Motility protein A (original) (raw)
MotA é uma proteína. É um componente do motor flagelar. Mais especificamente, MotA e formam o estator do flagelo e rodeiam o rotor, como um anel de 8-10 partículas. MotA e MotB são proteínas integrais de membrana. MotA possui quatro domínios transmembranares. Ambas as proteínas fazem parte de canal de H+ que torna possível o fluxo de protões e a rotação do motor. Em mutantes motA, a função do motor é restabelecida se a proteína MotA for expressa.
| Property | Value |
|---|---|
| dbo:abstract | Motility protein A, MotA, is a bacterial protein that is encoded by the motA gene. It is a component of the flagellar motor. More specifically, MotA and MotB make the stator of a H+ driven bacterial flagella and surround the rotor as a ring of about 8–10 particles. MotA and MotB are integral membrane proteins. MotA has four transmembrane domains. Both proteins are part of the H+ channel that makes possible the flux of protons and the motor's rotation. In MotA mutants, the motor function is re-established if the MotA protein is expressed. Though MotA and MotB are part of the proteins required for H+ mediated flagellar motility, they show a high degree of homology to the PomA and PomB proteins present in bacterial species utilizing Na+ ion fluxes to power flagella and studies have revealed that a 'pomA' mutant of Vibrio alginolyticus can regain motility by expression of MotA. As restoring motility of pomA mutants by heterologous expression of MotA does not change the ion used to power the flagellum of the transgenic Vibrio alginolyticus, MotA is not in itself an essential specificity factor in ion selectivity, though that does not exclude it being partially involved in determining ion specificity of the flagellar complex. (en) MotA é uma proteína. É um componente do motor flagelar. Mais especificamente, MotA e formam o estator do flagelo e rodeiam o rotor, como um anel de 8-10 partículas. MotA e MotB são proteínas integrais de membrana. MotA possui quatro domínios transmembranares. Ambas as proteínas fazem parte de canal de H+ que torna possível o fluxo de protões e a rotação do motor. Em mutantes motA, a função do motor é restabelecida se a proteína MotA for expressa. (pt) |
| dbo:wikiPageExternalLink | https://archive.org/details/The_Prokaryotes_Vol._1_Symbiotic_Associations_Biotechnology_Applied_Microbiology |
| dbo:wikiPageID | 23518576 (xsd:integer) |
| dbo:wikiPageLength | 4044 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1117667580 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Proton dbr:Rotating_locomotion_in_living_systems dbr:Archaellum dbr:Integral_membrane_protein dbr:Undulipodium dbr:Gene dbr:MotB dbr:Vibrio_alginolyticus dbr:Stator dbr:PomA dbc:Bacterial_proteins dbr:Ciliopathy dbr:Cilium dbr:Protein dbr:Heterologous_expression dbc:Motor_proteins dbr:Flagellum dbr:PomB |
| dbp:altsymbols | ECK1891; flaJ; JW1879 (en) |
| dbp:chromosome | chromosome (en) |
| dbp:entrezchromosome | NC_000913 (en) |
| dbp:entrezgene | 947564 (xsd:integer) |
| dbp:genlocEnd | 1975295 (xsd:integer) |
| dbp:genlocStart | 1974142 (xsd:integer) |
| dbp:name | Motility protein A (en) |
| dbp:organism | Escherichia coli str. K-12 (en) |
| dbp:refseqprotein | NP_416404.1 (en) |
| dbp:symbol | motA (en) |
| dbp:taxid | 511145 (xsd:integer) |
| dbp:uniprot | P09348 (en) |
| dbp:wikiPageUsesTemplate | dbt:Cite_book dbt:Clear dbt:Infobox_nonhuman_protein dbt:Protein-stub dbt:Refbegin dbt:Refend dbt:Reflist dbt:Use_dmy_dates |
| dct:subject | dbc:Bacterial_proteins dbc:Motor_proteins |
| rdfs:comment | MotA é uma proteína. É um componente do motor flagelar. Mais especificamente, MotA e formam o estator do flagelo e rodeiam o rotor, como um anel de 8-10 partículas. MotA e MotB são proteínas integrais de membrana. MotA possui quatro domínios transmembranares. Ambas as proteínas fazem parte de canal de H+ que torna possível o fluxo de protões e a rotação do motor. Em mutantes motA, a função do motor é restabelecida se a proteína MotA for expressa. (pt) Motility protein A, MotA, is a bacterial protein that is encoded by the motA gene. It is a component of the flagellar motor. More specifically, MotA and MotB make the stator of a H+ driven bacterial flagella and surround the rotor as a ring of about 8–10 particles. MotA and MotB are integral membrane proteins. MotA has four transmembrane domains. Both proteins are part of the H+ channel that makes possible the flux of protons and the motor's rotation. In MotA mutants, the motor function is re-established if the MotA protein is expressed. (en) |
| rdfs:label | Motility protein A (en) MotA (pt) |
| owl:sameAs | wikidata:Motility protein A dbpedia-pt:Motility protein A https://global.dbpedia.org/id/2Kr5F |
| prov:wasDerivedFrom | wikipedia-en:Motility_protein_A?oldid=1117667580&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Motility_protein_A |
| is dbo:wikiPageRedirects of | dbr:MotA |
| is dbo:wikiPageWikiLink of | dbr:MotA |
| is foaf:primaryTopic of | wikipedia-en:Motility_protein_A |