Caveolin 2 (original) (raw)
Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.
| Property | Value |
|---|---|
| dbo:abstract | Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript. (en) |
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| dbo:wikiPageLength | 10196 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1040416999 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Protein-protein_interaction dbr:List_of_heliports_in_Canada dbr:RAS_p21_protein_activator_1 dbr:Gene dbr:Apoptosis dbr:Tumor_suppressor dbr:Caveolae dbr:Caveolin_1 dbr:Chromosome_7 dbr:Protein dbr:2nd_Cavalry_(disambiguation) dbr:Codons |
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| gold:hypernym | dbr:Protein |
| rdf:type | owl:Thing dbo:Biomolecule dbo:Gene wikidata:Q206229 wikidata:Q7187 dbo:HumanGene dbo:Protein umbel-rc:ProteinMolecule |
| rdfs:comment | Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript. (en) |
| rdfs:label | Caveolin 2 (en) |
| owl:sameAs | freebase:Caveolin 2 wikidata:Caveolin 2 dbpedia-fa:Caveolin 2 https://global.dbpedia.org/id/zcPX |
| prov:wasDerivedFrom | wikipedia-en:Caveolin_2?oldid=1040416999&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Caveolin_2 |
| is dbo:wikiPageRedirects of | dbr:CAV2_(gene) dbr:CAV2 |
| is dbo:wikiPageWikiLink of | dbr:Endocytosis dbr:CAV2_(gene) dbr:Inflammatory_breast_cancer dbr:RAS_p21_protein_activator_1 dbr:Caveolin dbr:Caveolin_1 dbr:List_of_MeSH_codes_(D12.644) dbr:List_of_MeSH_codes_(D12.776) dbr:List_of_MeSH_codes_(D12.776.476) dbr:List_of_MeSH_codes_(D12.776.543) dbr:CAV2 dbr:Tyrosine_phosphorylation |
| is dbp:name of | dbr:Caveolin |
| is dbp:symbol of | dbr:Caveolin |
| is foaf:primaryTopic of | wikipedia-en:Caveolin_2 |