Octreotide scan (original) (raw)

dbo:abstract

Die Somatostatin-Rezeptor-Szintigrafie, englisch auch Octreotid-Scan genannt, ist ein bildgebendes Verfahren, das im Wesentlichen in der Diagnostik von neuroendokrinen Tumoren (NET) verwendet wird. (de)
An octreotide scan is a type of SPECT scintigraphy used to find carcinoid, pancreatic neuroendocrine tumors, and to localize sarcoidosis. It is also called somatostatin receptor scintigraphy (SRS). Octreotide, a drug similar to somatostatin, is radiolabeled with indium-111, and is injected into a vein and travels through the bloodstream. The radioactive octreotide attaches to tumor cells that have receptors for somatostatin (i.e. gastrinoma, glucagonoma, etc.). A gamma camera detects the radioactive octreotide, and makes pictures showing where the tumor cells are in the body, typically by a SPECT technique. A technetium-99m based radiopharmaceutical kit is also available. Octreotide scanning is reported to have a sensitivity between 75% and 100% for detecting pancreatic neuroendocrine tumors. Instead of gamma-emitting 111In, certain octreotide derivatives such as edotreotide (DOTATOC) or DOTATATE are able to be linked by chelation to positron-emitting isotopes such as gallium-68 and copper-64 which in turn can be evaluated with more precise (compared with SPECT) scanning techniques such as PET-CT. Thus, the octreotide scan is now being replaced in most centers with gallium-68 DOTATATE and copper-64 DOTATATE scans. Somatostatin receptor imaging can now be performed with positron emission tomography (PET) which offers higher resolution and more rapid imaging. (en)
Scyntygrafia receptorowa – badanie scyntygraficzne pozwalające ocenić obecność i rozmieszczenie receptorów somatostatynowych w tkankach. Duża gęstość receptorów wskazuje na patologiczny charakter tkanki, np. guzów neuroendokrynnych przewodu pokarmowego (GEP NET), gruczolaków przysadki, ziarniniaków i ognisk aktywacji leukocytów w przebiegu chorób z autoimmunizacji. Metoda polega na podaniu dożylnym analogów somatostatyny (najczęściej oktreotydu) skoniugowanych z niewielkimi cząsteczkami związków organicznych (np. DTPA) i jonami izotopów promieniotwórczych (indu 111, technetu 99m). (pl)

dbo:alternativeName

Octreoscan (en)

dbo:casNumber

139096-04-1

dbo:drugbank

DB11835

dbo:fdaUniiCode

M312JJ6Z32

dbo:pubchem

131704321

dbo:thumbnail

wiki-commons:Special:FilePath/Octreoscan.jpg?width=300

dbo:wikiPageExternalLink

dbo:wikiPageID

16081263 (xsd:integer)

dbo:wikiPageLength

13076 (xsd:nonNegativeInteger)

dbo:wikiPageRevisionID

1110801504 (xsd:integer)

dbo:wikiPageWikiLink

dbp:atcPrefix

V09 (en)

dbp:atcSuffix

IB01 (en)

dbp:caption

111 (xsd:integer)

dbp:casNumber

139096 (xsd:integer)

dbp:dailymedid

Indium_in-111_pentetreotide (en)

dbp:drugName

Indium In-111 pentetreotide (en)

dbp:drugbank

DB11835 (en)

dbp:legalUs

Rx-only (en)

dbp:name

Octreotide scan (en)

dbp:pubchem

131704321 (xsd:integer)

dbp:routesOfAdministration

dbr:Intravenous

dbp:smiles

[111In+3].CCCN=CC1CSSCCC=NCC=NCC=NCC=NCC=N1 (en)

dbp:stdinchi

1 (xsd:integer)

dbp:stdinchikey

ZKZPXKKVDJOAIS-JWFOFJTQSA-J (en)

dbp:synonyms

MP-1727 (en)
ocreoscan (en)

dbp:tradename

Octreoscan (en)

dbp:unii

M312JJ6Z32 (en)

dbp:width

250 (xsd:integer)

dbp:wikiPageUsesTemplate

dcterms:subject

gold:hypernym

dbr:Scintigraphy

rdf:type

rdfs:comment

Die Somatostatin-Rezeptor-Szintigrafie, englisch auch Octreotid-Scan genannt, ist ein bildgebendes Verfahren, das im Wesentlichen in der Diagnostik von neuroendokrinen Tumoren (NET) verwendet wird. (de)
Scyntygrafia receptorowa – badanie scyntygraficzne pozwalające ocenić obecność i rozmieszczenie receptorów somatostatynowych w tkankach. Duża gęstość receptorów wskazuje na patologiczny charakter tkanki, np. guzów neuroendokrynnych przewodu pokarmowego (GEP NET), gruczolaków przysadki, ziarniniaków i ognisk aktywacji leukocytów w przebiegu chorób z autoimmunizacji. Metoda polega na podaniu dożylnym analogów somatostatyny (najczęściej oktreotydu) skoniugowanych z niewielkimi cząsteczkami związków organicznych (np. DTPA) i jonami izotopów promieniotwórczych (indu 111, technetu 99m). (pl)
An octreotide scan is a type of SPECT scintigraphy used to find carcinoid, pancreatic neuroendocrine tumors, and to localize sarcoidosis. It is also called somatostatin receptor scintigraphy (SRS). Octreotide, a drug similar to somatostatin, is radiolabeled with indium-111, and is injected into a vein and travels through the bloodstream. The radioactive octreotide attaches to tumor cells that have receptors for somatostatin (i.e. gastrinoma, glucagonoma, etc.). A gamma camera detects the radioactive octreotide, and makes pictures showing where the tumor cells are in the body, typically by a SPECT technique. A technetium-99m based radiopharmaceutical kit is also available. (en)

rdfs:label

Somatostatin-Rezeptor-Szintigrafie (de)
Octreoscan (it)
Octreotide scan (en)
Scyntygrafia receptorowa (pl)

owl:sameAs

prov:wasDerivedFrom

wikipedia-en:Octreotide_scan?oldid=1110801504&ns=0

foaf:depiction

foaf:isPrimaryTopicOf

wikipedia-en:Octreotide_scan

foaf:name

Indium In-111 pentetreotide (en)

is dbo:wikiPageRedirects of

is dbo:wikiPageWikiLink of

is foaf:primaryTopic of

wikipedia-en:Octreotide_scan