Long-term single-cell imaging of mammalian stem cells (original) (raw)

• Barker, N. et al. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6, 25–36 (2010).
  Article CAS Google Scholar
• Barker, N. et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449, 1003–1007 (2007).
  Article CAS Google Scholar
• Benveniste, P. et al. Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential. Cell Stem Cell 6, 48–58 (2010).
  Article CAS Google Scholar
• Kiel, M.J. et al. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121, 1109–1121 (2005).
  Article CAS Google Scholar
• Osawa, M., Hanada, K., Hamada, H. & Nakauchi, H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273, 242–245 (1996).
  Article CAS Google Scholar
• Shackleton, M. et al. Generation of a functional mammary gland from a single stem cell. Nature 439, 84–88 (2006).
  Article CAS Google Scholar
• Stingl, J. et al. Purification and unique properties of mammary epithelial stem cells. Nature 439, 993–997 (2006).
  Article CAS Google Scholar
• Dykstra, B. et al. Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell 1, 218–229 (2007).
  Article CAS Google Scholar
• Lemischka, I.R., Raulet, D.H. & Mulligan, R.C. Developmental potential and dynamic behavior of hematopoietic stem cells. Cell 45, 917–927 (1986).
  Article CAS Google Scholar
• Schroeder, T. Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior. Cell Stem Cell 6, 203–207 (2010).
  Article CAS Google Scholar
• Chang, H.H., Hemberg, M., Barahona, M., Ingber, D.E. & Huang, S. Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature 453, 544–547 (2008).
  Article CAS Google Scholar
• Cross, M.A. et al. Expression of lineage restricted transcription factors precedes lineage specific differentiation in a multipotent haemopoietic progenitor cell line. Oncogene 9, 3013–3016 (1994).
  CAS PubMed Google Scholar
• Graf, T. & Enver, T. Forcing cells to change lineages. Nature 462, 587–594 (2009).
  Article CAS Google Scholar
• Chambers, I. et al. Nanog safeguards pluripotency and mediates germline development. Nature 450, 1230–1234 (2007).
  Article CAS Google Scholar
• Huang, S. Non-genetic heterogeneity of cells in development: more than just noise. Development 136, 3853–3862 (2009).
  Article CAS Google Scholar
• Spiller, D.G., Wood, C.D., Rand, D.A. & White, M.R. Measurement of single-cell dynamics. Nature 465, 736–745 (2010).
  Article CAS Google Scholar
• Rieger, M.A. & Schroeder, T. Exploring hematopoiesis at single cell resolution. Cells Tissues Organs 188, 139–149 (2008).
  Article Google Scholar
• Schroeder, T. Tracking hematopoiesis at the single cell level. Ann. NY Acad. Sci. 1044, 201–209 (2005).
  Article Google Scholar
• Schroeder, T. Imaging stem-cell-driven regeneration in mammals. Nature 453, 345–351 (2008).
  Article CAS Google Scholar
• Schroeder, T. The electronic crystal ball: predicting cell fate from time-lapse data. Nat. Methods 7, 190–191 (2010).
  Article CAS Google Scholar
• Eilken, H.M., Nishikawa, S. & Schroeder, T. Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature 457, 896–900 (2009).
  Article CAS Google Scholar
• Rieger, M.A., Hoppe, P.S., Smejkal, B.M., Eitelhuber, A.C. & Schroeder, T. Hematopoietic cytokines can instruct lineage choice. Science 325, 217–218 (2009).
  Article CAS Google Scholar
• Megason, S.G. & Fraser, S.E. Imaging in systems biology. Cell 130, 784–795 (2007).
  Article CAS Google Scholar
• Rieger, M.A. & Schroeder, T. Analyzing cell fate control by cytokines through continuous single cell biochemistry. J. Cell. Biochem. 108, 343–352 (2009).
  Article CAS Google Scholar
• Baker, M. Cellular imaging: taking a long, hard look. Nature 466, 1137–1140 (2010).
  Article CAS Google Scholar
• Cohen, A.R., Gomez, F.L.A., Roysam, B. & Cayouette, M. Computational prediction of neural progenitor cell fates. Nat. Methods 7, 213–218 (2010).
  Article CAS Google Scholar
• Kuang, S., Kuroda, K., Le Grand, F. & Rudnicki, M.A. Asymmetric self-renewal and commitment of satellite stem cells in muscle. Cell 129, 999–1010 (2007).
  Article CAS Google Scholar
• Costa, M. et al. Continuous live imaging of adult neural stem cell division and lineage progression in vitro. Development 138, 1057–1068 (2011).
  Article CAS Google Scholar
• Costa, M.R., Bucholz, O., Schroeder, T. & Gotz, M. Late origin of glia-restricted progenitors in the developing mouse cerebral cortex. Cereb. Cortex 19 Suppl 1, i135–i143 (2009).
  Article Google Scholar
• Dykstra, B. et al. High-resolution video monitoring of hematopoietic stem cells cultured in single-cell arrays identifies new features of self-renewal. Proc. Natl. Acad. Sci. USA 103, 8185–8190 (2006).
  Article CAS Google Scholar
• Shen, Q. et al. The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells. Nat. Neurosci. 9, 743–751 (2006).
  Article CAS Google Scholar
• Costa, M.R., Wen, G., Lepier, A., Schroeder, T. & Gotz, M. Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex. Development 135, 11–22 (2008).
  Article CAS Google Scholar
• Kimura, A. et al. The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis. Blood 114, 4721–4728 (2009).
  Article CAS Google Scholar
• Ravin, R. et al. Potency and fate specification in CNS stem cell populations in vitro. Cell Stem Cell 3, 670–680 (2008).
  Article CAS Google Scholar
• Berninger, B. et al. Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia. J. Neurosci. 27, 8654–8664 (2007).
  Article CAS Google Scholar
• Heinrich, C. et al. Directing astroglia from the cerebral cortex into subtype specific functional neurons. PLoS Biol. 8, e1000373 (2010).
  Article Google Scholar
• Heinrich, C. et al. Generation of subtype specific neurons from postnatal astroglia of the mouse cerebral cortex. Nat. Protoc. 6, 214–228 (2011).
  Article CAS Google Scholar
• Warlich, E. et al. Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming. Mol. Ther. advance online publication, doi:10.1038/mt.2010.314 (1 February 2011).
  Article CAS Google Scholar
• Ntziachristos, V. Going deeper than microscopy: the optical imaging frontier in biology. Nat. Methods 7, 603–614 (2010).
  Article CAS Google Scholar
• Tsien, R.Y. Imagining imaging's future. Nat. Rev. Mol. Cell Biol. 4 (suppl.), SS16–SS21 (2003).
  Google Scholar
• Stadtfeld, M., Varas, F. & Graf, T. Fluorescent protein-cell labeling and its application in time-lapse analysis of hematopoietic differentiation. Methods Mol. Med. 105, 395–412 (2005).
  CAS PubMed Google Scholar
• Rothbauer, U. et al. Targeting and tracing antigens in live cells with fluorescent nanobodies. Nat. Methods 3, 887–889 (2006).
  Article CAS Google Scholar
• Shaner, N.C., Steinbach, P.A. & Tsien, R.Y. A guide to choosing fluorescent proteins. Nat. Methods 2, 905–909 (2005).
  Article CAS Google Scholar
• Pantazis, P., Maloney, J., Wu, D. & Fraser, S.E. Second harmonic generating (SHG) nanoprobes for in vivo imaging. Proc. Natl. Acad. Sci. USA 107, 14535–14540 (2010).
  Article CAS Google Scholar
• Eilken, H.M. et al. Continuous long-term detection of live cell surface markers by 'in culture' antibody staining. Protoc. Exchange doi:10.1038/protex.2011.205 (published online 28 January 2011).
• Cappello, S. et al. The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nat. Neurosci. 9, 1099–1107 (2006).
  Article CAS Google Scholar
• Collins, T.J. ImageJ for microscopy. Biotechniques 43, 25–30 (2007).
  Article Google Scholar
• Lamprecht, M.R., Sabatini, D.M. & Carpenter, A.E. CellProfiler: free, versatile software for automated biological image analysis. Biotechniques 42, 71–75 (2007).
  Article CAS Google Scholar
• Macarthur, B.D., Ma'ayan, A. & Lemischka, I.R. Systems biology of stem cell fate and cellular reprogramming. Nat. Rev. Mol. Cell Biol. 10, 672–681 (2009).
  Article CAS Google Scholar
• Whichard, Z.L., Sarkar, C.A., Kimmel, M. & Corey, S.J. Hematopoiesis and its disorders: a systems biology approach. Blood 115, 2339–2347 (2010).
  Article CAS Google Scholar