Spiradenoma (original) (raw)
ورم الغدة العرقية (بالإنجليزية: Spiradenoma) (المعروف أيضًا بالورم الغدي المفرز للعرق أو الورم الغدي العرقي الناتح) هو حالة جلدية تتميز سريريا تماما بعقيدة جلدية غائرة وحيدة حوالي واحد سنتيمتر تحدث في السطح البطناني من الجسم، وتعتبر آفات الورم الغدي العرقي أوراما عرقية حميدة، وقد وصفت أيضا بأنها سرطان طلائي كيسي للغدد العرقية. ويعتبر المصدر النسيجي لهذا الورم محل جدل حتى الآن.
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| dbo:abstract | ورم الغدة العرقية (بالإنجليزية: Spiradenoma) (المعروف أيضًا بالورم الغدي المفرز للعرق أو الورم الغدي العرقي الناتح) هو حالة جلدية تتميز سريريا تماما بعقيدة جلدية غائرة وحيدة حوالي واحد سنتيمتر تحدث في السطح البطناني من الجسم، وتعتبر آفات الورم الغدي العرقي أوراما عرقية حميدة، وقد وصفت أيضا بأنها سرطان طلائي كيسي للغدد العرقية. ويعتبر المصدر النسيجي لهذا الورم محل جدل حتى الآن. (ar) El espiroadenoma, también llamado espiroadenoma ecrino, es un tipo de tumor benigno que afecta a la piel, sus células derivan de las glándulas sudoríparas ecrinas situadas en la piel. Se presenta como un nódulo superficial que puede aparecer en cualquier parte del cuerpo, es de crecimiento lento, color rojizo o azulado y consistencia dura. Suele alcanzar un tamaño de entre 1 y 3 cm de diámetro y tiene la particularidad de ser doloroso. El dolor puede ser espontáneo, aunque más frecuentemente es desencadenado por presión o contacto, es intenso pero de corta duración, habitualmente dura solo uno o dos minutos. Se trata de un tumor raro que fue descrito por primera vez en 1956 por y . Generalmente se presenta como un nódulo único solitario, en ocasiones existen lesiones múltiples que por su distribución pueden recordar al herpes zóster, distribución zosteriforme. El tratamiento recomendado es la cirugía con extirpación de la lesión. Excepcionalmente se han descrito en la literatura médica algunos casos en los que la tumoración se ha transformado en cáncer (espiradenocarcinomas ). (es) Spiradenomas (SA) are rare, benign cutaneous adnexal tumors that may progress to become their malignant counterparts, i.e. spiradenocarcinomas (SAC). Cutaneous adnexal tumors are a group of skin tumors consisting of tissues that have differentiated (i.e. matured from stem cells) towards one of the four primary adnexal structures found in normal skin: hair follicles, sebaceous sweat glands, apocrine sweat glands, and eccrine sweat glands. SA and SAC tumors were regarded as eccrine gland tumors and termed eccrine spiradenomas and eccrine spiradenocarcinomas, respectively. However, more recent studies have found them to be hair follicle tumors and commonly term them spiradenomas and spiradenocarcinomas, respectively. Further confusing the situation, SA-like and SAC-like tumors are also 1) manifestations of the inherited disorder, CYLD cutaneous syndrome (CCS), and 2) have repeatedly been confused with an entirely different tumor, adenoid cystic carcinomas of the salivary gland. Here, SA and SAC are strictly defined as sporadic hair follicle tumors that do not include the hereditary CCS spiradenomas and heridtary spiradenocarcinoms of CCS or the adenoid cystic carcinomas. SA tumors usually occur as slow-growing, single, small, nodular lesions located in the skin of the head, neck, or trunk. SAC tumors develop from benign SA tumors or in very rare cases begin as malignant tumors. SA and SAC tumors must be distinguished from the spiradenoma and spiradenocaricnoma tumors that develop in individuals afflicted with the CYLD cutaneous syndrome. CCS is an inherited disorder that commonly involves the development of multiple but on occasion a single or few tumors that closely resemble, and may be confused with, the sporadic SA and SAC tumors described here. CCS spiradenoma and CCS spiradenocarcinoma tumors must be distinguished form the sporadic SA and SAC tumors reviewed here in order to afford genetic counseling to individuals with CCS as well as to the close family members of these individuals. Currently, SA and SAC are usually treated by complete excision making sure that no tumor cells are left behind at the surgical site. This is particularly important in SAC where the incomplete surgical removal of all tumor cells may result in recurrence of the tumor at the surgical site and/or its metastasis to the local lymph nodes draining the surgical site and/or to distant tissues. In addition to surgical resection, some cases of SAC tumors have been treated with adjuvant therapy that includes radiotherapy and/or chemotherapy. It is not clear that these adjuvant treatments improve patient prognoses. Further studies are needed to determine the best treatment(s) for localize SA, localized SAC, and, in particular, metastatic SAC tumors. (en) |
| dbo:eMedicineSubject | article (en) |
| dbo:eMedicineTopic | 1062079 (en) |
| dbo:icd10 | ILDSC44.L40, C44.L64, D23.L49 |
| dbo:thumbnail | wiki-commons:Special:FilePath/Eccrine_spiradenoma_-_very_low_mag.jpg?width=300 |
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| dbo:wikiPageLength | 28322 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1094521070 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Sarcoma dbr:Epidermis dbr:Epithelioma dbr:List_of_cutaneous_neoplasms_associated_with_systemic_syndromes dbr:Mohs_surgery dbr:Meta-analysis dbr:Dermal_cylindroma dbr:Cylindroma dbr:Cytoplasm dbr:Vesicle_(biology_and_chemistry) dbr:Dermatology dbr:Dermis dbr:Invasion_(cancer) dbr:Genetic_counseling dbr:Cisplatin dbr:Granular_cell_tumor dbr:NF-κB dbr:Angiosarcoma dbr:Apoptosis dbr:Leiomyoma dbr:Liver_function_tests dbr:Lymph_node dbr:Magnetic_resonance_imaging dbr:Stem_cell dbr:Hemangioma dbr:Basal_cell_carcinoma dbr:Surgery dbr:Micrograph dbr:CT_scan dbr:Adjuvant_therapy dbr:Triamcinolone dbr:H&E_stain dbr:Eccrine_glands dbr:Trichoepithelioma dbr:Adenoid_cystic_carcinoma dbr:Etoposide dbr:Angiolipoma dbr:Basement_membrane dbr:Cell_nucleus dbr:Cellular_differentiation dbr:Transcription_factor dbr:ALPK1 dbr:Hair_follicles dbr:Histopathological dbc:Conditions_of_the_skin_appendages dbc:Epidermal_nevi,_neoplasms,_and_cysts dbr:Chemotherapy dbr:Trunk_(anatomy) dbr:Mitosis dbr:CYLD_(gene) dbr:CYLD_cutaneous_syndrome dbr:Positron_emission_tomography dbr:Apocrine_glands dbr:H&E dbr:Metastatic_adenocarcinoma dbr:Methotrexate dbr:Oncology dbr:Radiotherapy dbr:Sebaceous_glands dbr:Vascular_malformation dbr:Vulva dbr:Necroptosis dbr:Neuroma dbr:Lymphocyte dbr:Lymphovascular_invasion dbr:Malignant_acrospiroma dbr:Stratum_basale dbr:Venous_thrombosis dbr:List_of_cutaneous_conditions dbr:Surgical_margin dbr:Squamous_cell_carcinoma dbr:Chemotherapeutic_agent dbr:ILDS dbr:Leucocytes dbr:5-fluorouracil dbr:Adjuvant_radiation_therapy dbr:Malignant_melanoma dbr:Genitalia dbr:Botulinum_toxin_A dbr:CO2_laser |
| dbp:caption | Micrograph of a spiradenoma . H&E stain. (en) |
| dbp:emedicinesubj | article (en) |
| dbp:emedicinetopic | 1062079 (xsd:integer) |
| dbp:field | dbr:Dermatology dbr:Surgery dbr:Oncology |
| dbp:icd | ILDS C44.L40, C44.L64, D23.L49 (en) |
| dbp:name | Spiradenomas (en) |
| dbp:risks | development of malignant tumors (en) |
| dbp:symptoms | Solitary skin tumor (en) |
| dbp:synonyms | Eccrine spiradenoma (en) |
| dbp:wikiPageUsesTemplate | dbt:Infobox_medical_condition_(new) dbt:Medical_resources dbt:Reflist dbt:Tumors_of_skin_appendages |
| dcterms:subject | dbc:Conditions_of_the_skin_appendages dbc:Epidermal_nevi,_neoplasms,_and_cysts |
| gold:hypernym | dbr:Condition |
| rdf:type | owl:Thing wikidata:Q12136 yago:Abstraction100002137 yago:Attribute100024264 yago:Condition113920835 yago:Cyst114202996 yago:Disease114070360 yago:IllHealth114052046 yago:Illness114061805 yago:PathologicalState114051917 yago:Pathology114204950 yago:PhysicalCondition114034177 dbo:Disease yago:State100024720 yago:WikicatEpidermalNevi,Neoplasms,Cysts |
| rdfs:comment | ورم الغدة العرقية (بالإنجليزية: Spiradenoma) (المعروف أيضًا بالورم الغدي المفرز للعرق أو الورم الغدي العرقي الناتح) هو حالة جلدية تتميز سريريا تماما بعقيدة جلدية غائرة وحيدة حوالي واحد سنتيمتر تحدث في السطح البطناني من الجسم، وتعتبر آفات الورم الغدي العرقي أوراما عرقية حميدة، وقد وصفت أيضا بأنها سرطان طلائي كيسي للغدد العرقية. ويعتبر المصدر النسيجي لهذا الورم محل جدل حتى الآن. (ar) El espiroadenoma, también llamado espiroadenoma ecrino, es un tipo de tumor benigno que afecta a la piel, sus células derivan de las glándulas sudoríparas ecrinas situadas en la piel. Se presenta como un nódulo superficial que puede aparecer en cualquier parte del cuerpo, es de crecimiento lento, color rojizo o azulado y consistencia dura. Suele alcanzar un tamaño de entre 1 y 3 cm de diámetro y tiene la particularidad de ser doloroso. El dolor puede ser espontáneo, aunque más frecuentemente es desencadenado por presión o contacto, es intenso pero de corta duración, habitualmente dura solo uno o dos minutos. Se trata de un tumor raro que fue descrito por primera vez en 1956 por y . Generalmente se presenta como un nódulo único solitario, en ocasiones existen lesiones múltiples que por su (es) Spiradenomas (SA) are rare, benign cutaneous adnexal tumors that may progress to become their malignant counterparts, i.e. spiradenocarcinomas (SAC). Cutaneous adnexal tumors are a group of skin tumors consisting of tissues that have differentiated (i.e. matured from stem cells) towards one of the four primary adnexal structures found in normal skin: hair follicles, sebaceous sweat glands, apocrine sweat glands, and eccrine sweat glands. SA and SAC tumors were regarded as eccrine gland tumors and termed eccrine spiradenomas and eccrine spiradenocarcinomas, respectively. However, more recent studies have found them to be hair follicle tumors and commonly term them spiradenomas and spiradenocarcinomas, respectively. Further confusing the situation, SA-like and SAC-like tumors are also 1) man (en) |
| rdfs:label | ورم الغدة العرقية (ar) Espiroadenoma (es) Spiradenoma (en) |
| owl:sameAs | freebase:Spiradenoma yago-res:Spiradenoma wikidata:Spiradenoma dbpedia-ar:Spiradenoma dbpedia-es:Spiradenoma https://global.dbpedia.org/id/4vTmb |
| prov:wasDerivedFrom | wikipedia-en:Spiradenoma?oldid=1094521070&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Eccrine_spiradenoma_-_very_low_mag.jpg |
| foaf:isPrimaryTopicOf | wikipedia-en:Spiradenoma |
| foaf:name | Spiradenomas (en) |
| is dbo:wikiPageRedirects of | dbr:Spiradenocarcinoma dbr:Linear_eccrine_spiradenoma dbr:Eccrine_spiradenoma dbr:Malignant_eccrine_spiradenoma dbr:Malignant_spiradenoma dbr:Eruptive_syringomata dbr:Spiroma |
| is dbo:wikiPageWikiLink of | dbr:List_of_cutaneous_neoplasms_associated_with_systemic_syndromes dbr:Dermal_cylindroma dbr:CYLD_cutaneous_syndrome dbr:List_of_skin_conditions dbr:Spiradenocarcinoma dbr:Linear_eccrine_spiradenoma dbr:Eccrine_spiradenoma dbr:Malignant_eccrine_spiradenoma dbr:Malignant_spiradenoma dbr:Eruptive_syringomata dbr:Spiroma |
| is foaf:primaryTopic of | wikipedia-en:Spiradenoma |
