Hensen's cell (original) (raw)
Hensen's cells are a layer of tall cells arranged in the organ of Corti in the cochlea, which are part of the supporting cells lie on the outer hair cells (OHC). Their appearance are upper part wide with lower part narrow, column like cells. One significant morphologic feature of Hensen's cells is the lipid droplets, which are most noticeable at the third and forth turns of the cochlear, the lipid droplets are thought to have association with the auditory process because they are parallel to the innervation. One significant structure found among the Hensen's cells and the hair cells are the gap junctions, they are made of connexins which serve important function in distribution and connection between cells, the gaps enable the long distance of electric communication.
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| dbo:abstract | Hensen's cells are a layer of tall cells arranged in the organ of Corti in the cochlea, which are part of the supporting cells lie on the outer hair cells (OHC). Their appearance are upper part wide with lower part narrow, column like cells. One significant morphologic feature of Hensen's cells is the lipid droplets, which are most noticeable at the third and forth turns of the cochlear, the lipid droplets are thought to have association with the auditory process because they are parallel to the innervation. One significant structure found among the Hensen's cells and the hair cells are the gap junctions, they are made of connexins which serve important function in distribution and connection between cells, the gaps enable the long distance of electric communication. There are increased evidence which show that Hensen's cells are critical in many functions, they act as mediators of ion metabolism, the K+ spatial buffering pathway, the neuron innervation, and the purinergic receptors that found in the Hensen's cells are all important in providing a suitable electrical and micro mechanical environment to support hair cells and to maintain homeostasis of the Organ of Corti. Furthermore, Hensen's cells are also able to regenerate the damaged hair cells in the vertebrates, they undergo phagocytosis to eject the dead or injured hair cells, and reproduce both new hair cells and supporting cells into the cell cycle, one of the reasons is because the supporting cells are differentiated by the embryonic hair cells, but why the regeneration function is not found in the mammals cells are remain unclear. In addition to the regeneration of new hair cells, Hensen's cells are currently being investigated to be promising targets for gene therapy and regenerative medicine. Hensen's cells are named after German anatomist and physiologist, Victor Hensen (1835-1924). (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Organ_of_corti.svg?width=300 |
| dbo:wikiPageID | 60786107 (xsd:integer) |
| dbo:wikiPageLength | 20127 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1099277591 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Cadherin dbr:Endolymph dbr:Endoplasmic_reticulum dbr:Pathophysiology dbr:Homeostasis dbr:Vertebrate dbr:Depolarization dbr:Phagocytosis dbr:Victor_Hensen dbr:Notch_signaling_pathway dbr:Cochlea dbr:Gentamicin dbr:Mitochondrion dbr:Connexin dbr:Physiological dbr:Apoptosis dbr:Lucifer_yellow dbr:Trifluoperazine dbr:Purinergic_receptor dbr:6-Carboxyfluorescein dbr:Fluorescein dbr:Nonsyndromic_deafness dbr:Golgi_apparatus dbr:Organ_of_Corti dbc:Auditory_system dbr:Metabolism dbr:Radical_(chemistry) dbr:Laser_scanning_confocal_microscopy dbr:Perilymph dbr:Phagosome dbr:Glial_Cells |
| dbp:caption | Schematic anatomy of the Organ of Corti, the Hensen's cells form part of the outer hair cells. (en) |
| dbp:name | Hensen's cells (en) |
| dbp:system | Supporting system (en) |
| dbp:wikiPageUsesTemplate | dbt:Infobox_anatomy dbt:Further dbt:Reflist dbt:Auditory_and_vestibular_anatomy |
| dcterms:subject | dbc:Auditory_system |
| rdf:type | owl:Thing wikidata:Q4936952 dbo:AnatomicalStructure |
| rdfs:comment | Hensen's cells are a layer of tall cells arranged in the organ of Corti in the cochlea, which are part of the supporting cells lie on the outer hair cells (OHC). Their appearance are upper part wide with lower part narrow, column like cells. One significant morphologic feature of Hensen's cells is the lipid droplets, which are most noticeable at the third and forth turns of the cochlear, the lipid droplets are thought to have association with the auditory process because they are parallel to the innervation. One significant structure found among the Hensen's cells and the hair cells are the gap junctions, they are made of connexins which serve important function in distribution and connection between cells, the gaps enable the long distance of electric communication. (en) |
| rdfs:label | Hensen's cell (en) |
| owl:sameAs | wikidata:Hensen's cell https://global.dbpedia.org/id/9jd6n |
| prov:wasDerivedFrom | wikipedia-en:Hensen's_cell?oldid=1099277591&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Organ_of_corti.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Hensen's_cell |
| foaf:name | Hensen's cells (en) |
| is dbo:wikiPageRedirects of | dbr:Hensen's_cells dbr:Hensen_cell |
| is dbo:wikiPageWikiLink of | dbr:List_of_distinct_cell_types_in_the_adult_human_body dbr:Malvin_Carl_Teich dbr:Hensen's_cells dbr:Hensen_cell |
| is foaf:primaryTopic of | wikipedia-en:Hensen's_cell |
