficking cargos to the primary cilium. The BBSome is a complex of seven Bardet–Biedl syndrome (BBS) proteins: BBS1, BBS2, BBS4, BBS5, BBS7, BBS8 and BBS9. In addition the BBSome contains the protein. Mutation in each of this eight BBSome genes (as well as other 14 BBS genes identified to date ) causes a severe multiorganic syndrome (BBS) presenting in most cases by retinal dystrophy, obesity, renal anomalies, post-axial polydactyly, and developmental delay.
| Property | Value |
|---|---|
| dbo:abstract | The BBSome is an octameric protein complex. It is a component of the basal body and is involved in trafficking cargos to the primary cilium. The BBSome is a complex of seven Bardet–Biedl syndrome (BBS) proteins: BBS1, BBS2, BBS4, BBS5, BBS7, BBS8 and BBS9. In addition the BBSome contains the protein. Mutation in each of this eight BBSome genes (as well as other 14 BBS genes identified to date ) causes a severe multiorganic syndrome (BBS) presenting in most cases by retinal dystrophy, obesity, renal anomalies, post-axial polydactyly, and developmental delay. (en) BBSome ist ein Proteinkomplex, welcher den Zilien neue Proteine zuführt und im eine wichtige Rolle spielt. Entdeckt wurde der Komplex in 2007. (de) |
| dbo:wikiPageID | 29751466 (xsd:integer) |
| dbo:wikiPageLength | 3670 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1039890399 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:BBS1 dbr:BBS10 dbr:BBS12 dbr:BBS2 dbr:BBS4 dbr:BBS5 dbr:BBS7 dbr:BBS9 dbr:Primary_cilium dbr:Bardet–Biedl_syndrome dbr:Basal_body dbc:Organelles dbr:BBS6 dbr:BBS8 dbr:BBIP10 |
| dbp:wikiPageUsesTemplate | dbt:Reflist dbt:Ciliary_proteins dbt:Cell-biology-stub |
| dcterms:subject | dbc:Organelles |
| gold:hypernym | dbr:Component |
| rdf:type | yago:WikicatOrganelles yago:BodyPart105220461 yago:Organ105297523 yago:Organelle105445668 yago:Part109385911 yago:PhysicalEntity100001930 dbo:MilitaryUnit yago:Thing100002452 |
| rdfs:comment | The BBSome is an octameric protein complex. It is a component of the basal body and is involved in trafficking cargos to the primary cilium. The BBSome is a complex of seven Bardet–Biedl syndrome (BBS) proteins: BBS1, BBS2, BBS4, BBS5, BBS7, BBS8 and BBS9. In addition the BBSome contains the protein. Mutation in each of this eight BBSome genes (as well as other 14 BBS genes identified to date ) causes a severe multiorganic syndrome (BBS) presenting in most cases by retinal dystrophy, obesity, renal anomalies, post-axial polydactyly, and developmental delay. (en) BBSome ist ein Proteinkomplex, welcher den Zilien neue Proteine zuführt und im eine wichtige Rolle spielt. Entdeckt wurde der Komplex in 2007. (de) |
| rdfs:label | BBSome (de) BBSome (en) |
| owl:sameAs | freebase:BBSome yago-res:BBSome wikidata:BBSome dbpedia-de:BBSome https://global.dbpedia.org/id/4Um28 |
| prov:wasDerivedFrom | wikipedia-en:BBSome?oldid=1039890399&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:BBSome |
| is dbo:wikiPageRedirects of | dbr:BBsome |
| is dbo:wikiPageWikiLink of | dbr:BBS1 dbr:BBsome dbr:RVxP_motif dbr:Alström_syndrome dbr:Coiled_coil |
| is foaf:primaryTopic of | wikipedia-en:BBSome |