| dbo:abstract |
الهيكسون (بالإنجليزية: Hexon protein) في البيولوجيا الجزيئية بروتين الهيكسون هو المعطف البروتيني الرئيسي الموجود لدى الفيروسات الغدانية. معطف هيكسون البروتيني يتم تجميعه خلال أواخر العدوى. يتم تنظيم النسخ الـ 240 من مثلوث الهيكسون التي تم إنتاجها حتى تقع 12 على كل جانب من الجوانب العشرين. (ar) In molecular biology, the hexon protein is a major coat protein found in Adenoviruses. Hexon coat proteins are synthesised during late infection and form homo-trimers. The 240 copies of the hexon trimer that are produced are organised so that 12 lie on each of the 20 facets. The central 9 hexons in a facet are cemented together by 12 copies of polypeptide IX. The penton complex, formed by the peripentonal hexons and penton base (holding in place a fibre), lie at each of the 12 vertices. The hexon coat protein is a duplication consisting of two domains with a similar fold packed together like the nucleoplasmin subunits. Within a hexon trimer, the domains are arranged around a pseudo 6-fold axis. The domains have a beta-sandwich structure consisting of 8 strands in two sheets with a jelly-roll topology; each domain is heavily decorated with many insertions. Some hexon proteins contain a distinct C-terminal domain. Hexon directly recruits the cellular motor protein dynein in a pH-dependent manner. The dynein-regulatory protein, dynactin, was found to play a clear role in regulating the dynein-adenovirus complex transport to the nucleus. (en) |
| dbo:symbol |
Adeno_hexon Adeno_hexon_C |
| dbo:thumbnail |
wiki-commons:Special:FilePath/PDB_1p2z_EBI.jpg?width=300 |
| dbo:wikiPageID |
32019969 (xsd:integer) |
| dbo:wikiPageLength |
3428 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
966140723 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Beta_sheet dbr:Dynactin dbr:Dynein dbr:Neuron dbr:Protein_subunit dbr:Protein_domain dbr:Protein_folding dbr:Protein dbc:Protein_domains dbr:Axon dbr:Infection dbr:Exon dbr:Secondary_structure dbr:Polypeptide dbr:Adenoviruses dbr:Trimer_(biochemistry) |
| dbp:caption |
the quasi-atomic model of human adenovirus type 5 capsid (en) refinement of adenovirus type 2 hexon with cns (en) |
| dbp:interpro |
IPR016107 (en) IPR016108 (en) |
| dbp:name |
Adeno_hexon (en) Adeno_hexon_C (en) |
| dbp:pfam |
PF01065 (en) PF03678 (en) |
| dbp:scop |
1 (xsd:integer) |
| dbp:symbol |
Adeno_hexon (en) Adeno_hexon_C (en) |
| dbp:wikiPageUsesTemplate |
dbt:Distinguish dbt:Infobox_protein_family dbt:InterPro_content dbt:Reflist |
| dcterms:subject |
dbc:Protein_domains |
| gold:hypernym |
dbr:Protein |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:Abstraction100002137 yago:Family108078020 yago:Group100031264 yago:Organization108008335 yago:YagoLegalActor yago:YagoLegalActorGeo yago:YagoPermanentlyLocatedEntity dbo:Protein yago:SocialGroup107950920 yago:Unit108189659 |
| rdfs:comment |
الهيكسون (بالإنجليزية: Hexon protein) في البيولوجيا الجزيئية بروتين الهيكسون هو المعطف البروتيني الرئيسي الموجود لدى الفيروسات الغدانية. معطف هيكسون البروتيني يتم تجميعه خلال أواخر العدوى. يتم تنظيم النسخ الـ 240 من مثلوث الهيكسون التي تم إنتاجها حتى تقع 12 على كل جانب من الجوانب العشرين. (ar) In molecular biology, the hexon protein is a major coat protein found in Adenoviruses. Hexon coat proteins are synthesised during late infection and form homo-trimers. The 240 copies of the hexon trimer that are produced are organised so that 12 lie on each of the 20 facets. The central 9 hexons in a facet are cemented together by 12 copies of polypeptide IX. The penton complex, formed by the peripentonal hexons and penton base (holding in place a fibre), lie at each of the 12 vertices. The hexon coat protein is a duplication consisting of two domains with a similar fold packed together like the nucleoplasmin subunits. Within a hexon trimer, the domains are arranged around a pseudo 6-fold axis. The domains have a beta-sandwich structure consisting of 8 strands in two sheets with a jelly-ro (en) |
| rdfs:label |
هيكسون (ar) Hexon protein (en) |
| owl:sameAs |
freebase:Hexon protein wikidata:Hexon protein dbpedia-ar:Hexon protein https://global.dbpedia.org/id/44hLG |
| prov:wasDerivedFrom |
wikipedia-en:Hexon_protein?oldid=966140723&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/PDB_1p2z_EBI.jpg wiki-commons:Special:FilePath/PDB_2bvi_EBI.jpg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Hexon_protein |
| is dbo:wikiPageWikiLink of |
dbr:VA_RNA dbr:R-loop dbr:Sputnik_virophage dbr:Mastadenovirus dbr:Adenoviridae dbr:Adenovirus_genome dbr:Capsomere dbr:B_virus dbr:Human_herpesvirus_6 dbr:Virus dbr:Exon |
| is foaf:primaryTopic of |
wikipedia-en:Hexon_protein |
