| dbo:abstract |
N-acetilltransferasa, en anglès:N-acetyltransferase, és un enzim que catalitza la transferència de grups acetil des del acetyl-CoA a arilamines. Tenen una alta especificitat per les amines aromàtiques, particularment la serotonina i també poden catalitzar transferència d'acetil entre arilamines sense CoA. EC 2.3.1.5. (ca) N-أسيتيل ترانسفيريز (بالإنجليزية: N-acetyltransferase) هو إنزيم يحفز انتقال مجموعة الأسيتيل من الأسيتيل مرافق الإنزيم-أ إلى الأريلأمينات. (ar) N-acetyltransferase (NAT) is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines, arylhydroxylamines and arylhydrazines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. N-acetyltransferases are cytosolic enzymes found in the liver and many tissues of most mammalian species, except the dog and fox, which cannot acetylate xenobiotics.Acetyl groups are important in the conjugation of metabolites from the liver, to allow excretion of the byproducts (phase II metabolism). This is especially important in the metabolism and excretion of drug products (drug metabolism). (en) N-乙酰基转移酶（英語：N-acetyltransferase）是一类能催化乙酰基团在乙酰辅酶A和胺之间转移的酶。这些酶对芳香胺有着广泛的选择特异性，特别是对丝氨酸，甚至能在两个芳香胺之间转移乙酰基而不经过CoA。 (zh) |
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2.3.1.5 |
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Arylamine N-acetyltransferase 2 (en) |
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dbc:EC_2.3.1 |
| gold:hypernym |
dbr:Enzyme |
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| rdfs:comment |
N-acetilltransferasa, en anglès:N-acetyltransferase, és un enzim que catalitza la transferència de grups acetil des del acetyl-CoA a arilamines. Tenen una alta especificitat per les amines aromàtiques, particularment la serotonina i també poden catalitzar transferència d'acetil entre arilamines sense CoA. EC 2.3.1.5. (ca) N-أسيتيل ترانسفيريز (بالإنجليزية: N-acetyltransferase) هو إنزيم يحفز انتقال مجموعة الأسيتيل من الأسيتيل مرافق الإنزيم-أ إلى الأريلأمينات. (ar) N-acetyltransferase (NAT) is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines, arylhydroxylamines and arylhydrazines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. N-acetyltransferases are cytosolic enzymes found in the liver and many tissues of most mammalian species, except the dog and fox, which cannot acetylate xenobiotics.Acetyl groups are important in the conjugation of metabolites from the liver, to allow excretion of the byproducts (phase II metabolism). This is especially important in the metabolism and excretion of drug products (drug metabolism). (en) N-乙酰基转移酶（英語：N-acetyltransferase）是一类能催化乙酰基团在乙酰辅酶A和胺之间转移的酶。这些酶对芳香胺有着广泛的选择特异性，特别是对丝氨酸，甚至能在两个芳香胺之间转移乙酰基而不经过CoA。 (zh) |
| rdfs:label |
N-أسيتيل ترانسفيريز (ar) N-acetiltransferasa (ca) N-acetyltransferase (en) N-乙酰基转移酶 (zh) |
| owl:sameAs |
freebase:N-acetyltransferase yago-res:N-acetyltransferase wikidata:N-acetyltransferase dbpedia-ar:N-acetyltransferase dbpedia-ca:N-acetyltransferase dbpedia-zh:N-acetyltransferase https://global.dbpedia.org/id/4s41P |
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Arylamine N-acetyltransferase 2 (en) |
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