dbo:abstract |
La metilmalonil-CoA descarboxilasa (EC 4.1.1.41) es una enzima que cataliza la descarboxilación del metilmalonato a propanoato y dióxido de carbono. Requiere como cofactor biotina. S-metilmalonil-CoA Propanoil-CoA + CO2 La enzima de la es una biotinil-proteína que requiere sodio y actúa como una bomba de sodio. La enzima de la Escherichia coli se presenta como dímero de homotrímeros. (es) In enzymology, a methylmalonyl-CoA decarboxylase (EC 7.2.4.3) is an enzyme that catalyzes the chemical reaction (S)-methylmalonyl-CoA propanoyl-CoA + CO2 Hence, this enzyme has one substrate, , and two products, propanoyl-CoA and CO2. Along with this reaction, this enzyme transports sodium cations across the membrane, creating a gradient which can be used for synthesis of ATP, hence its classification as a translocase. This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming). Other names in common use include propionyl-CoA carboxylase, propionyl coenzyme A carboxylase, methylmalonyl-coenzyme A decarboxylase, (S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase [incorrect], and (S)-methylmalonyl-CoA carboxy-lyase. This enzyme participates in propanoate metabolism. (en) |
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7.2.4.3 |
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Methylmalonyl CoA decarboxylase trimer, E.Coli (en) |
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methylmalonyl-CoA decarboxylase (en) |
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La metilmalonil-CoA descarboxilasa (EC 4.1.1.41) es una enzima que cataliza la descarboxilación del metilmalonato a propanoato y dióxido de carbono. Requiere como cofactor biotina. S-metilmalonil-CoA Propanoil-CoA + CO2 La enzima de la es una biotinil-proteína que requiere sodio y actúa como una bomba de sodio. La enzima de la Escherichia coli se presenta como dímero de homotrímeros. (es) In enzymology, a methylmalonyl-CoA decarboxylase (EC 7.2.4.3) is an enzyme that catalyzes the chemical reaction (S)-methylmalonyl-CoA propanoyl-CoA + CO2 Hence, this enzyme has one substrate, , and two products, propanoyl-CoA and CO2. Along with this reaction, this enzyme transports sodium cations across the membrane, creating a gradient which can be used for synthesis of ATP, hence its classification as a translocase. (en) |
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Metilmalonil-CoA descarboxilasa (es) Methylmalonyl-CoA decarboxylase (en) |
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