Fibroblast growth factor receptor (original) (raw)

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The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. Some of these receptors are involved in pathological conditions. For example, a point mutation in FGFR3 can lead to achondroplasia.

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dbo:abstract The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. Some of these receptors are involved in pathological conditions. For example, a point mutation in FGFR3 can lead to achondroplasia. (en) Los receptores del factor de crecimiento fibroblástico o FGF-R (acrónimo de Fibroblast Growth Factor Receptor) se encuentran en el espesor de las membranas celulares y se unen de forma específica al factor de crecimiento de fibroblastos permitiéndole realizar su función. Pertenece a la superfamilia de receptores que presentan actividad tirosina quinasa intrínseca. Existen varios subtipos. Las mutaciones que alteran la estructura proteica de estos receptores pueden provocar enfermedad, por ejemplo la acondroplasia está causada por una mutación que altera el FGF-R3.​ ​ ​ (es) Les FGFR (pour « fibroblast growth factor receptors ») sont des récepteurs qui fixent les différents facteurs de croissance des fibroblastes, permettant leurs actions. (fr) 線維芽細胞増殖因子受容体（せんいがさいぼうぞうしょくいんしじゅようたい、fibroblast growth factor receptors，FGFR）は、線維芽細胞増殖因子（FGF）ファミリーのタンパク質に結合する受容体である。これらの中には疾患に関与するものがあり、例えばの点突然変異は軟骨無形成症を引き起こす可能性がある。 (ja) Рецепторы фактора роста фибробластов (англ. Fibroblast growth factor receptors; FGFR) — семейство мембранных белков, класс рецепторных тирозинкиназ, которые связываются с членами семейства факторов роста фибробластов. Мутации этих рецепторов часто приводят к нарушениям, таким как ахондроплазия. (ru) 成纤维细胞生长因子受体（英語：fibroblast growth factor receptors，FGFR）是一类与成纤维细胞生长因子结合的受体蛋白质家族，正如其名字所暗示的。这类受体涉及了一些病理条件。例如，上的一个位点突变可导致軟骨發育不全症。 (zh)
dbo:symbol FGFR
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dbp:symbol FGFR (en)
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rdfs:comment The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. Some of these receptors are involved in pathological conditions. For example, a point mutation in FGFR3 can lead to achondroplasia. (en) Los receptores del factor de crecimiento fibroblástico o FGF-R (acrónimo de Fibroblast Growth Factor Receptor) se encuentran en el espesor de las membranas celulares y se unen de forma específica al factor de crecimiento de fibroblastos permitiéndole realizar su función. Pertenece a la superfamilia de receptores que presentan actividad tirosina quinasa intrínseca. Existen varios subtipos. Las mutaciones que alteran la estructura proteica de estos receptores pueden provocar enfermedad, por ejemplo la acondroplasia está causada por una mutación que altera el FGF-R3.​ ​ ​ (es) Les FGFR (pour « fibroblast growth factor receptors ») sont des récepteurs qui fixent les différents facteurs de croissance des fibroblastes, permettant leurs actions. (fr) 線維芽細胞増殖因子受容体（せんいがさいぼうぞうしょくいんしじゅようたい、fibroblast growth factor receptors，FGFR）は、線維芽細胞増殖因子（FGF）ファミリーのタンパク質に結合する受容体である。これらの中には疾患に関与するものがあり、例えばの点突然変異は軟骨無形成症を引き起こす可能性がある。 (ja) Рецепторы фактора роста фибробластов (англ. Fibroblast growth factor receptors; FGFR) — семейство мембранных белков, класс рецепторных тирозинкиназ, которые связываются с членами семейства факторов роста фибробластов. Мутации этих рецепторов часто приводят к нарушениям, таким как ахондроплазия. (ru) 成纤维细胞生长因子受体（英語：fibroblast growth factor receptors，FGFR）是一类与成纤维细胞生长因子结合的受体蛋白质家族，正如其名字所暗示的。这类受体涉及了一些病理条件。例如，上的一个位点突变可导致軟骨發育不全症。 (zh)
rdfs:label Fibroblast growth factor receptor (en) Receptor del factor de crecimiento fibroblástico (es) FGFR (fr) 線維芽細胞増殖因子受容体 (ja) Рецепторы фактора роста фибробластов (ru) 成纤维细胞生长因子受体 (zh)
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