Genistin (original) (raw)
Genistin is an isoflavone found in a number of dietary plants like soy and kudzu. It was first isolated in 1931 from the 90% methanol extract of a soybean meal, when it was found that hydrolysis with hydrochloric acid produced 1 mole each of genistein and glucose. Chemically it is the 7-O-beta-D-glucoside form of genistein and is the predominant form of the isoflavone naturally occurring in plants. In fact, studies in the 1970s revealed that 99% of the isoflavonoid compounds in soy are present as their glucosides. The glucosides are converted by digestive enzymes in the digestive system to exert their biological effects. Genistin is also converted to a more familiar genistein, thus, the biological activities including antiatherosclerotic, estrogenic and anticancer effects are analogous.
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|---|---|
| dbo:abstract | Genistin is an isoflavone found in a number of dietary plants like soy and kudzu. It was first isolated in 1931 from the 90% methanol extract of a soybean meal, when it was found that hydrolysis with hydrochloric acid produced 1 mole each of genistein and glucose. Chemically it is the 7-O-beta-D-glucoside form of genistein and is the predominant form of the isoflavone naturally occurring in plants. In fact, studies in the 1970s revealed that 99% of the isoflavonoid compounds in soy are present as their glucosides. The glucosides are converted by digestive enzymes in the digestive system to exert their biological effects. Genistin is also converted to a more familiar genistein, thus, the biological activities including antiatherosclerotic, estrogenic and anticancer effects are analogous. (en) Genistina es una isoflavona encontrada en un número de plantas dietéticas como la soja y el kudzu. Fue aislado por primera vez en 1931 a partir del extracto de metanol 90% de una comida de soja, cuando se encontró que la hidrólisis con ácido clorhídrico produce 1 mol cada uno de genisteína y glucosa. Químicamente es la 7-O-beta-D- glucósido forma de genisteína y es la forma predominante de la isoflavona de origen natural en las plantas. De hecho, estudios realizados en la década de 1970 revelaron que el 99% de los compuestos isoflavonoides de la soja están presentes como sus glucósidos. Los glucósidos son convertidos por las enzimas digestivas en el sistema digestivo para ejercer sus efectos biológicos. Genistina también se convierte en una genisteína más familiar, por lo tanto, las actividades biológicas incluyendo efectos antiateroscleróticos, estrogénicos y contra el cáncer son análogos (es) |
| dbo:alternativeName | Genistein 7-O-beta-D-glucoside (en) Genistein 7-glucoside (en) Genistein glucoside (en) Genistein-7-glucoside (en) Genisteol 7-monoglucoside (en) Genistine (en) Genistoside (en) Glucosyl-7-genistein (en) |
| dbo:iupacName | 5-Hydroxy-3-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-1-benzopyran-4-one (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Genistin.svg?width=300 |
| dbo:wikiPageExternalLink | http://www.chemicalbook.com/ChemicalProductProperty_EN_CB9769395.htm http://www.springerreference.com/docs/html/chapterdbid/351525.html https://web.archive.org/web/20140726143649/http:/www.wikigenes.org/e/chem/e/5281377.html |
| dbo:wikiPageID | 24106658 (xsd:integer) |
| dbo:wikiPageLength | 8237 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1059918655 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Calcium dbr:Cancer dbr:Mole_(unit) dbr:MCF-7 dbr:Bone dbr:Hydrochloric_acid dbc:Isoflavone_glucosides dbr:Small_intestine dbr:Estrogen dbr:Enzyme dbr:Genistein dbr:Glucose dbr:Liver dbr:Parts_per_million dbr:Aglycone dbr:Tumor dbr:Estrogenic dbr:Cell_proliferation dbr:Glucoside dbr:Isoflavone dbr:Isoflavonoid dbr:Rotavirus dbr:Covalent_bond dbr:Hydrolysis dbr:Collagen dbr:Tissue_culture dbr:Dna dbr:Soy dbr:Soybean dbr:Kudzu dbr:Metabolism dbr:Methanol dbr:Mice dbr:Rat dbr:Saliva dbr:New_Zealand_rabbit dbr:Digestive_enzymes dbr:Phosphatase dbr:Phytoestrogen dbr:Intestine dbr:Fructooligosaccharides dbr:Digestive_system dbr:Anticancer |
| dbp:imagefile | Genistin.svg (en) |
| dbp:imagesize | 300 (xsd:integer) |
| dbp:name | Genistin (en) |
| dbp:othernames | Genistein 7-O-beta-D-glucoside (en) Genistein 7-glucoside (en) Genistein glucoside (en) Genistein-7-glucoside (en) Genisteol 7-monoglucoside (en) Genistine (en) Genistoside (en) Glucosyl-7-genistein (en) |
| dbp:pin | 5 (xsd:integer) |
| dbp:verifiedrevid | 443833872 (xsd:integer) |
| dbp:watchedfields | changed (en) |
| dbp:wikiPageUsesTemplate | dbt:Isoflavone dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Distinguish dbt:PubChem dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite |
| dct:subject | dbc:Isoflavone_glucosides |
| gold:hypernym | dbr:Isoflavone |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Glucoside114887801 yago:Glycoside114887305 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 yago:WikicatIsoflavoneGlucosides dbo:ChemicalCompound yago:Substance100019613 umbel-rc:ChemicalSubstanceType |
| rdfs:comment | Genistin is an isoflavone found in a number of dietary plants like soy and kudzu. It was first isolated in 1931 from the 90% methanol extract of a soybean meal, when it was found that hydrolysis with hydrochloric acid produced 1 mole each of genistein and glucose. Chemically it is the 7-O-beta-D-glucoside form of genistein and is the predominant form of the isoflavone naturally occurring in plants. In fact, studies in the 1970s revealed that 99% of the isoflavonoid compounds in soy are present as their glucosides. The glucosides are converted by digestive enzymes in the digestive system to exert their biological effects. Genistin is also converted to a more familiar genistein, thus, the biological activities including antiatherosclerotic, estrogenic and anticancer effects are analogous. (en) Genistina es una isoflavona encontrada en un número de plantas dietéticas como la soja y el kudzu. Fue aislado por primera vez en 1931 a partir del extracto de metanol 90% de una comida de soja, cuando se encontró que la hidrólisis con ácido clorhídrico produce 1 mol cada uno de genisteína y glucosa. Químicamente es la 7-O-beta-D- glucósido forma de genisteína y es la forma predominante de la isoflavona de origen natural en las plantas. De hecho, estudios realizados en la década de 1970 revelaron que el 99% de los compuestos isoflavonoides de la soja están presentes como sus glucósidos. Los glucósidos son convertidos por las enzimas digestivas en el sistema digestivo para ejercer sus efectos biológicos. Genistina también se convierte en una genisteína más familiar, por lo tanto, las activ (es) |
| rdfs:label | Genistin (en) Genistina (es) |
| owl:differentFrom | dbr:Genistein |
| owl:sameAs | freebase:Genistin yago-res:Genistin wikidata:Genistin http://azb.dbpedia.org/resource/جنیستین dbpedia-es:Genistin dbpedia-fa:Genistin dbpedia-sh:Genistin dbpedia-sr:Genistin https://global.dbpedia.org/id/4kjr3 |
| prov:wasDerivedFrom | wikipedia-en:Genistin?oldid=1059918655&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Genistin.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Genistin |
| foaf:name | Genistin (en) |
| is dbo:wikiPageRedirects of | dbr:Glucosyl-7-genistein dbr:Genistein-7-glucoside dbr:Genistein_7-O-beta-D-glucoside dbr:Genistein_7-glucoside dbr:Genistein_glucoside dbr:Genisteol_7-monoglucoside dbr:Genistine dbr:Genistoside |
| is dbo:wikiPageWikiLink of | dbr:Pueraria_mirifica dbr:Cytisus_scoparius dbr:Genistein dbr:Millettia_nitida dbr:Styphnolobium_japonicum dbr:C21H20O10 dbr:Sarcolobus_globosus dbr:Glucosyl-7-genistein dbr:Genistein-7-glucoside dbr:Genistein_7-O-beta-D-glucoside dbr:Genistein_7-glucoside dbr:Genistein_glucoside dbr:Genisteol_7-monoglucoside dbr:Genistine dbr:Genistoside |
| is owl:differentFrom of | dbr:Genistein |
| is foaf:primaryTopic of | wikipedia-en:Genistin |
