Giant cell (original) (raw)
خلية عملاقة (بالإنجليزية: Giant cell) هي كتلة تتكون من اتحاد عدد من الخلايا البارزة (عادة البلعم). ويمكن أن تنشأ استجابة لعدوى أو جهة خارجية توجد عادة في بعض الالتهابات المزمنة التي تتميز بتكون الورم الحليمي كما في السل الرئوي والساركويد .
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| dbo:abstract | خلية عملاقة (بالإنجليزية: Giant cell) هي كتلة تتكون من اتحاد عدد من الخلايا البارزة (عادة البلعم). ويمكن أن تنشأ استجابة لعدوى أو جهة خارجية توجد عادة في بعض الالتهابات المزمنة التي تتميز بتكون الورم الحليمي كما في السل الرئوي والساركويد . (ar) Una cèl·lula gegant (o cèl·lula gegant multinucleada) és una massa formada per la unió de diverses cèl·lules diferents (normalment histiòcits), sovint formant un granuloma. Pot aparèixer com a resposta a una infecció, com per exemple, de tuberculosi, herpes o VIH, o un cos estrany. Aquestes cèl·lules gegants multinucleades són cèl·lules del llinatge dels monòcits o macròfags fusionats entre si. Els tipus inclouen , , , arteritis de cèl·lules gegants i . (ca) Unter Riesenzelle versteht man in der Histologie eine besonders große Zelle, meist mit mehreren unförmigen oder gelappten Kernen. Riesenzellen entstehen durch Kernteilungen ohne konsekutive Zellteilung oder durch sekundäre Verschmelzung von mehreren Zellen desselben Typus. Abzugrenzen sind sie von morphologischen und funktionellen Syncytien. Einige besonders große, aber einkernige Zellen heißen ebenfalls Riesenzelle, beispielsweise die motorischen Betz-Zellen. Riesenzellen können per Tzanck-Test nachgewiesen werden. Es können drei Typen von Riesenzellen unterschieden werden: 1. * physiologisch vorkommende, beispielsweise Osteoklasten, Langhanszellen (die Langhans-Zellen weisen 2–10 Kerne auf) 2. * durch Zellteilungsstörung entstehende, wie Fremdkörperriesenzellen (100 Kerne), -Riesenzellen 3. * neoplastische, beispielsweise bei Riesenzellleukämie, bei gigantozellulärem Sarkom und gigantozellulärem Karzinom und Sternberg-Reed-Riesenzellen bei Lymphogranulomatose (de) A giant cell (also known as multinucleated giant cell, or multinucleate giant cell) is a mass formed by the union of several distinct cells (usually histiocytes), often forming a granuloma. Although there is typically a focus on the pathological aspects of multinucleate giant cells (MGCs), they also play many important physiological roles. Osteoclasts specifically are invaluable to healthy physiological functions and are key players in the skeletal system. Osteoclasts are frequently classified and discussed separately from other MGCs which are more closely linked with human pathologies. Non-osteoclast MGCs can arise in response to an infection, such as from tuberculosis, herpes, or HIV, or foreign body. These MGCs are cells of monocyte or macrophage lineage fused together. Similar to their monocyte precursors, they are able to phagocytose foreign materials. However, their large size and extensive membrane ruffling make them better equipped to clear up larger particles. They utilize activated CR3s to ingest complement-opsonized targets. Non-osteoclast MGCs are also responsible for the clearance of cell debris which is necessary for tissue remodeling after injuries. Types include foreign-body giant cell, Langhans giant cell, Touton giant cells, Giant-cell arteritis, and Reed–Sternberg cell. (en) Uma célula gigante é uma massa de vários núcleos formada a partir da união de macrófagos, que muitas vezes forma granulomas. Ao redor desta célula existe uma camada de fibroblastos, que com o tempo depositam colágeno, tal que substitui todo o granuloma por uma cicatriz mielinizada. (pt) 巨细胞（英語：giant cell，或称为多核巨细胞）是多个不同细胞（常为）融合在一起形成的，常伴随形成肉芽肿。巨细胞可作为感染的反应而形成，这些感染包括结核病、疱疹或HIV，也可由导致。这些巨细胞（MGCs）是由单核细胞及其巨噬细胞世系融合在一起形成。 巨细胞的种类包括、朗罕氏巨细胞、、及。 (zh) |
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| rdfs:comment | خلية عملاقة (بالإنجليزية: Giant cell) هي كتلة تتكون من اتحاد عدد من الخلايا البارزة (عادة البلعم). ويمكن أن تنشأ استجابة لعدوى أو جهة خارجية توجد عادة في بعض الالتهابات المزمنة التي تتميز بتكون الورم الحليمي كما في السل الرئوي والساركويد . (ar) Una cèl·lula gegant (o cèl·lula gegant multinucleada) és una massa formada per la unió de diverses cèl·lules diferents (normalment histiòcits), sovint formant un granuloma. Pot aparèixer com a resposta a una infecció, com per exemple, de tuberculosi, herpes o VIH, o un cos estrany. Aquestes cèl·lules gegants multinucleades són cèl·lules del llinatge dels monòcits o macròfags fusionats entre si. Els tipus inclouen , , , arteritis de cèl·lules gegants i . (ca) Uma célula gigante é uma massa de vários núcleos formada a partir da união de macrófagos, que muitas vezes forma granulomas. Ao redor desta célula existe uma camada de fibroblastos, que com o tempo depositam colágeno, tal que substitui todo o granuloma por uma cicatriz mielinizada. (pt) 巨细胞（英語：giant cell，或称为多核巨细胞）是多个不同细胞（常为）融合在一起形成的，常伴随形成肉芽肿。巨细胞可作为感染的反应而形成，这些感染包括结核病、疱疹或HIV，也可由导致。这些巨细胞（MGCs）是由单核细胞及其巨噬细胞世系融合在一起形成。 巨细胞的种类包括、朗罕氏巨细胞、、及。 (zh) Unter Riesenzelle versteht man in der Histologie eine besonders große Zelle, meist mit mehreren unförmigen oder gelappten Kernen. Riesenzellen entstehen durch Kernteilungen ohne konsekutive Zellteilung oder durch sekundäre Verschmelzung von mehreren Zellen desselben Typus. Abzugrenzen sind sie von morphologischen und funktionellen Syncytien. Einige besonders große, aber einkernige Zellen heißen ebenfalls Riesenzelle, beispielsweise die motorischen Betz-Zellen. Riesenzellen können per Tzanck-Test nachgewiesen werden. Es können drei Typen von Riesenzellen unterschieden werden: (de) A giant cell (also known as multinucleated giant cell, or multinucleate giant cell) is a mass formed by the union of several distinct cells (usually histiocytes), often forming a granuloma. Although there is typically a focus on the pathological aspects of multinucleate giant cells (MGCs), they also play many important physiological roles. Osteoclasts specifically are invaluable to healthy physiological functions and are key players in the skeletal system. Osteoclasts are frequently classified and discussed separately from other MGCs which are more closely linked with human pathologies. (en) |
| rdfs:label | خلية عملاقة (ar) Cèl·lula gegant (ca) Riesenzelle (de) Giant cell (en) Célula gigante (pt) 巨细胞 (zh) |
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