TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions (original) (raw)
Voets T et al (2004) TRPM6 forms the Mg2+influx channel involved in intestinal and renal Mg2+ absorption. J Biol Chem 279(1):19–25 ArticleCASPubMed Google Scholar
Li M, Jiang J, Yue L (2006) Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7. J Gen Physiol 127(5):525–537 ArticleCASPubMed CentralPubMed Google Scholar
Schlingmann KP et al (2002) Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family. Nat Genet 31(2):166–170 ArticleCASPubMed Google Scholar
Walder RY et al (2002) Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia. Nat Genet 31(2):171–174 ArticleCASPubMed Google Scholar
Jin J et al (2008) Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. Science 322(5902):756–760 ArticleCASPubMed CentralPubMed Google Scholar
Woudenberg-Vrenken TE et al (2011) Transient receptor potential melastatin 6 knockout mice are lethal whereas heterozygous deletion results in mild hypomagnesemia. Nephron Physiol 117(2):p11–p19 ArticleCASPubMed Google Scholar
Schmitz C et al (2003) Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7. Cell 114(2):191–200 ArticleCASPubMed Google Scholar
Schmitz C et al (2005) The channel kinases TRPM6 and TRPM7 are functionally nonredundant. J Biol Chem 280(45):37763–37771 ArticleCASPubMed Google Scholar
Ryazanova LV et al (2004) Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel. J Biol Chem 279(5):3708–3716 ArticleCASPubMed Google Scholar
Yamaguchi H et al (2001) Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. Mol Cell 7(5):1047–1057 ArticleCASPubMed Google Scholar
Matsushita M et al (2005) Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. J Biol Chem 280(21):20793–20803 ArticleCASPubMed Google Scholar
Crawley SW, Cote GP (2009) Identification of dimer interactions required for the catalytic activity of the TRPM7 alpha-kinase domain. Biochem J 420(1):115–122 ArticleCASPubMed Google Scholar
Dorovkov MV, Ryazanov AG (2004) Phosphorylation of annexin I by TRPM7 channel-kinase. J Biol Chem 279(49):50643–50646 ArticleCASPubMed Google Scholar
Perraud AL et al (2011) The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k. Cell Signal 23(3):586–593 ArticleCASPubMed CentralPubMed Google Scholar
Deason-Towne F, Perraud AL, Schmitz C (2012) Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C gamma2 (PLCgamma2) using TRPM7-kinase. Cell Signal 24(11):2070–2075 ArticleCASPubMed CentralPubMed Google Scholar
Sahni J, Scharenberg AM (2008) TRPM7 ion channels are required for sustained phosphoinositide 3-kinase signaling in lymphocytes. Cell Metab 8(1):84–93 ArticleCASPubMed CentralPubMed Google Scholar
Wolf FI, Trapani V (2012) Magnesium and its transporters in cancer: a novel paradigm in tumour development. Clin Sci (Lond) 123(7):417–427 ArticleCAS Google Scholar
Middelbeek J et al (2012) TRPM7 is required for breast tumor cell metastasis. Cancer Res 72(16):4250–4261 ArticleCASPubMed Google Scholar
Feske S, Skolnik EY, Prakriya M (2012) Ion channels and transporters in lymphocyte function and immunity. Nat Rev Immunol 12(7):532–547 ArticleCASPubMed CentralPubMed Google Scholar
Desai BN et al (2012) Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis. Dev Cell 22(6):1149–1162 ArticleCASPubMed CentralPubMed Google Scholar
Deason-Towne F, Perraud AL, Schmitz C (2011) The Mg(2+) transporter MagT1 partially rescues cell growth and Mg(2+) uptake in cells lacking the channel-kinase TRPM7. FEBS Lett 585(14):2275–2278 ArticleCASPubMed CentralPubMed Google Scholar
Schneider CA, Rasband WS, Eliceiri KW (2012) NIH image to ImageJ: 25 years of image analysis. Nat Methods 9(7):671–675 ArticleCASPubMed Google Scholar
Clark K et al (2008) Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7. PLoS One 3(3):e1876 ArticlePubMed CentralPubMed Google Scholar
Chubanov V et al (2004) Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia. Proc Natl Acad Sci USA 101(9):2894–2899 ArticleCASPubMed CentralPubMed Google Scholar
Quamme GA (2010) Molecular identification of ancient and modern mammalian magnesium transporters. Am J Physiol Cell Physiol 298(3):C407–C429 ArticleCASPubMed Google Scholar
Chaigne-Delalande B et al (2013) Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D. Science 341(6142):186–191 ArticleCASPubMed CentralPubMed Google Scholar
Hermosura MC et al (2005) A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders. Proc Natl Acad Sci USA 102(32):11510–11515 ArticleCASPubMed CentralPubMed Google Scholar
Zhang Z et al (2014) The TRPM6 kinase domain determines the Mg.ATP sensitivity of TRPM7/M6 heteromeric ion channels. J Biol Chem 289(8):5217–5227 ArticleCASPubMed Google Scholar
Strubing C et al (2001) TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Neuron 29(3):645–655 ArticleCASPubMed Google Scholar
Hofmann T et al (2002) Subunit composition of mammalian transient receptor potential channels in living cells. Proc Natl Acad Sci USA 99(11):7461–7466 ArticleCASPubMed CentralPubMed Google Scholar
Mace KE et al (2010) TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling. J Cell Physiol 225(2):444–453 ArticleCASPubMed Google Scholar
Montell C (2005) The TRP superfamily of cation channels. Sci STKE 2005(272):re3 PubMed Google Scholar
Venkatachalam K, Hofmann T, Montell C (2006) Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1. J Biol Chem 281(25):17517–17527 ArticleCASPubMed CentralPubMed Google Scholar
Dai Q et al (2007) The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. Am J Clin Nutr 86(3):743–751 CASPubMed CentralPubMed Google Scholar
Beech DJ (2012) Integration of transient receptor potential canonical channels with lipids. Acta Physiol (Oxf) 204(2):227–237 ArticleCAS Google Scholar
Toro CA, Arias LA, Brauchi S (2011) Sub-cellular distribution and translocation of TRP channels. Curr Pharm Biotechnol 12(1):12–23 ArticleCASPubMed Google Scholar
Cayouette S, Boulay G (2007) Intracellular trafficking of TRP channels. Cell Calcium 42(2):225–232 ArticleCASPubMed Google Scholar
Nadler MJ et al (2001) LTRPC7 is a Mg. ATP-regulated divalent cation channel required for cell viability. Nature 411(6837):590–595 ArticleCASPubMed Google Scholar
Su LT et al (2006) TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain. J Biol Chem 281(16):11260–11270 ArticleCASPubMed CentralPubMed Google Scholar
Su LT et al (2010) TRPM7 activates m-calpain by stress-dependent stimulation of p38 MAPK and c-Jun N-terminal kinase. J Mol Biol 396(4):858–869 ArticleCASPubMed CentralPubMed Google Scholar