Suparnostic (original) (raw)
suPARnostic is a simplified double monoclonal antibody sandwich enzyme-linked immunosorbent assay (ELISA) that measures the amount of soluble urokinase plasminogen activator receptor (suPAR) in blood. Elevated plasma suPAR levels have been observed in various infectious, inflammatory and autoimmune diseases. suPAR concentration positively correlates to the activation level of the immune system. suPARnostic can be used as a prognostic tool to determine the severity of a disease within a patient, but is not used as a reliable diagnostic tool, as it can detect the severity of the immune response in a patient, but does not reveal the specific disease from which the patient may be suffering. Recently, increase suPAR levels were shown to be associated with increased risk of systemic inflammatory
| Property | Value |
|---|---|
| dbo:abstract | suPARnostic is a simplified double monoclonal antibody sandwich enzyme-linked immunosorbent assay (ELISA) that measures the amount of soluble urokinase plasminogen activator receptor (suPAR) in blood. Elevated plasma suPAR levels have been observed in various infectious, inflammatory and autoimmune diseases. suPAR concentration positively correlates to the activation level of the immune system. suPARnostic can be used as a prognostic tool to determine the severity of a disease within a patient, but is not used as a reliable diagnostic tool, as it can detect the severity of the immune response in a patient, but does not reveal the specific disease from which the patient may be suffering. Recently, increase suPAR levels were shown to be associated with increased risk of systemic inflammatory response syndrome (SIRS)/sepsis, cardiovascular disease, type 2 diabetes, infectious diseases, HIV, cancer tuberculosis, malaria, bacterial and viral CNS infections, rheumatoid arthritis, multiple sclerosis and mortality in the general population. (en) |
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| dbo:wikiPageWikiLink | dbr:Calibration_curve dbr:Cancer dbr:Mortality_rate dbr:Polyclonal_antibodies dbr:Blood_brain_barrier dbr:Rheumatoid_arthritis dbr:ELISA dbr:Inflammation dbr:Monoclonal_antibodies dbr:Monoclonal_antibody dbr:Multiple_sclerosis dbr:Opportunistic_infection dbr:Antibody dbr:Malaria dbr:SuPAR dbr:Microtiter_plate dbr:Tuberculosis dbr:Type_2_diabetes dbr:HIV dbr:3,3',5,5'-Tetramethylbenzidine dbr:Cardiovascular_disease dbc:Blood_tests dbr:Absorbance dbr:Homogeneity_and_heterogeneity dbr:In_vitro_diagnostics dbr:Autoimmune_diseases dbr:Sepsis dbr:Infectious_disease dbr:Systemic_inflammatory_response_syndrome dbr:Shelf_life dbr:Urine dbr:Immune_system dbr:Infectious_diseases dbr:Cerebral_spinal_fluid dbr:CNS_infection |
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| dct:subject | dbc:Blood_tests |
| gold:hypernym | dbr:Antibody |
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| rdfs:comment | suPARnostic is a simplified double monoclonal antibody sandwich enzyme-linked immunosorbent assay (ELISA) that measures the amount of soluble urokinase plasminogen activator receptor (suPAR) in blood. Elevated plasma suPAR levels have been observed in various infectious, inflammatory and autoimmune diseases. suPAR concentration positively correlates to the activation level of the immune system. suPARnostic can be used as a prognostic tool to determine the severity of a disease within a patient, but is not used as a reliable diagnostic tool, as it can detect the severity of the immune response in a patient, but does not reveal the specific disease from which the patient may be suffering. Recently, increase suPAR levels were shown to be associated with increased risk of systemic inflammatory (en) |
| rdfs:label | Suparnostic (en) |
| owl:sameAs | freebase:Suparnostic yago-res:Suparnostic wikidata:Suparnostic https://global.dbpedia.org/id/4vMf7 |
| prov:wasDerivedFrom | wikipedia-en:Suparnostic?oldid=1057767432&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Suparnostic |
| is foaf:primaryTopic of | wikipedia-en:Suparnostic |