Arlette Setiawan | Universitas Padjadjaran (original) (raw)

Papers by Arlette Setiawan

European Journal of Dentistry, Dec 13, 2022

Objective Stunting is the impaired growth and development children experience from chronic malnut... more Objective Stunting is the impaired growth and development children experience from chronic malnutrition and repeated infection that cause long-term damage. Malnutrition for a long time will affect the shape and composition of bones and teeth, making children more vulnerable to dental health problems. Preschoolers with sufficiently active consumption can choose the food they like delightful foods so that it can increase the risk of caries. Based on data from the Bandung City Health Office in 2019, 161 toddlers (25.43%) in Sukawarna Village experienced stunting. This study analyzed the relationship between eating behavior and caries experience in stunting children in Sukawarna Village, Sukajadi District. Materials and Methods This study uses a quantitative descriptive research method with a secondary data analysis approach from the documentation of the Universitas Padjadjaran Academic Leadership Grant data with the title "Aspects of jaw growthdevelopment and family approach in early detection and prevention of stunting." Sampling used purposive sampling specifically for preschool children with a sample size of 80 respondents. The data obtained will be processed and then analyzed using the Spearman Rank correlation statistical test. Results Sixty-three percent of respondents have poor eating behavior, and the majority (80.35%) have cavities due to caries (decay). Spearman Rank correlation coefficient is À0.145 and significance is 0.0983. Conclusion Overall eating behavior is related to the caries experience in stunting children. Consumption of cariogenic foods influences the caries experience.

F1000Research, Jun 21, 2023

Background: Mother's education is a key demographic in determining a healthy child. Education is ... more Background: Mother's education is a key demographic in determining a healthy child. Education is important and may indirectly affect how well children eat by changing parents' attitudes and practices. Therefore, this study aims to analyze the association between maternal education and parenting practice with stunting among children under five. Methods: This study used a cross-sectional study of mothers with children under five in Indonesia, specifically conducted in six rural areas in West Java province. This study employs bivariate analysis with Spearman and binary logistic regression. Results: Among 733 children under five, we found that 24.01% of these children were stunted. The mother's educational background, stunting knowledge, and parenting practice showed no significant change (p > 0.5). Moreover, the binary logistic linear analysis showed that education levels, knowledge about stunting, and mothers' behaviour toward parenting practices are not significantly related to stunting (p > .05). Conclusion: Maternal education and parenting practice is not a determinant of stunting in children under five in West Java, Indonesia, and this contradicts earlier studies. However, further research is needed to confirm these findings and explore the complex interplay of social, cultural, and economic factors that contribute to stunting in Open Peer Review Approval Status

Jurnal keperawatan Padjadjaran, Jul 17, 2023

Stunting remains a public health burden in Indonesia. National strategy and coordination of accel... more Stunting remains a public health burden in Indonesia. National strategy and coordination of acceleration implementation for stunting reduction have been applied. The transdisciplinary approach is essential to improving the effectiveness and efficiency of all levels of participating in stunting programs. This transdisciplinary approach is expected to solve stunting problems from upstream to downstream and provide innovations based on local and national needs. In creating a stunting-free area, a transdisciplinary approach not only decreases stunting prevalence but also sustains children's health status.

Journal of Multidisciplinary Healthcare

It is widely acknowledged that the socioeconomic circumstances of a family income are correctly r... more It is widely acknowledged that the socioeconomic circumstances of a family income are correctly reflected in that family expenditures. The dietary habits of families are influenced by socioeconomic circumstances that may affect stunting. Therefore, this study aims to investigate the household economic predictor stunting (mother's employment, family income, and family expenditure) in children under five. Methods: This study used a cross-sectional design. Six districts and cities have been chosen as study areas based on the areas with the highest incidence of stunting in West Java, Indonesia. This study conducted specifically from October to December 2018. Data were examined using descriptive statistics (frequency distribution) and a Spearman Rank bivariate test. A logistic regression was employed to determine the elements that serve as predictors of stunting. Results: A total of 731 women with children under five participated in the study. A bivariate analysis showed that mother's employment had an association with stunting among children under five (p = 0.014). Meanwhile, family income and expenditure are not statistically significant associated with stunting (p > 0.05). A multivariate analysis showed that mother's employment was a stunting predictor with odd ratio (OR) 1.810 (p = 0.017). The OR value means that mothers who do not work have a 1.810 chance for their children to experience stunting compared with mothers who have work. However, family income and expenditure have negative projected values (p = 0.580 and p = 0.398, respectively). Conclusion: Children under five who are stunted are potentially predictive with mothers' employment, with a chance is higher in mother who do not work. However, family income and expenditure are not predictive of stunting.

Cerebral palsy is a group of permanent movement disorders that appear in early childhood with a v... more Cerebral palsy is a group of permanent movement disorders that appear in early childhood with a vary signs andsymptomsincludepoorcoordination, stiffmuscles, weak muscles, and tremors.This case report aims to provide clinicians with general description of dental and oral health care for children with cerebral palsy under general anesthesia. A 3.5-year-old boy came with his parents to Al Ihsan General Hospital, complaining of many cavities in their child’s teeth. The patient has been diagnosed by a pediatrician with cerebral palsy type spastic quadriplegia. Intra-oral examination showed multiple caries with pulp involvement.The treatment plan was mouth preparation under general anesthesia, consists of scaling, dental restorations, extractions, and topical fluoride application. The patient with cerebral palsy type spastic cannot control the desired movement, has a hyperactive reflex, and often had seizures. These conditions will make the dental treatment being so difficult. Dental trea...

Journal of updates in Pediatric Dentistry, 2021

Background: To reduce the prevalence of dental problems, especially dental caries, the Ministry o... more Background: To reduce the prevalence of dental problems, especially dental caries, the Ministry of Health has launched a "2030 Indonesia Caries-free" program. The program targets the DMF-T of 12-year-old children to be reduced to below 1.26 by 2030. Therefore, it is necessary to design a dental health education program to increase people's motivation to adopt dental health behavior. Motivation is focused because it is an essential factor that supports a person in making decisions and behaving. Aim: This study evaluates the pilot training for trainers using the motivational interviewing method to change dental health behavior. Method: This program is designed using training for trainer methods with prepared participants to educate the community in their area. Participants are trained by a motivational interviewing coach and practice the motivational interviewing skills with a simulated client. This thirty-hour training includes a four-phase structure; lectures, case handling, practicum, and trials. The evaluation is carried out through three out of four-level evaluation methods from Kirkpatrick. Result: Thirty women were recruited for this training. The women are cadres in integrated health service posts. Evaluation of this training revealed that reaction, learning, and behavior level show a good outcome. Conclusion: Despite the limitation of participants' stiffness during skill practice, the trial run of this training program succeeded in producing thirty cadres ready to implement the program in the community.

Indonesian Journal of Applied Sciences (IJAS), Aug 31, 2015

European Journal of Dentistry, Oct 11, 2022

Understanding the fundamental principles of tooth movement could reduce the duration of treatment... more Understanding the fundamental principles of tooth movement could reduce the duration of treatment and achieve a stable outcome, resulting in patient satisfaction. Hyperbaric oxygen therapy was a modality in which a patient inhaled 100% O 2 while subjected to high atmospheric pressure. Hyperbaric oxygen therapy facilitated the supply of oxygen to the human body's organs and tissues and served a variety of applications, including patient care and wound treatment. This review article aimed to describe animal studies of the potential effects of hyperbaric oxygen therapy in orthodontic therapy. It was conducted using a systematic literature review method, including searching PubMed and Google Scholar for publications relevant to the research topics. The search was filtered to include only research on orthodontic treatment and hyperbaric oxygen therapy and was published in any year. Articles that did not specify biological components of orthodontic tooth movement (OTM) were excluded. The Preferred Reporting Items identified the papers for the Systematic Reviews and Meta-Analyses (PRISMA) strategy, which resulted in the selection of 11 publications. Hyperbaric oxygen therapy affected parameters of biomarkers representing the clinical, molecular, and cellular biology of bone formation and resorption in periodontal tissues in responding to orthodontic physical forces, including alkaline phosphatase, collagen synthesis, osteoblast, osteoclast, osteocyte, type I collagen, vascular endothelial growth factor, osteocalcin, fibroblast, matrix metalloproteinase-8, transforming growth factor-β, partial pressure of oxygen, partial pressure of carbon dioxide, trabecular bone density, and tooth mobility. Hyperbaric oxygen therapy induced an inflammatory response to follow OTM events during active orthodontic

Journal of International Dental and Medical Research, Jul 1, 2018

Dental treatment is a situation that can cause stress, and eventually increasing the level of fea... more Dental treatment is a situation that can cause stress, and eventually increasing the level of fear in children. Several communicative, advance and pharmacological interventions have been established to manage dental fear and uncooperative behavior in children, and it is more recommended focusing more on the non-pharmacological intervention. The purpose of this test is to evaluate the film and live modeling effects in reducing dental fear in preschool children. The participants are students of Sekeloa Kindergaten Bandung Indonesia that have never been visit the dentists before. The program consists of five sessions that are divided into two visits, i.e. the visit in classroom and in dental practice room. Assessments before and after the model film simulation and after the treatment testing, each of the children is measured for the DF level using Facial Image Scales. Forty-five children participating in this intervention program. Before the film model simulation there is a balance between the number of children who are afraid and who are not afraid. After the film simulation, the number of children who are afraid is decreased. And so, after the test session, the number is decreasing a lot. The use of modeling video has a beneficial potency for clinical practices in reducing fear.

World Academy of Science, Engineering and Technology, International Journal of Bioengineering and Life Sciences, Dec 12, 2016

International Journal of Oral-Medical Sciences, 2006

Natural product sciences, 2017

− Six dammarane-type triterpenoids, dammar-24-en-3β-ol (1), 3β-epicabraleahydroxy lactone (2), (E... more − Six dammarane-type triterpenoids, dammar-24-en-3β-ol (1), 3β-epicabraleahydroxy lactone (2), (E)-25-hydroperoxydammar-23-en-3β,20-diol (3), dammar-24-en-3β,20-diol (4), 3β-acetyl-20S,24S-epoxy-25-hydroxydammarane (5), and 3β-epiocotillol (6) were isolated from the methanolic extract of the bark of Aglaia elliptica. The chemical structure were identified on the basis of spectroscopic evidence and by comparison with those spectra previously reported. Compounds 1-6 were isolated first time from this plant. Compounds 1-6, along with a known synthetic analog, cabraleone (7) were evaluated their cytotoxic activity against P-388 murine leukimia cells in vitro. Among those compounds 3β-acetyl-20S,24S-epoxy-25-hydroxydammarane (5) showed strongest cytotoxic activity with IC 50 value of 8.02 ± 0.06 μM.

European Journal of Dentistry, Jun 13, 2023

Objective Blind children tend to have poor oral health. Oral health education is needed to reduce... more Objective Blind children tend to have poor oral health. Oral health education is needed to reduce the prevalence of dental caries and periodontal diseases among blind children. The aim of this study was to evaluate the effectiveness of two tooth brushing exercise methods toward blind children's knowledge, attitude, behavior, and oral hygiene. Materials and Methods The purposive sampling technique was used in this study on 80 blind children aged between 7 and 16. Children were divided into two groups of 40 children each. In group I, children received the tooth-brushing exercise through the Braille-verbal method, and group II received the tactile-verbal method. Their knowledge, behavior, and attitude were recorded by a questionnaire, and their oral hygiene was assessed during a personal oral examination. Data were analyzed using Wilcoxon-Mann-Whitney non-parametric test. Results Differences in effectiveness toward knowledge, attitude, and oral hygiene were found between both methods with the following values: p-value ¼ 0.04 (<0.05), 0.04 (<0.05), and 0.0002 (<0.05). No difference in effectiveness toward behavior was found: p-value 0.30 (>0.05). Conclusion The two tooth-brushing methods could change knowledge, attitude, and oral hygiene in blind children. The tactile-verbal method was more effective than the Braille-verbal method in changing blind children's oral hygiene.

Denta, Aug 12, 2021

The leaves of Altingia excelsa were found to strongly inhibit SP-C1 human tongue cancer cell line... more The leaves of Altingia excelsa were found to strongly inhibit SP-C1 human tongue cancer cell lines. This study was focused on identifying the antiproliferative compound found in A. excelsa leaves and assessing its mechanism of action. The active compound was isolated using column chromatography and identified by the spectroscopic method and was also tested for its antiproliferative properties and the cell cycle analysis in SP-C1 cells by flowcytometry analysis. This work resulted in the isolation of a flavonoid, which was identified to be kaempferol and quercetin. The compounds inhibited SP-C1 cell proliferation in a time-and dose-dependent manner with IC50 values of 0.72 µg/mL and 0. 70 µg/mL for the 24 hours treatments, respectively. Furthermore, the flowcytometry analysis suggested that the compounds exerted its anticancer activities by inhibiting cell cycle. These results suggested that compounds found in A. excelsa providies a basis for its potential use in cancer disease management.

Padjajaran Journal of Dentistry, Mar 31, 2014

Introduction: Mouth Nursing caries is a particular form of dental caries in children and infants.... more Introduction: Mouth Nursing caries is a particular form of dental caries in children and infants. Mouth Nursing Caries occurs in children aged of 2-4 years old and attack the primary maxillary anterior teeth, maxillary and mandibular first primary molar and primary canine mandibular. Nursing caries Mouth happens because of the habit of falling asleep while sucking a bottle containing sweet liquids (baby formula) in a prolonged period. This research aimed to determine the number and the prevalence of preschool children suffering from nursing mouth caries at Cimahi. Methods: The research method was descriptive with survey technique. Samples selected by cluster random sampling technique consisted of 13 kindergartens with 315 preschool children as the total sample. Results: The result shows that 234 or 74 preschool children. 3% have nursing mouth caries and the rest of 81 preschool children or 27.5% do not have nursing mouth caries. Conclusion: This research concludes that the prevalence of Nursing Mouth caries in preschool children at Cimahi in 2012 is74.3% or ¾ of the number of samples Examined.

Padjajaran Journal of Dentistry, Mar 31, 2015

Introduction: The habit of brushing teeth before bedtime is very important to keep the teeth and ... more Introduction: The habit of brushing teeth before bedtime is very important to keep the teeth and mouth clean and healthy this can be evaluated from the plaque index. The objective of this study was to analyzed differences of plaque index among children aged 6-12 years old in Panti Sosial Asuhan Anak William Booth and Rumah Perlindungan Sosial Asuhan Anak (RPSAA) Ciumbuleuit Bandung before and after acquiring a habit of brushing their teeth before bedtime. Methods: This study was a quasi-experimental and it was analyzed statistically using the t test. Total subjects of 31 children consist of 22 children in Panti Sosial Asuhan Anak William Booth and 9 children in Rumah Perlindungan Sosial Asuhan Anak (RPSAA) Ciumbuleuit Bandung. Data was obtained through clinical examination with the PHP (Personal Hygiene Performance) plaque index of Podshadley and Haley. Results: The mean plaque index before acquiring a habit of brushing teeth before bedtime is 2.247 and after, is 0.591. Conclusion: There is a difference in plaque index in children aged 6-12 years in Children's Orphanage William Booth and RPSAA Ciumbuleuit Bandung before and after acquiring a habit of brushing before bedtime.

Natural Product Communications, 2014

Production of IL-8 primarily promotes angiogenic responses in cancer cells, which lead to favorab... more Production of IL-8 primarily promotes angiogenic responses in cancer cells, which lead to favorable disease progression. Suppressing this production may, therefore, be a significant therapeutic intervention in targeting tumor angiogenesis. This study aimed to evaluate the reduction effects of xanthones in cancer cell lines. Nine known prenylated xanthones (1-9), isolated from the pericarp of Garcinia mangostana Linn (GML), were tested for their ability to suppress IL-8 (interleukin-8) of the SP-C1 (Supri's Clone 1) tongue cancer cell line. Of these compounds, 8-hydroxycudraxanthone-G (4) suppressed IL-8 within 48 hours. This is the first report of 8-hydroxycudraxanthone G suppressing the production of IL-8 (45% at 15.7 μg/mL in 48 hours). These results suggest that the prolonged suppression of IL-8 production by cancer cell lines is concerned in the anti-cancer activity of 8-hydroxycudraxanthone.

Stomatognatic, Oct 10, 2019

Kanker lidah merupakan penyakit ganas yang umum terjadi di rongga mulut dan hingga saat ini secar... more Kanker lidah merupakan penyakit ganas yang umum terjadi di rongga mulut dan hingga saat ini secara medis berhasil menyembuhkan sehingga sering dirawat kehidupan. Tujuan penelitian adalah untuk mengidentifikasi matabolitas sekunder daun Rasamala, menguji senyawa daun Rasamala terhadap penghambatan pertumbuhan sel SP-C1. Desain laboratorium eksperimental yang benar menggunakan garis sel kanker lidah mulut SP-C1 digunakan. Ekstrak etil asetat dipisahkan metabolit sekundernya dengan berbagai teknik kromatografi berpedoman pada aktivitas antiproliferasi untuk menghasilkan lima senyawa, yaitu asam 3,4-dihidroksi benzoat (1), asam galat (2), dan apigenin (3). Senyawa 1-3 diuji aktivitas antiproliferatifnya terhadap sel kanker lidah SP-C1 dan menunjukkan nilai IC50 masing-masing 100, Â100, dan Â100 µg / mL. Analisis data menggunakan uji ANACOVA, Tukey HSD dengan taraf signifikansi α = 0,05. Kesimpulannya, senyawa dari daun rasamala memiliki aktivitas antikanker yang kuat pada kanker mulut mulut manusia SP-C1 melalui penghambatan prolierasi sel.

Dental Journal: Majalah Kedokteran Gigi, Jun 30, 2018

Background: Autism spectrum disorder (ASD) is a developmental disorder with three main characteri... more Background: Autism spectrum disorder (ASD) is a developmental disorder with three main characteristics: communication disorders, social interaction disorders and repetitive behavior. The main problem faced when treating child patients with this disorder is the difficulty of establishing communication with the result that they are unable to understand instructions. One form of therapy frequently applied in cases of autism is that of applied behavior analysis (ABA). It is easier for children with ASD to absorb information visually. Purpose: The purpose of this study was to evaluate the effectiveness of ABA-based behavior management using visual media in the form of picture cards for oral examination of children with ASD. Methods: The study design was observational descriptive in nature and the sample selection was based on purposive sampling. The study was conducted by observing changes in childrens' behavior during treatment administered four times a month. The subjects were 13 children with ASD who met the study criteria and were receiving treatment for autism at Prananda special school in Bandung. The collated data related to changes in subjects' behavior observed during four meetings assessed on the basis of score 1 confirming compliance with instructions and 0 indicating non-compliance. A Kruskal-Wallis statistical analisysis test was used to analyze the data. Results: The results showed a general increase in the former over the latter initial behavior during treatment. Statistical analysis showed that the coefficient of Kruskal-Wallis was meaningful in terms of statistical significance with a p-value of 26.947 (<0.05). The multiple comparison value for average ranks was 15.68 (SD 18.69). Conclusion: The conclusion of this study is that the application of a behavior management-based analytical methodology is effective in supporting the oral examination of children with ASD.

Dentino Jurnal Kedokteran Gigi, Sep 28, 2018

Background: Tongue cancer is a common neoplasm found in oral cavity. It is characterized by aggre... more Background: Tongue cancer is a common neoplasm found in oral cavity. It is characterized by aggressive cell growth, poor prognosis and being the cause of mortality. Objectives: to discover bioactive compounds of Rasamala leaves which possess an activity to inhibit SP-C1 human tongue cancer cell proliferation by reducing the expression of c-Myc proto oncogene. Methods: This is an experimental laboratory study using SP-C1 human tongue cancer cell. Separation of bioactive compounds from Rasamala leaves ethyl acetate extract was using various chromatography techniques guided by antiproliferative assay. Results: Two compounds were produced consisting of kaempferol (1) and quercetin (2). Compound 1 and 2 were tested to assess antiproliferative activity of kaempferol and quercetin upon SP-C1tongue cancer cell. IC 50 values obtained from antiproliferative assay of each compound were 0.72 and 0.70 ug/ml respectively. Data analysis using ANCOVA test attained a significant value of α=0.05 and proceeded for probit analysis. The activity of compound 1 and 2 was tested on c-Myc proto oncogene and it was acquired that compound 1 and 2 can suppress c-myc proto oncogene expression. Conclusion: Rasamala compounds consist of kaempferol (1) and quercetin (2) which possess an activity as tongue cancer cell proliferation inhibitor by reducing c-myc proto oncogene expression.