Relaxin family peptide hormones (original) (raw)
Relaxin family peptide hormones in humans are represented by seven members: three relaxin-like (RLN) and four insulin-like (INSL) peptides: RLN1, RLN2, RNL3, INSL3, INSL4, INSL5, INSL6. This subdivision into two classes (RLN and INSL) is based primarily on early findings, and does not reflect the evolutionary origins or physiological differences between peptides. For example, it is known that the genes coding for RLN3 and INSL5 arose from one ancestral gene, and INSL3 shares origin with RLN2 and its multiple duplicates: RLN1, INSL4, INSL6.
| Property | Value |
|---|---|
| dbo:abstract | Relaxin family peptide hormones in humans are represented by seven members: three relaxin-like (RLN) and four insulin-like (INSL) peptides: RLN1, RLN2, RNL3, INSL3, INSL4, INSL5, INSL6. This subdivision into two classes (RLN and INSL) is based primarily on early findings, and does not reflect the evolutionary origins or physiological differences between peptides. For example, it is known that the genes coding for RLN3 and INSL5 arose from one ancestral gene, and INSL3 shares origin with RLN2 and its multiple duplicates: RLN1, INSL4, INSL6. (en) |
| dbo:arm | p q |
| dbo:band | 13.3 ter |
| dbo:chromosome | 1 19 9 |
| dbo:entrezgene | 6019 6013 117579 |
| dbo:hgncid | 10026 10027 17135 |
| dbo:locusSupplementaryData | -q12 |
| dbo:omim | 179730 (xsd:integer) 179740 (xsd:integer) 606855 (xsd:integer) |
| dbo:pdb | 6RLX |
| dbo:refseq | NM_006911 NM_080864 NM_134441 |
| dbo:symbol | H1 H2, RLXH2, bA12D24.1.1, bA12D24.1.2 INSL3 INSL5 RLN1 RLN2 RLN3 ZINS4, RXN3, H3 |
| dbo:thumbnail | wiki-commons:Special:FilePath/relaxin.png?width=300 |
| dbo:uniprot | P04090 P04808 Q8WXF3 |
| dbo:wikiPageID | 37313606 (xsd:integer) |
| dbo:wikiPageLength | 14110 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1113655288 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Patiria_pectinifera dbr:Mouse_models_of_human_disease dbr:Appetite dbr:Cytoplasm dbr:Carboxyl-terminal dbr:Pubic_symphysis dbr:G_protein-coupled_receptors dbr:Nucleoplasm dbr:Nucleus_incertus dbr:Preprohormone dbc:Hormones_of_the_pregnant_female dbr:Childbirth dbr:Chromosome_19 dbr:Stress_(biology) dbc:Hormones_of_the_ovary dbc:Human_female_endocrine_system dbr:G_protein dbr:Relaxin-3 dbr:Amphioxus dbr:Follicle-stimulating_hormone dbr:Cell_membrane dbr:Central_nervous_system dbr:Chromosome_1 dbr:Chromosome_9 dbr:Hindbrain dbr:Tetrapod dbr:Hypothalamic–pituitary–gonadal_axis dbr:INSL5 dbc:Peptide_hormones dbr:Tertiary_structure dbr:INSL3 dbr:INSL4 dbr:Relaxin dbr:Disulfide_bonds dbr:Teleost_fish dbr:INSL6 dbr:Somatostatin dbr:Relaxin/insulin-like_family_peptide_receptor_1 dbc:Hormones_of_the_placenta dbr:Luteinizing_hormone dbr:Relaxin_receptor dbr:Spermatogenesis dbr:Testicular_descent dbr:RXFP1 dbr:RXFP2 |
| dbp:altsymbols | H1 (en) H2, RLXH2, bA12D24.1.1, bA12D24.1.2 (en) ZINS4, RXN3, H3 (en) |
| dbp:arm | p (en) q (en) |
| dbp:band | 13.300000 (xsd:double) ter (en) |
| dbp:chromosome | 1 (xsd:integer) 9 (xsd:integer) 19 (xsd:integer) |
| dbp:entrezgene | 6013 (xsd:integer) 6019 (xsd:integer) 117579 (xsd:integer) |
| dbp:hgncid | 10026 (xsd:integer) 10027 (xsd:integer) 17135 (xsd:integer) |
| dbp:locussupplementarydata | -q12 (en) |
| dbp:name | Relaxin 3 (en) Insulin-like peptide 3 (en) Insulin-like peptide 5 (en) Relaxin 1 (en) Relaxin 2 (en) |
| dbp:omim | 179730 (xsd:integer) 179740 (xsd:integer) 606855 (xsd:integer) |
| dbp:pdb | 6 (xsd:integer) |
| dbp:refseq | NM_006911 (en) NM_080864 (en) NM_134441 (en) |
| dbp:symbol | INSL3 (en) INSL5 (en) RLN3 (en) RLN1 (en) RLN2 (en) |
| dbp:uniprot | P04090 (en) P04808 (en) Q8WXF3 (en) |
| dbp:wikiPageUsesTemplate | dbt:Further dbt:Hormones dbt:Reflist dbt:See_also dbt:Short_description dbt:Infobox_protein |
| dcterms:subject | dbc:Hormones_of_the_pregnant_female dbc:Hormones_of_the_ovary dbc:Human_female_endocrine_system dbc:Peptide_hormones dbc:Hormones_of_the_placenta |
| rdf:type | owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 dbo:Protein |
| rdfs:comment | Relaxin family peptide hormones in humans are represented by seven members: three relaxin-like (RLN) and four insulin-like (INSL) peptides: RLN1, RLN2, RNL3, INSL3, INSL4, INSL5, INSL6. This subdivision into two classes (RLN and INSL) is based primarily on early findings, and does not reflect the evolutionary origins or physiological differences between peptides. For example, it is known that the genes coding for RLN3 and INSL5 arose from one ancestral gene, and INSL3 shares origin with RLN2 and its multiple duplicates: RLN1, INSL4, INSL6. (en) |
| rdfs:label | Relaxin family peptide hormones (en) |
| rdfs:seeAlso | dbr:Insulin dbr:IGF dbr:Relaxin_family |
| owl:sameAs | freebase:Relaxin family peptide hormones wikidata:Relaxin family peptide hormones https://global.dbpedia.org/id/4u8qq |
| prov:wasDerivedFrom | wikipedia-en:Relaxin_family_peptide_hormones?oldid=1113655288&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/relaxin.png |
| foaf:isPrimaryTopicOf | wikipedia-en:Relaxin_family_peptide_hormones |
| foaf:name | Relaxin 3 (en) Insulin-like peptide 3 (en) Insulin-like peptide 5 (en) Relaxin 1 (en) Relaxin 2 (en) |
| is dbo:wikiPageRedirects of | dbr:Relaxin_family_peptides |
| is dbo:wikiPageWikiLink of | dbr:Relaxin-3 dbr:Alastair_MacLennan_(obstetrician) dbr:Relaxin dbr:Relaxin/insulin-like_family_peptide_receptor_1 dbr:Relaxin_receptor dbr:Relaxin_family_peptides |
| is foaf:primaryTopic of | wikipedia-en:Relaxin_family_peptide_hormones |
