Stanozolol (original) (raw)
L'estanozolol, comercialitzat habitualment amb la marca Winstrol (oral) i Winstrol Depot (intramuscular), és un esteroide sintètic desenvolupat l'any 1962 per Winthrop Laboratories. És un derivat de la testosterona i ha estat aprovat per l'agència FDA per l'ús humà. L'estanozolol promou el desenvolupament muscular. En via oral és emprat per al tractament de l'angioedema hereditari i criofibrinogenemia.
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| dbo:abstract | L'estanozolol, comercialitzat habitualment amb la marca Winstrol (oral) i Winstrol Depot (intramuscular), és un esteroide sintètic desenvolupat l'any 1962 per Winthrop Laboratories. És un derivat de la testosterona i ha estat aprovat per l'agència FDA per l'ús humà. L'estanozolol promou el desenvolupament muscular. En via oral és emprat per al tractament de l'angioedema hereditari i criofibrinogenemia. (ca) Stanozol (zkratka. Stz), dostupný pod mnoha značkami, je androgenní a anabolický steroid (AAS), který byl odvozen od dihydrotestosteronu (DHT). Vyvinula jej americká farmaceutická společnost Winthrop Laboratories (Sterling Drug) v roce 1962 a byla schválena americkým úřadem pro potraviny a léčiva pro humánní použití, ačkoli dnes již není uváděna na trh v USA. Používá se také ve veterinární medicíně. Stanozolol byl většinou stažen a zůstává dostupný pouze v několika zemích. Je podáván orálně u lidí nebo injekcí do svalů u zvířat. Na rozdíl od většiny injekčních AAS, stanozolol není esterifikován a je prodáván jako vodná suspenze nebo v perorálním tabletu. Lék má vysokou orální biologickou dostupnost v důsledku alkylace C17a, která umožňuje hormonu přežít játrový metabolismus prvního průchodu po požití. Z tohoto důvodu se stanozolol také prodává ve formě tablet . Stanozolol je jedním z AAS běžně užívaných jako léky zvyšující výkon a je zakázáno používat v soutěži sportů pod záštitou Mezinárodní asociací atletických federací (IAAF) a mnoha dalších sportovních organizací. Navíc se stanozolol používá v amerických dostizích. (cs) Η στανοζολόλη (αγγλ. stanozolol, συντ. Stz), που πωλείται με διάφορες εμπορικές ονομασίες, είναι φάρμακο ανδρογόνων και ισχυρό αναβολικό στεροειδές (AAS) που προέρχεται από τη διϋδροτεστοστερόνη (DHT. Χρησιμοποιείται επίσης και για τη θεραπεία του κληρονομικού αγγειοοιδήματος. Αναπτύχθηκε από την αμερικανική φαρμακευτική εταιρεία Winthrop Laboratories (Sterling Drug) το 1962 και έχει εγκριθεί από την Αμερικανική Υπηρεσία Τροφίμων και Φαρμάκων για ανθρώπινη χρήση, αν και σήμερα δεν διατίθεται πλέον στις ΗΠΑ. Χρησιμοποιείται επίσης στην κτηνιατρική. Χορηγείται από το στόμα σε ανθρώπους ή με ενδομυϊκή ένεση σε ζώα. Είναι ένα από τα πιο διαδεδομένα αναβολικά φάρμακα που χρησιμοποιούνται, συνήθως ως φάρμακα που βελτιώνουν την αθλητική απόδοση και απαγορεύεται να χρησιμοποιείται σε διοργανώσεις υπό την αιγίδα της Διεθνούς Ένωσης IAAF και πολλών άλλων αθλητικών φορέων. Επιπλέον, η στανοζολόλη έχει περιοριστεί ιδιαίτερα στις ιπποδρομίες των ΗΠΑ. (el) Stanozolol ist ein synthetisches anaboles Steroid, das sich vom Testosteron ableitet. (de) Stanozolol (komerca nomo Winstrol) estas sintezita , kiu devenas el la testosterono. Ĝi estas uzata ĉefe kiel besta medicinaĵo, ĉefe ĉe , kaj ĉevaloj por stimuli la apetiton, pezkreskon, moskolan konstruon. Pro tiu lasta propreco, oni uzas ĝin kiel dopaĵon. Ĝi estis konata ĉefe dum la Someraj Olimpikoj de 1988, kiam la Ben Johnson senvulaiĝis kiel uzanto de stanozololo. (eo) El estanozolol, comúnmente vendido bajo el nombre de Winstrol (oral) y Winstrol Depot (intramuscular), es un esteroide anabólico sintético derivado de la dihidrotestosterona. Fue desarrollado por Winthrop Laboratorios en 1962 y ha sido aprobado por la FDA para el uso humano. Es un fármaco que pertenece al grupo de los andrógenos atenuados. Se trata de un anabolizante que estimula la síntesis proteica y cuyo efecto se manifiesta en un aumento del apetito y el sabor de los alimentos y del índice de masa corporal. (es) Le stanozolol, généralement vendu sous le nom de Winstrol ou Stanabol, est un stéroïde anabolisant synthétique dérivé de la testostérone. Le stanozolol est utilisé chez l'homme pour le traitement de l'anémie et de l'angio-œdème héréditaire. Il est également utilisé chez l'animal pour stimuler le développement musculaire, la production de globule rouge, la densité des os ou l'appétit d'animaux affaiblis. Le stanozolol est couramment utilisé en tant que substance ergogénique. Il est interdit dans les compétitions sportives. (fr) Stanozolol (abbrev. Stz), sold under many brand names, is an androgen and anabolic steroid (AAS) medication derived from dihydrotestosterone (DHT). It is used to treat hereditary angioedema. It was developed by American pharmaceutical company Winthrop Laboratories (Sterling Drug) in 1962, and has been approved by the U.S. Food and Drug Administration for human use, though it is no longer marketed in the USA. It is also used in veterinary medicine. Stanozolol has mostly been discontinued, and remains available in only a few countries. It is given by mouth in humans or by injection into muscle in animals. Unlike most injectable AAS, stanozolol is not esterified and is sold as an aqueous suspension, or in oral tablet form. The drug has a high oral bioavailability, due to a C17α alkylation which allows the hormone to survive first-pass liver metabolism when ingested. It is because of this that stanozolol is also sold in tablet form. Stanozolol is one of the AAS commonly used as performance-enhancing drugs and is banned from use in sports competition under the auspices of the International Association of Athletics Federations (IAAF) and many other sporting bodies. It is an anabolic steroid that is known to have a diuretic effect. Additionally, stanozolol has been highly restricted in US horse racing. (en) Lo stanozololo, noto anche commercialmente come Winstrol, è un derivato sintetico del testosterone caratterizzato, rispetto a questo, da minori effetti androgeni e da un'azione anabolizzante quattro o cinque volte superiore e per tale motivo, nella pratica terapeutica, viene preferito alle oltre cento molecole derivate dal testosterone. Lo stanozololo presenta un'alchilazione in posizione C 17 alfa che lo rende idoneo nel trattamento intrarticolare della DJD in quanto lo protegge dall'azione dell'enzima aromatasi. Lo stanozololo viene spesso usato per scopi illeciti (doping) a dosaggi elevatissimi: nelle palestre si parla di un impiego del dosaggio terapeutico, moltiplicato sino a 15 volte. Questo steroide resta invece, sempre a livello nazionale, un farmaco di elezione per determinate patologie in campo veterinario, in cui abbonda una letteratura medica oggettiva, non improntata a giudizi di stampo mediatico-giornalistico, ma a valutazioni di carattere strettamente sanitario. (it) スタノゾロール (Stanozolol) は、ジヒドロテストステロン由来のアナボリックステロイドである。ウィンストロール（経口）やウィンストロール・デポ（筋肉）の名称で商業的に販売されている。1962年にアメリカ食品医薬品局（FDA）に認可された。 (ja) Stanozolol (Handelsnamen Stromba, Stanol; of Winstrol) is een synthetisch anabole steroïde, dat van dihydrotestosteron is afgeleid. Het werd geoctrooieerd door Sterling Drug Inc. in 1962 Het wordt hoofdzakelijk gebruikt in de veterinaire geneeskunde, om de eetlust, gewichtstoename en spiervorming te stimuleren bij onder meer honden, katten of paarden. (nl) O estanozolol, geralmente vendido com o nome de Winstrol (oral) e Winstrol Depot (intramuscular), foi desenvolvido pelos em 1962. É um esteroide anabolizante sintético derivado da testosterona, e foi aprovado pela FDA (Food and Drug Administration) nos Estados Unidos para uso em humanos. Hoje em dia existem vários laboratórios produzindo esta substância, é o caso da Desma na Espanha, Pharmacia & Upjohn nos Estados Unidos e outras. Ao contrário da maioria dos esteroides anabólicos injetáveis, o estanozolol não é esterificado e é vendido em uma suspensão aquosa, ou em comprimidos na forma oral. A droga tem uma grande biodisponibilidade, devido à C17 α-alquilação que permite ao hormônio a sua sobrevivência ao passar pelo metabolismo do fígado quando é ingerido. É por causa deste motivo que ele também é vendido em comprimidos. O estanozolol tem sido utilizado em pacientes humanos e em animais para diversas condições. Em humanos foi demonstrado seu sucesso no tratamento da anemia e angioedema hereditário. Veterinários podem prescrever a droga para melhorar o crescimento muscular, produção de células vermelhas do sangue, aumentar a densidade óssea e estimular o apetite de animais fracos ou debilitados. O estanozolol é um dos esteroides anabolizantes geralmente usados como agentes ergogênicos e é banido do uso em competições esportivas sob as regras da International Association of Athletics Federations (IAAF). (pt) Stanozolol är en syntetisk anabolisk steroid utvunnen ur Dihydrotestosteron (DHT). Sprinten Ben Johnson tog Stanozolol. (sv) Станозоло́л — анаболический стероидный препарат, производное дигидротестостерона (отличается замещенной на +3,2-пиразол карбонильной группой 3-ей позиции и метилом в 17α-позиции). Станозолол является антагонистом прогестерона. Полностью запрещённый к применению в спорте препарат, неофициально используется спортсменами в качестве допинга, а также в бодибилдинге, боксе, спортивной борьбе, смешанных единоборствах, лёгкой атлетике, тяжёлой атлетике и во многих других видах спорта. Использовался также как допинг для скаковых лошадей. (ru) 康力龙也称司坦唑醇（Stanozolol），雄激素类药物。白色粉末状无臭。几乎不溶于水，能溶于油脂。用于慢性消耗性疾病、纠正重症术后消瘦负氮平衡、男性性腺功能减退、骨质疏松症、小儿发育不良、再生障碍性贫血、术后深静脉血栓、白血病前期逆转治疗等。具肝毒性、血脂紊乱、痤疮、女性雄性化、男性性腺萎缩等副作用。 (zh) |
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| dbp:excretion | Urine: 84% (en) |
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| rdfs:comment | L'estanozolol, comercialitzat habitualment amb la marca Winstrol (oral) i Winstrol Depot (intramuscular), és un esteroide sintètic desenvolupat l'any 1962 per Winthrop Laboratories. És un derivat de la testosterona i ha estat aprovat per l'agència FDA per l'ús humà. L'estanozolol promou el desenvolupament muscular. En via oral és emprat per al tractament de l'angioedema hereditari i criofibrinogenemia. (ca) Stanozolol ist ein synthetisches anaboles Steroid, das sich vom Testosteron ableitet. (de) Stanozolol (komerca nomo Winstrol) estas sintezita , kiu devenas el la testosterono. Ĝi estas uzata ĉefe kiel besta medicinaĵo, ĉefe ĉe , kaj ĉevaloj por stimuli la apetiton, pezkreskon, moskolan konstruon. Pro tiu lasta propreco, oni uzas ĝin kiel dopaĵon. Ĝi estis konata ĉefe dum la Someraj Olimpikoj de 1988, kiam la Ben Johnson senvulaiĝis kiel uzanto de stanozololo. (eo) El estanozolol, comúnmente vendido bajo el nombre de Winstrol (oral) y Winstrol Depot (intramuscular), es un esteroide anabólico sintético derivado de la dihidrotestosterona. Fue desarrollado por Winthrop Laboratorios en 1962 y ha sido aprobado por la FDA para el uso humano. Es un fármaco que pertenece al grupo de los andrógenos atenuados. Se trata de un anabolizante que estimula la síntesis proteica y cuyo efecto se manifiesta en un aumento del apetito y el sabor de los alimentos y del índice de masa corporal. (es) Le stanozolol, généralement vendu sous le nom de Winstrol ou Stanabol, est un stéroïde anabolisant synthétique dérivé de la testostérone. Le stanozolol est utilisé chez l'homme pour le traitement de l'anémie et de l'angio-œdème héréditaire. Il est également utilisé chez l'animal pour stimuler le développement musculaire, la production de globule rouge, la densité des os ou l'appétit d'animaux affaiblis. Le stanozolol est couramment utilisé en tant que substance ergogénique. Il est interdit dans les compétitions sportives. (fr) スタノゾロール (Stanozolol) は、ジヒドロテストステロン由来のアナボリックステロイドである。ウィンストロール（経口）やウィンストロール・デポ（筋肉）の名称で商業的に販売されている。1962年にアメリカ食品医薬品局（FDA）に認可された。 (ja) Stanozolol (Handelsnamen Stromba, Stanol; of Winstrol) is een synthetisch anabole steroïde, dat van dihydrotestosteron is afgeleid. Het werd geoctrooieerd door Sterling Drug Inc. in 1962 Het wordt hoofdzakelijk gebruikt in de veterinaire geneeskunde, om de eetlust, gewichtstoename en spiervorming te stimuleren bij onder meer honden, katten of paarden. (nl) Stanozolol är en syntetisk anabolisk steroid utvunnen ur Dihydrotestosteron (DHT). Sprinten Ben Johnson tog Stanozolol. (sv) Станозоло́л — анаболический стероидный препарат, производное дигидротестостерона (отличается замещенной на +3,2-пиразол карбонильной группой 3-ей позиции и метилом в 17α-позиции). Станозолол является антагонистом прогестерона. Полностью запрещённый к применению в спорте препарат, неофициально используется спортсменами в качестве допинга, а также в бодибилдинге, боксе, спортивной борьбе, смешанных единоборствах, лёгкой атлетике, тяжёлой атлетике и во многих других видах спорта. Использовался также как допинг для скаковых лошадей. (ru) 康力龙也称司坦唑醇（Stanozolol），雄激素类药物。白色粉末状无臭。几乎不溶于水，能溶于油脂。用于慢性消耗性疾病、纠正重症术后消瘦负氮平衡、男性性腺功能减退、骨质疏松症、小儿发育不良、再生障碍性贫血、术后深静脉血栓、白血病前期逆转治疗等。具肝毒性、血脂紊乱、痤疮、女性雄性化、男性性腺萎缩等副作用。 (zh) Stanozol (zkratka. Stz), dostupný pod mnoha značkami, je androgenní a anabolický steroid (AAS), který byl odvozen od dihydrotestosteronu (DHT). Vyvinula jej americká farmaceutická společnost Winthrop Laboratories (Sterling Drug) v roce 1962 a byla schválena americkým úřadem pro potraviny a léčiva pro humánní použití, ačkoli dnes již není uváděna na trh v USA. Používá se také ve veterinární medicíně. Stanozolol byl většinou stažen a zůstává dostupný pouze v několika zemích. Je podáván orálně u lidí nebo injekcí do svalů u zvířat. (cs) Η στανοζολόλη (αγγλ. stanozolol, συντ. Stz), που πωλείται με διάφορες εμπορικές ονομασίες, είναι φάρμακο ανδρογόνων και ισχυρό αναβολικό στεροειδές (AAS) που προέρχεται από τη διϋδροτεστοστερόνη (DHT. Χρησιμοποιείται επίσης και για τη θεραπεία του κληρονομικού αγγειοοιδήματος. (el) Stanozolol (abbrev. Stz), sold under many brand names, is an androgen and anabolic steroid (AAS) medication derived from dihydrotestosterone (DHT). It is used to treat hereditary angioedema. It was developed by American pharmaceutical company Winthrop Laboratories (Sterling Drug) in 1962, and has been approved by the U.S. Food and Drug Administration for human use, though it is no longer marketed in the USA. It is also used in veterinary medicine. Stanozolol has mostly been discontinued, and remains available in only a few countries. It is given by mouth in humans or by injection into muscle in animals. (en) Lo stanozololo, noto anche commercialmente come Winstrol, è un derivato sintetico del testosterone caratterizzato, rispetto a questo, da minori effetti androgeni e da un'azione anabolizzante quattro o cinque volte superiore e per tale motivo, nella pratica terapeutica, viene preferito alle oltre cento molecole derivate dal testosterone. Lo stanozololo presenta un'alchilazione in posizione C 17 alfa che lo rende idoneo nel trattamento intrarticolare della DJD in quanto lo protegge dall'azione dell'enzima aromatasi. (it) O estanozolol, geralmente vendido com o nome de Winstrol (oral) e Winstrol Depot (intramuscular), foi desenvolvido pelos em 1962. É um esteroide anabolizante sintético derivado da testosterona, e foi aprovado pela FDA (Food and Drug Administration) nos Estados Unidos para uso em humanos. Hoje em dia existem vários laboratórios produzindo esta substância, é o caso da Desma na Espanha, Pharmacia & Upjohn nos Estados Unidos e outras. (pt) |
| rdfs:label | Estanozolol (ca) Stanozolol (cs) Stanozolol (de) Στανοζολόλη (el) Stanozololo (eo) Estanozolol (es) Stanozolol (fr) Stanozololo (it) スタノゾロール (ja) Stanozolol (nl) Stanozolol (en) Станозолол (ru) Estanozolol (pt) Stanozolol (sv) 康力龙 (zh) |
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