| dbo:abstract |
Frizzled receptor je receptor spřažený s G-proteinem pro Wnt signálizaci a další signální dráhy u hub a zvířat. Pokud je aktivován, Frizzled vede k aktivaci proteinů Disevelled v cytosolu. (cs) Frizzled is a family of atypical G protein-coupled receptors that serve as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled in the cytosol. (en) Frizzled es una familia de proteínas de Receptores acoplados a proteínas G, que sirve como receptor en la y otras rutas de señalización. Cuando se activa, Frizzled produce la activación de la proteína en el citosol. (es) Les protéines transmembranaires Frizzled (Fz) sont une famille de récepteurs couplés aux protéines G (RCPG) qui tiennent notamment un rôle dans la voie de signalisation Wnt. L’activation du récepteur conduit à l’activation de la protéine Dishevelled dans le cytosol. (fr) Frizzled（Fz）は非典型的Gタンパク質共役受容体のファミリーであり、Wntシグナル経路や他のシグナル伝達経路の受容体として機能する。Frizzledが活性化された際には、細胞質基質に位置するDishevelledが活性化される。 (ja) 卷曲受体（英語：Frizzled）是G蛋白偶联受体中的一个家族作为Wnt信号通路和其他信号通路中的受体。当其被激活，会引起基质中信号通路下游散乱蛋白的激活。 (zh) |
| dbo:symbol |
Frizzled |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Frizzled.png?width=300 |
| dbo:wikiPageExternalLink |
http://www.iuphar-db.org/GPCR/ChapterMenuForward%3FchapterID=1504 |
| dbo:wikiPageID |
10033072 (xsd:integer) |
| dbo:wikiPageLength |
7407 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1047585547 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Cancer dbr:Cytosol dbr:Vantictumab dbr:Vitreous_humour dbr:Monoclonal_antibody dbr:Receptor_tyrosine_kinases dbr:Drosophila_melanogaster dbr:G_protein-coupled_receptor dbr:Drosophila dbr:FZD1 dbr:FZD10 dbr:FZD2 dbr:FZD3 dbr:FZD4 dbr:FZD5 dbr:FZD6 dbr:FZD7 dbr:FZD8 dbr:FZD9 dbr:Familial_exudative_vitreoretinopathy dbc:G_protein-coupled_receptors dbr:Synapses dbr:Dishevelled dbr:Smoothened dbr:Wnt_signaling_pathway dbr:File:Signal_transduction_pathways.svg |
| dbp:caption |
Crystal structure of the cysteine-rich domain of mouse frizzled 8 (en) |
| dbp:cdd |
cd13951 (en) |
| dbp:interpro |
IPR000539 (en) |
| dbp:name |
Frizzled/Smoothened family membrane region (en) |
| dbp:opmFamily |
6 (xsd:integer) |
| dbp:opmProtein |
4 (xsd:integer) |
| dbp:pfam |
PF01534 (en) |
| dbp:pfamClan |
GPCR_A (en) |
| dbp:prosite |
PDOC50038 (en) |
| dbp:symbol |
Frizzled (en) |
| dbp:tcdb |
9 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:G_protein-coupled_receptors dbt:Cite_web dbt:Gene dbt:MeshName dbt:Other_uses dbt:Reflist dbt:Short_description dbt:InterPro dbt:Wnt_signaling_pathway dbt:Pfam_box |
| dct:subject |
dbc:G_protein-coupled_receptors |
| gold:hypernym |
dbr:Family |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Protein yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatProteins |
| rdfs:comment |
Frizzled receptor je receptor spřažený s G-proteinem pro Wnt signálizaci a další signální dráhy u hub a zvířat. Pokud je aktivován, Frizzled vede k aktivaci proteinů Disevelled v cytosolu. (cs) Frizzled is a family of atypical G protein-coupled receptors that serve as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled in the cytosol. (en) Frizzled es una familia de proteínas de Receptores acoplados a proteínas G, que sirve como receptor en la y otras rutas de señalización. Cuando se activa, Frizzled produce la activación de la proteína en el citosol. (es) Les protéines transmembranaires Frizzled (Fz) sont une famille de récepteurs couplés aux protéines G (RCPG) qui tiennent notamment un rôle dans la voie de signalisation Wnt. L’activation du récepteur conduit à l’activation de la protéine Dishevelled dans le cytosol. (fr) Frizzled（Fz）は非典型的Gタンパク質共役受容体のファミリーであり、Wntシグナル経路や他のシグナル伝達経路の受容体として機能する。Frizzledが活性化された際には、細胞質基質に位置するDishevelledが活性化される。 (ja) 卷曲受体（英語：Frizzled）是G蛋白偶联受体中的一个家族作为Wnt信号通路和其他信号通路中的受体。当其被激活，会引起基质中信号通路下游散乱蛋白的激活。 (zh) |
| rdfs:label |
Frizzled receptor (cs) Frizzled (en) Frizzled (es) Frizzled (fr) Frizzled (ja) 卷曲受体 (zh) |
| owl:sameAs |
freebase:Frizzled yago-res:Frizzled wikidata:Frizzled dbpedia-cs:Frizzled dbpedia-es:Frizzled dbpedia-fa:Frizzled dbpedia-fr:Frizzled dbpedia-ja:Frizzled dbpedia-sh:Frizzled dbpedia-sr:Frizzled dbpedia-zh:Frizzled https://global.dbpedia.org/id/3sFqC |
| prov:wasDerivedFrom |
wikipedia-en:Frizzled?oldid=1047585547&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Signal_transduction_pathways.svg wiki-commons:Special:FilePath/Frizzled.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:Frizzled |
| is dbo:wikiPageDisambiguates of |
dbr:FRZ dbr:FZD dbr:Frizzle |
| is dbo:wikiPageRedirects of |
dbr:Frizzled_receptors |
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