Ribonuclease T (original) (raw)
Ribonuclease T (RNase T, exonuclease T, exo T) is a ribonuclease enzyme involved in the maturation of transfer RNA and ribosomal RNA in bacteria, as well as in DNA repair pathways. It is a member of the DnaQ family of exonucleases and non-processively acts on the 3' end of single-stranded nucleic acids. RNase T is capable of cleaving both DNA and RNA, with extreme sequence specificity discriminating against cytosine at the 3' end of the substrate.
| Property | Value |
|---|---|
| dbo:abstract | Ribonuclease T (RNase T, exonuclease T, exo T) is a ribonuclease enzyme involved in the maturation of transfer RNA and ribosomal RNA in bacteria, as well as in DNA repair pathways. It is a member of the DnaQ family of exonucleases and non-processively acts on the 3' end of single-stranded nucleic acids. RNase T is capable of cleaving both DNA and RNA, with extreme sequence specificity discriminating against cytosine at the 3' end of the substrate. (en) Рибонуклеаза T (РНКаза T, экзонуклеаза T, exo T) — фермент рибонуклеаза, действующая при созревании транспортных и рибосомных РНК у бактерий, а также в процессах репарации ДНК. Рибонуклеаза T входит в семейство экзонуклеаз . Она действует на 3'-конец одноцепочечных нуклеиновых кислот и может расщеплять как ДНК, так и РНК с высокой специфичностью дискриминируя остаток цитозин на 3'-конце субстрата. (ru) |
| dbo:symbol | rnt |
| dbo:thumbnail | wiki-commons:Special:FilePath/rnaseT.png?width=300 |
| dbo:wikiPageID | 45256144 (xsd:integer) |
| dbo:wikiPageLength | 9941 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1044706714 (xsd:integer) |
| dbo:wikiPageWikiLink | dbc:Ribonucleases dbr:Processivity dbr:Ribonuclease dbr:DNA dbr:DNA_polymerase_III_holoenzyme dbr:DNA_repair dbr:UV dbr:Nucleic_acid dbr:Transfer_RNA dbr:Enzyme dbr:Gammaproteobacteria dbr:Glutamic_acid dbr:Substrate_(chemistry) dbr:Bacteria dbr:DnaQ dbr:23S_ribosomal_RNA dbr:Adenosine_monophosphate dbc:EC_3.1.13 dbr:Cytosine dbr:E._coli dbr:RNA dbr:Aromatic dbr:Phenylalanine dbr:DNA_sequence dbr:Exonuclease dbr:Ribosomal_RNA dbr:Pi_orbital dbr:5S_rRNA dbr:3' dbr:Single-stranded dbr:File:RNAse_T_pi_interactions.png |
| dbp:caption | A ribonuclease T dimer in complex with DNA , from PDB ID 3NH1. (en) |
| dbp:interpro | IPR013520 (en) |
| dbp:name | Ribonuclease T (en) |
| dbp:pfam | PF00929 (en) |
| dbp:smart | SM00479 (en) |
| dbp:symbol | rnt (en) |
| dbp:wikiPageUsesTemplate | dbt:Distinguish dbt:Enzymes dbt:Esterases dbt:Infobox_protein_family dbt:Portal_bar dbt:Reflist |
| dcterms:subject | dbc:Ribonucleases dbc:EC_3.1.13 |
| gold:hypernym | dbr:Enzyme |
| rdf:type | owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 dbo:Protein |
| rdfs:comment | Ribonuclease T (RNase T, exonuclease T, exo T) is a ribonuclease enzyme involved in the maturation of transfer RNA and ribosomal RNA in bacteria, as well as in DNA repair pathways. It is a member of the DnaQ family of exonucleases and non-processively acts on the 3' end of single-stranded nucleic acids. RNase T is capable of cleaving both DNA and RNA, with extreme sequence specificity discriminating against cytosine at the 3' end of the substrate. (en) Рибонуклеаза T (РНКаза T, экзонуклеаза T, exo T) — фермент рибонуклеаза, действующая при созревании транспортных и рибосомных РНК у бактерий, а также в процессах репарации ДНК. Рибонуклеаза T входит в семейство экзонуклеаз . Она действует на 3'-конец одноцепочечных нуклеиновых кислот и может расщеплять как ДНК, так и РНК с высокой специфичностью дискриминируя остаток цитозин на 3'-конце субстрата. (ru) |
| rdfs:label | Ribonuclease T (en) Рибонуклеаза T (ru) |
| owl:differentFrom | dbr:Ribonuclease_T2 dbr:Ribonuclease_T1 |
| owl:sameAs | freebase:Ribonuclease T wikidata:Ribonuclease T dbpedia-ru:Ribonuclease T https://global.dbpedia.org/id/pHCx |
| prov:wasDerivedFrom | wikipedia-en:Ribonuclease_T?oldid=1044706714&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/RNAse_T_pi_interactions.png wiki-commons:Special:FilePath/rnaseT.png |
| foaf:isPrimaryTopicOf | wikipedia-en:Ribonuclease_T |
| is dbo:wikiPageRedirects of | dbr:RNase_T dbr:Exo_T dbr:Exonuclease_T |
| is dbo:wikiPageWikiLink of | dbr:RNase_T dbr:Exo_T dbr:Exonuclease_T |
| is owl:differentFrom of | dbr:Ribonuclease_T2 dbr:Ribonuclease_T1 |
| is foaf:primaryTopic of | wikipedia-en:Ribonuclease_T |
