FAM3B (original) (raw)
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Protein-coding gene in the species Homo sapiens
| FAM3B | |
|---|---|
| Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YOP, 2YOQ | |
| Identifiers | |
| Aliases | FAM3B, 2-21, C21orf11, C21orf76, ORF9, PANDER, PRED44, family with sequence similarity 3 member B, FAM3 metabolism regulating signaling molecule B |
| External IDs | OMIM: 608617; MGI: 1270150; HomoloGene: 10766; GeneCards: FAM3B; OMA:FAM3B - orthologs |
Gene location (Human) Chr.Chromosome 21 (human)[1]   Band21q22.3Start41,304,212 bp[1]End41,357,727 bp[1] |
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Gene location (Mouse) Chr.Chromosome 16 (mouse)[2] Band16 C4|16 57.47 cMStart97,272,165 bp[2]End97,316,016 bp[2] |
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| RNA expression patternBgeeHuman Mouse (ortholog)Top expressed inmucosa of ileumparotid glandjejunal mucosaduodenumbody of pancreaspancreatic epithelial cellpancreatic ductal celloral cavityolfactory zone of nasal mucosacorpus epididymisTop expressed ingastric mucosaepithelium of stomachpyloric antrummucous cell of stomachseminal vesiculaduodenumjejunumleft colonintestinal villusseminiferous tubuleMore reference expression dataBioGPSn/a | |
| Gene ontologyMolecular function cytokine activity Cellular component extracellular region extracellular exosome extracellular space Biological process insulin secretion apoptotic process regulation of signaling receptor activity glucose homeostasis signal transduction Sources:Amigo / QuickGO | |
| OrthologsSpeciesHuman MouseEntrez5409752793EnsemblENSG00000183844ENSMUSG00000022938UniProtP58499Q9D309RefSeq (mRNA)NM_058186NM_206964NM_020622RefSeq (protein)NP_478066NP_996847NP_065647Location (UCSC)Chr 21: 41.3 – 41.36 MbChr 16: 97.27 – 97.32 MbPubMed search[3][4] | |
| Wikidata | |
| View/Edit HumanView/Edit Mouse |
Protein FAM3B is a protein that in humans is encoded by the FAM3B gene.[5]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000183844 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022938 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: FAM3B family with sequence similarity 3, member B".
Yang J, Robert CE, Burkhardt BR, Young RA, Wu J, Gao Z, Wolf BA (November 2005). "Mechanisms of glucose-induced secretion of pancreatic-derived factor (PANDER or FAM3B) in pancreatic beta-cells". Diabetes. 54 (11): 3217–28. doi:10.2337/diabetes.54.11.3217. PMID 16249448.
Yang J, Gao Z, Robert CE, Burkhardt BR, Gaweska H, Wagner A, Wu J, Greene SR, Young RA, Wolf BA (August 2005). "Structure-function studies of PANDER, an islet specific cytokine inducing cell death of insulin-secreting beta cells". Biochemistry. 44 (34): 11342–52. doi:10.1021/bi0503908. PMID 16114871.
Zhu Y, Xu G, Patel A, McLaughlin MM, Silverman C, Knecht K, Sweitzer S, Li X, McDonnell P, Mirabile R, Zimmerman D, Boyce R, Tierney LA, Hu E, Livi GP, Wolf B, Abdel-Meguid SS, Rose GD, Aurora R, Hensley P, Briggs M, Young PR (August 2002). "Cloning, expression, and initial characterization of a novel cytokine-like gene family". Genomics. 80 (2): 144–50. doi:10.1006/geno.2002.6816. PMID 12160727.
Reymond A, Friedli M, Henrichsen CN, Chapot F, Deutsch S, Ucla C, Rossier C, Lyle R, Guipponi M, Antonarakis SE (November 2001). "From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map". Genomics. 78 (1–2): 46–54. doi:10.1006/geno.2001.6640. PMID 11707072.
PDBe-KB provides an overview of all the structure information available in the PDB for Mouse Protein FAM3B