Chitinase domain-containing protein 1 (original) (raw)
Chitinase domain-containing protein 1 (CHID1) is a highly conserved protein of unknown function located on the short (p) arm of chromosome 11 near the telomere. The protein has 27 introns, which allows for many isoforms of this gene. It has several aliases, the most common of which is Stabilin-1 interacting chitinase-like protein (SI-CLP). As indicated by the alias, CHID1 is known to interact with the protein STAB1. CHID1 is expressed ubiquitously at levels nearly 6 times the average gene, and is conserved very far back to organisms such as Caenorhabditis elegans and possibly some prokaryotes. This protein is known to have carbohydrate binding sites, which could be involved in carbohydrate catabolysis.
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dbo:abstract | Chitinase domain-containing protein 1 (CHID1) is a highly conserved protein of unknown function located on the short (p) arm of chromosome 11 near the telomere. The protein has 27 introns, which allows for many isoforms of this gene. It has several aliases, the most common of which is Stabilin-1 interacting chitinase-like protein (SI-CLP). As indicated by the alias, CHID1 is known to interact with the protein STAB1. CHID1 is expressed ubiquitously at levels nearly 6 times the average gene, and is conserved very far back to organisms such as Caenorhabditis elegans and possibly some prokaryotes. This protein is known to have carbohydrate binding sites, which could be involved in carbohydrate catabolysis. (en) CHID1 (англ. Chitinase domain containing 1) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 11-ї хромосоми. Довжина поліпептидного ланцюга білка становить 393 амінокислот, а молекулярна маса — 44 941. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Задіяний у таких біологічних процесах, як імунітет, вроджений імунітет, альтернативний сплайсинг. Локалізований у лізосомі.Також секретований назовні. (uk) |
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dbo:wikiPageWikiLink | dbr:Caenorhabditis_elegans dbr:Carbohydrate dbr:Prokaryote dbr:Cytoplasm dbr:DNA_microarray dbr:In_vitro dbr:In_vivo dbr:Intron dbr:Conserved_sequence dbr:Protein_domains dbr:Alpha_helices dbr:Lysosomes dbr:Chitin dbr:Drosophila_melanogaster dbr:STAB1 dbr:Exons dbr:Angiogenesis dbr:Carbohydrate-binding_module dbr:Carbohydrate_catabolism dbr:Chromosome dbr:Chromosome_11 dbr:Glycoside_hydrolase_family_18 dbr:File:CHID1_Multiple_Sequence_Alignment.png dbr:File:CHID1_barrel.png dbr:File:CHID1_geo_profile.png dbr:File:CHID1phylogeny.png dbr:Transcription_factor dbr:Isoform dbr:AP2A2 dbr:Telomere dbr:Assays dbr:Sulfate dbr:Metabolism dbr:Catabolism dbr:X-ray_crystallography dbr:In_situ_hybridization dbr:Two-hybrid_screening dbr:TSPAN4 dbr:Transmembrane dbr:Superfamily_(molecular_biology) dbr:Post-translational dbr:Beta_actin dbr:Beta_strand dbr:Homodimer |
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rdfs:comment | Chitinase domain-containing protein 1 (CHID1) is a highly conserved protein of unknown function located on the short (p) arm of chromosome 11 near the telomere. The protein has 27 introns, which allows for many isoforms of this gene. It has several aliases, the most common of which is Stabilin-1 interacting chitinase-like protein (SI-CLP). As indicated by the alias, CHID1 is known to interact with the protein STAB1. CHID1 is expressed ubiquitously at levels nearly 6 times the average gene, and is conserved very far back to organisms such as Caenorhabditis elegans and possibly some prokaryotes. This protein is known to have carbohydrate binding sites, which could be involved in carbohydrate catabolysis. (en) CHID1 (англ. Chitinase domain containing 1) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 11-ї хромосоми. Довжина поліпептидного ланцюга білка становить 393 амінокислот, а молекулярна маса — 44 941. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk) |
rdfs:label | Chitinase domain-containing protein 1 (en) CHID1 (uk) |
owl:sameAs | freebase:Chitinase domain-containing protein 1 wikidata:Chitinase domain-containing protein 1 http://tt.dbpedia.org/resource/CHID1 dbpedia-uk:Chitinase domain-containing protein 1 https://global.dbpedia.org/id/jZkj |
prov:wasDerivedFrom | wikipedia-en:Chitinase_domain-containing_protein_1?oldid=1116713383&ns=0 |
foaf:depiction | wiki-commons:Special:FilePath/CHID1_Multiple_Sequence_Alignment.png wiki-commons:Special:FilePath/CHID1_barrel.png wiki-commons:Special:FilePath/CHID1_geo_profile.png wiki-commons:Special:FilePath/CHID1phylogeny.png |
foaf:isPrimaryTopicOf | wikipedia-en:Chitinase_domain-containing_protein_1 |
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is foaf:primaryTopic of | wikipedia-en:Chitinase_domain-containing_protein_1 |