DCL1 (original) (raw)
DCL1 (an abbreviation of Dicer-like 1) is a gene in plants that codes for the DCL1 protein, a ribonuclease III enzyme involved in processing double-stranded RNA (dsRNA) and microRNA (miRNA). Although DCL1, also called Endoribonuclease Dicer homolog 1, is named for its homology with the metazoan protein Dicer, its role in miRNA biogenesis is somewhat different, due to substantial differences in miRNA maturation processes between plants and animals, as well due to additional downstream plant-specific pathways, where DCL1 paralogs like DCL4 participate, such Trans-acting siRNA biogenesis.
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| Property | Value |
|---|---|
| dbo:abstract | DCL1 (an abbreviation of Dicer-like 1) is a gene in plants that codes for the DCL1 protein, a ribonuclease III enzyme involved in processing double-stranded RNA (dsRNA) and microRNA (miRNA). Although DCL1, also called Endoribonuclease Dicer homolog 1, is named for its homology with the metazoan protein Dicer, its role in miRNA biogenesis is somewhat different, due to substantial differences in miRNA maturation processes between plants and animals, as well due to additional downstream plant-specific pathways, where DCL1 paralogs like DCL4 participate, such Trans-acting siRNA biogenesis. (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Cartoon_representatio..._al._Nat._Plants._2021).gif?width=300 |
| dbo:wikiPageExternalLink | https://www.rcsb.org/structure/7ELD https://www.rcsb.org/structure/7ELE |
| dbo:wikiPageID | 49466391 (xsd:integer) |
| dbo:wikiPageLength | 9065 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1120843580 (xsd:integer) |
| dbo:wikiPageWikiLink | dbc:Ribonucleases dbr:MicroRNA dbr:Brassicaceae dbr:Ribonuclease_III dbr:Cytoplasm dbr:DCL2 dbr:DCL3 dbr:Enzyme dbr:Gene dbr:Microprocessor_complex dbr:Drosha dbr:Cell_nucleus dbr:Dicer dbr:Protein dbr:Trans-acting_siRNA dbc:Plant_proteins dbr:Homology_(biology) dbr:Plant dbr:Populus_trichocarpa dbr:Metazoan dbr:RNA-binding_protein dbr:Paralog dbr:Double-stranded_RNA dbr:Primary_miRNA dbr:DCL4 dbr:DCL5 dbr:File:DCL1-HYL-SE-CARP9_scaffolding_and_miRNA_maturation_in_plants.jpg dbr:HYL1 dbr:SERRATE |
| dbp:altsymbols | AT1G01040 (en) |
| dbp:caption | Cartoon representation of Arabidopsis DCL1 in complex with pri-miRNA 166f. Single chain of DCL1 in light purple catalyzing the cleavage of pri-miRNA-166f into pre-miRNA-166f, before one more cleavage step to finally release miRNA-166f. (en) |
| dbp:chromosome | 1 (xsd:integer) |
| dbp:ecnumber | EC:3.1.26 (en) |
| dbp:genlocEnd | 31120 (xsd:integer) |
| dbp:genlocStart | 23416 (xsd:integer) |
| dbp:name | Endoribonuclease Dicer homolog 1 (en) |
| dbp:organism | Arabidopsis thaliana (en) |
| dbp:pdb | 7 (xsd:integer) |
| dbp:symbol | DCL1 (en) |
| dbp:taxid | 3702 (xsd:integer) |
| dbp:uniprot | Q9SP32 (en) |
| dbp:wikiPageUsesTemplate | dbt:Infobox_nonhuman_protein dbt:Protein-stub dbt:Reflist |
| dct:subject | dbc:Ribonucleases dbc:Plant_proteins |
| gold:hypernym | dbr:Gene |
| rdf:type | dbo:Protein |
| rdfs:comment | DCL1 (an abbreviation of Dicer-like 1) is a gene in plants that codes for the DCL1 protein, a ribonuclease III enzyme involved in processing double-stranded RNA (dsRNA) and microRNA (miRNA). Although DCL1, also called Endoribonuclease Dicer homolog 1, is named for its homology with the metazoan protein Dicer, its role in miRNA biogenesis is somewhat different, due to substantial differences in miRNA maturation processes between plants and animals, as well due to additional downstream plant-specific pathways, where DCL1 paralogs like DCL4 participate, such Trans-acting siRNA biogenesis. (en) |
| rdfs:label | DCL1 (en) |
| owl:sameAs | freebase:DCL1 yago-res:DCL1 wikidata:DCL1 https://global.dbpedia.org/id/2d4wS |
| prov:wasDerivedFrom | wikipedia-en:DCL1?oldid=1120843580&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Cartoon_representatio..._Wei_X._et_al._Nat._Plants._2021).gif wiki-commons:Special:FilePath/DCL1-HYL-SE-CARP9_sca...ng_and_miRNA_maturation_in_plants.jpg |
| foaf:isPrimaryTopicOf | wikipedia-en:DCL1 |
| is dbo:wikiPageRedirects of | dbr:DICER-like dbr:Dicer-like1 dbr:Dicer-like_1 |
| is dbo:wikiPageWikiLink of | dbr:Animesh_Ray dbr:DCL2 dbr:DCL3 dbr:Microprocessor_complex dbr:DICER-like dbr:Piwi-interacting_RNA dbr:RNA-directed_DNA_methylation dbr:Dicer-like1 dbr:Dicer-like_1 |
| is foaf:primaryTopic of | wikipedia-en:DCL1 |
