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لا يجب الخلط بينه وبين دراسات الترجمة. يستخدم البحث الانتقالي غالبًا بالتبادل مع الطب الترجمي أو علوم الترجمة أو البحوث منضدية سريرية - هو محاولة للبناء على البحث العلمي الأساسي لإنشاء علاجات جديدة، الإجراءات الطبية، أو التشخيص. تعتمد البحوث الطبية الحيوية الأساسية على دراسات لعمليات المرض باستخدام الثقافات الخلوية أو النماذج الحيوانية على سبيل المثال. يشير المصطلح الانتقالي إلى «ترجمة» النتائج العلمية الأساسية في بيئة معملية إلى علاجات محتملة للأمراض. (ar) 橋渡し研究（はしわたしけんきゅう、英: translational research）とは、主に医学や生物学における基礎研究の成果の中から有望な知見を選び出し、通常の医薬品や医療機器の開発に要する試験物製造から臨床研究に至るまでの工程を一体的に捉えた開発戦略を策定することにより、効率的･効果的に医療としての実用化につなげることを目的とする医学研究の一領域である。 (ja) Translational research (also called translation research, translational science, or, when the context is clear, simply translation) is research aimed at translating (converting) results in basic research into results that directly benefit humans. The term is used in science and technology, especially in biology and medical science. As such, translational research forms a subset of applied research. The term has been used most commonly in life-sciences and biotechnology but applies across the spectrum of science and humanities. In the context of biomedicine, translational research is also known as bench to bedside. In the field of education, it is defined as research which translates concepts to classroom practice. Critics of translational medical research (to the exclusion of more basic research) point to examples of important drugs that arose from fortuitous discoveries in the course of basic research such as penicillin and benzodiazepines. Other problems have stemmed from the widespread irreproducibility thought to exist in translational research literature. Although translational research is relatively new, there are now several major research centers focused on it. In the U.S., the National Institutes of Health has implemented a major national initiative to leverage existing academic health center infrastructure through the Clinical and Translational Science Awards. Furthermore, some universities acknowledge translational research as its own field to study for a PhD or graduate certificate in. (en) Translationell forskning (från latinets translatio=överföring) är en skola för medicinsk forskning som bygger på att problem som upptäcks i sjukvården, exempelvis vid diagnos eller pågående behandling, används i utveckling och forskning innan klinisk prövning. Forskningen utgår därmed från en patients hälsosituation och har som målsättning att snabbt uppnå resultat som kan leda till bättre diagnostik och terapi för patienten. Arbetssättet är inte nytt, men begreppet började användas först under 2000-talet. Tillämpningen av upptäckter genererade i laboratorieforskning och prekliniska studier på utvecklingen av kliniska prövningar och studier på människor. Ett andra område i translationell forskning handlar om att förbättra och utveckla ”best practices” – bästa fungerande praxis. Vetenskapliga tidskrifter med inriktning translationell forskning har skapats, Science Translational Medicine och Journal of Translational Medicine. Mer läsning: Varför translationell forskning är så viktig och “What is Translational Research?” (sv) |
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لا يجب الخلط بينه وبين دراسات الترجمة. يستخدم البحث الانتقالي غالبًا بالتبادل مع الطب الترجمي أو علوم الترجمة أو البحوث منضدية سريرية - هو محاولة للبناء على البحث العلمي الأساسي لإنشاء علاجات جديدة، الإجراءات الطبية، أو التشخيص. تعتمد البحوث الطبية الحيوية الأساسية على دراسات لعمليات المرض باستخدام الثقافات الخلوية أو النماذج الحيوانية على سبيل المثال. يشير المصطلح الانتقالي إلى «ترجمة» النتائج العلمية الأساسية في بيئة معملية إلى علاجات محتملة للأمراض. (ar) 橋渡し研究（はしわたしけんきゅう、英: translational research）とは、主に医学や生物学における基礎研究の成果の中から有望な知見を選び出し、通常の医薬品や医療機器の開発に要する試験物製造から臨床研究に至るまでの工程を一体的に捉えた開発戦略を策定することにより、効率的･効果的に医療としての実用化につなげることを目的とする医学研究の一領域である。 (ja) Translational research (also called translation research, translational science, or, when the context is clear, simply translation) is research aimed at translating (converting) results in basic research into results that directly benefit humans. The term is used in science and technology, especially in biology and medical science. As such, translational research forms a subset of applied research. (en) Translationell forskning (från latinets translatio=överföring) är en skola för medicinsk forskning som bygger på att problem som upptäcks i sjukvården, exempelvis vid diagnos eller pågående behandling, används i utveckling och forskning innan klinisk prövning. Forskningen utgår därmed från en patients hälsosituation och har som målsättning att snabbt uppnå resultat som kan leda till bättre diagnostik och terapi för patienten. Arbetssättet är inte nytt, men begreppet började användas först under 2000-talet. (sv) |
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