Shifts in the gut microbiota of mice in response to dexamethasone administration (original) (raw)

References

• Abad V, Chrousos GP, Reynolds JC, Nieman LK, Hill SC, Weinstein RS, Leong GM (2001) Glucocorticoid excess during adolescence leads to a major persistent deficit in bone mass and an increase in central body fat. J Bone Miner Res 16(10):1879–1885. https://doi.org/10.1359/jbmr.2001.16.10.1879
  Article CAS PubMed Google Scholar
• Amini-Khoei H, Haghani-Samani E, Beigi M, Soltani A, Mobini G, Dehkordi S, Mirzaian A, Kopaei M, Alizadeh A, Hojjati M, Validi M (2019) On the role of corticosterone in behavioral disorders, microbiota composition alteration and neuroimmune response in adult male mice subjected to maternal separation stress. Int Immunopharmacol 66:242–250. https://doi.org/10.1016/j.intimp.2018.11.037
  Article CAS PubMed Google Scholar
• Aoki M, Shimozuru M, Kikusul T, Takeuchi Y, Mori Y (2010) Sex differences in behavioral and corticosterone responses to mild stressed in ICR mice are altered by ovariectomy in peripubertal period. Zool Sci 27:783–789. https://doi.org/10.2108/zsj.27.783
  Article CAS Google Scholar
• Chen L, Hu C, Lok-Shun Lai N, Zhang W, Hua J, Lam Paul KS, Lam James CW, Zhou B (2018) Acute exposure to PBDEs at an environmentally realistic concentration causes abrupt changes in the gut microbiota and host health of zebrafish. Environ Pollut 240:17–26. https://doi.org/10.1016/j.envpol.2018.04.062
  Article CAS PubMed Google Scholar
• Chen HW, New PK, Yang Y, Rosen CE, Bielecka AA, Kuchroo M, Cline GW, Kruse AC, Ring AM, Crawford JM, Palm NW (2019) A forward chemical genetic screen reveals gut microbiota metabolites that modulate host physiology. Cell 177(5):1217–1231.e18. https://doi.org/10.1016/j.cell.2019.03.036
  Article CAS PubMed PubMed Central Google Scholar
• Claesson MJ, Jeffery IB, Conde S, Power SE, Conner EM, Cusack S, Harris HMB, Coakley M, Lashminarayanan B, Sullivan O, Fitzgerald GF, Deane J, Connor M, Harnedy N, Connor K, Mahony D, Sinderen D, Wallace M, Brennan L, Stanton C, MahonyD SD, Wallace M, Brennan L, Stanton C, Marchesi JR, Fitzgerald AP, Shanahan F, Hill C, Ross RP, Toole PW (2012) Gut microbiota composition correlates with diet and health in the elderly. Nature 488:178–184. https://doi.org/10.1038/nature11319
  Article CAS PubMed Google Scholar
• De La Cochetière MF, Durand T, Lalande V, Petit JC, Potel G, Beaugerie L (2008) Effect of antibiotic therapy on human fecal microbiota and the relation to the development of clostridium difficile. Microb Ecol 56(3):395–402. https://doi.org/10.1007/s00248-007-9356-5
  Article CAS Google Scholar
• Duranti S, Ferrario C, van Sinderen D, Ventura M, Turroni F (2017) Obesity and microbiota: an example of an intricate relationship. Genes Nutr 12:18. https://doi.org/10.1186/s12263-017-0566-2
  Article PubMed PubMed Central Google Scholar
• Falony G, Joossens M, Vieira-Silva S, Wang J, Darzi Y, Faust K, Kurilshikov A, Bonder MJ, Valles-Colomer M, Vandeputte D, Tito RY, Chaffron S, Rymenans L, Verspecht C, Sutter LD, Lima-Mendez G, Dhoe K, Jonckheere K, Homola D, Garcia R, Tigchelaar ET, Eeckhaudt L, Fu J, Henckaerts L, Zhernakova A, Wiimenga C, Raes J (2016) Population-level analysis of gut microbiome variation. Science 352(6285):560–564. https://doi.org/10.1126/science.aad3503
  Article CAS PubMed Google Scholar
• Fardet L, Kassar A, Cabane J, Flahault A (2007) Corticosteroid-induced adverse events in adults. Drug Saf 30(10):861–881. https://doi.org/10.2165/00002018-200730100-00005
  Article CAS PubMed Google Scholar
• Feng W, Wang H, Zhang P, Gao C, Tao J, Ge Z, Zhu D, Bi Y (2017) Modulation of gut microbiota contributes to curcumin-mediated attenuation of hepatic steatosis in rats. Biochim Biophys Acta Gen Subj 1861:1801–1812. https://doi.org/10.1016/j.bbagen.2017.03.017
  Article CAS PubMed Google Scholar
• Fitzpatrick LR, Small JS, Zhang G, Jankowsky R (2009) M1658 a novel immunosuppressive drug (4SC-101) improves TNBS-induced colitis in mice. Gastroenterology 136(5):A-404. https://doi.org/10.1016/S0016-5085(09)61857-6
  Article Google Scholar
• Haro C, Oriol AR, Juan FA, Francisco GD, Pablo PM, Jabier DL, Gracia MQ, Blanca BL, Juan AN, Manuel TS, Jose CC, Jose LM, Francisco PJ, Antonio C (2016) Intestinal microbiota is influenced by gender and body mass index. PLoS One 11(5):e0154090. https://doi.org/10.1371/journal.pone.0154090
  Article CAS PubMed PubMed Central Google Scholar
• Jahng JW, Kim NY, Ryu V, Yoo SB, Kim BT, Kang DW, Lee JH (2008) Dexamethasone reduces food intake, weight gain and the hypothalamic 5-HT concentration and increases plasma leptin in rats. Eur J Pharmacol 581(1–2):64–70. https://doi.org/10.1016/j.ejphar.2007.11.029
  Article CAS PubMed Google Scholar
• Kao SC, Pavlakis N, Harvie R, Vardy JL, Boyer MJ, Zandwijk N, Clarke SJ (2010) High blood neutrophil-to-lymphocyte ratio is an indicator of poor prognosis in malignant mesothelioma patients undergoing systemic therapy. Clin Cancer Res 16:5805–5813. https://doi.org/10.1158/1078-0432.CCR-10-2245
  Article CAS PubMed Google Scholar
• Konstantinov SR, Awati AA, Williams BA, Miller BG, Jones P, Stokes CR, Akkermans ADL, Smidt H, Vos WM (2006) Post-natal development of the porcine microbiota composition and activities. Environ Microbiol 8:1191–1199. https://doi.org/10.1111/j.1462-2920.2006.01009.x
  Article CAS PubMed Google Scholar
• Ley RE, Turnbaugh PJ, Klein S, Gordon JI (2006) Microbial ecology: human gut microbes associated with obesity. Nature 444(7122):1022–1023. https://doi.org/10.1038/nature4441022a
  Article CAS PubMed Google Scholar
• Li S, Zhang C, Gu Y, Chen L, Ou SY, Wang Y, Peng XC (2015) Lean rats gained more body weight than obese ones from a high-fibre diet. Br J Nutr 114:1188–1194. https://doi.org/10.1017/S0007114515002858
  Article CAS PubMed Google Scholar
• Li D, Wang P, Wang P, Hu X, Chen F (2016) The gut microbiota: a treasure for human health. Biotechnol Adv 34:1210–1224. https://doi.org/10.1016/j.biotechadv.2016.08.003
  Article PubMed Google Scholar
• Lozupone CA, Stombaugh JI, Gordon JI, Jansson JK, Knight R (2012) Diversity, stability and resilience of the human gut microbiota. Nature 489:220–230. https://doi.org/10.1038/nature11550
  Article CAS PubMed PubMed Central Google Scholar
• Moeser AJ, Ryan KA, Nighot PK, Blikslager AT (2007) Gastrointestinal dysfunction induced by early weaning is attenuated by delayed weaning and mast cell blockade in pigs. Am J Physiol Gastrointest Liver Physiol 293:G413–G421. https://doi.org/10.1152/ajpgi.00304.2006
  Article CAS PubMed Google Scholar
• Morris DJ, Ridlon JM (2017) Glucocorticoids and gut bacteria: “The GALF Hypothesis” in the metagenomic era. Steroids 125:1–13. https://doi.org/10.1016/j.steroids.2017.06.002
  Article CAS PubMed Google Scholar
• Munck A, Anikó N-F-T (1992) The ups and downs of glucocorticoid physiology permissive and suppressive effects revisited. Mol Cell Endocrinol 90(1):C1–C4. https://doi.org/10.1016/0303-7207(92)90091-J
  Article CAS PubMed Google Scholar
• Neish AS (2009) Microbes in gastrointestinal health and disease. Gastroenterology 136:65–80. https://doi.org/10.1053/j.gastro.2008.10.080
  Article PubMed Google Scholar
• Newton R (2014) Anti-inflammatory glucocorticoids: changing concepts. Eur J Pharmacol 724:2321–2236. https://doi.org/10.1016/j.ejphar.2013.05.035
  Article CAS Google Scholar
• Oray M, Abu Samra K, Ebrahimiadib N, Meese H, Foster CD (2016) Long-term side effects of glucocorticoids. Expert Opin Drug Saf 15:457–465. https://doi.org/10.1517/14740338.2016.1140743
  Article CAS PubMed Google Scholar
• Pan F, Zhang L, Li M, Hu Y, Zeng B, Yuan H, Zhao L, Zhang C (2018) Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice. Microbiome 6:54. https://doi.org/10.1186/s40168-018-0440-5
  Article PubMed PubMed Central Google Scholar
• Patane MA, Schubert W, Sanford T, Gee R, Burgos M, Isom WP, Ruiz-Perez B (2013) Evaluation of ocular and general safety following repeated dosing of dexamethasone phosphate delivered by transscleral iontophoresis in rabbits. J Ocul Pharmacol Ther 29:760–769. https://doi.org/10.1089/jop.2012.0175
  Article CAS PubMed Google Scholar
• Peters BA, Dominianni C, Shapiro JA, Church TR, Wu J, Miller G, Yuen E, Freiman H, Lustbader L, Salik J, Friedlander C, Hayes RB, Ahn J (2016) The gut microbiota in conventional and serrated precursors of colorectal cancer. Microbiome 4:69. https://doi.org/10.1186/s40168-016-0218-6
  Article PubMed PubMed Central Google Scholar
• Qin J, Li Y, Cai Z, Li S, Zhu J, Zhang F, Liang S, Zhang W, Guan Y, Shen D, Peng Y, Zhang D, Jie Z, Wu W, Qin Y, Xue W, Li J, Han L, Lu D, Wu P, Dai Y, Sun X, Li Z, Tang A, Zhong S, Li X, Chen W, Xu R, Wang M, Feng Q, Gong M, Yu J, Zhang Y, Zhang M, Hanse T, Sanchez G, Raes J, Falony G, Okuda S, Almeida M, LeChatelier E, Renault P, Pons N, Batto JM, Zhang Z, Chen H, Yang R, Zheng W, Li S, Yang H, Wang J, Ehrlich SD, Nielsen R, Pedersen O, Kristiansen K, Wang J (2012) A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 490:55–60. https://doi.org/10.1038/nature11450
  Article CAS PubMed Google Scholar
• Raberg L, Grahn M, Hasselquist D, Svensson E (1998) On the adaptive significance of stress-induced immunosuppression. Proc Biol Sci 265:1637–1641. https://doi.org/10.1098/rspb.1998.0482
  Article CAS PubMed PubMed Central Google Scholar
• Sekirov I, Russell SL, Antunes LCM, Finlay BB (2010) Gut microbiota in health and disease. Physiol Rev 90(3):859–904. https://doi.org/10.1152/physrev.00045.2009
  Article CAS PubMed Google Scholar
• Sheehan D, Moran C, Shanahan F (2015) The microbiota in inflammatory bowel disease. J Gastroenterol 50(5):495–507. https://doi.org/10.1007/s00535-015-1064-1
  Article CAS PubMed Google Scholar
• Sinha R, Ahn J, Sampson JN, Shi J, Yu G, Xiong X, Hayes RB, Goedert JJ (2016) Fecal microbiota, fecal metabolome, and colorectal cancer interrelations. PLoS One 11:e0152126. https://doi.org/10.1371/journal.pone.0152126
  Article CAS PubMed PubMed Central Google Scholar
• Tsilimigras MC, Gharaibeh RZ, Sioda M, Gray L, Fodor AA, Lyte M (2018) Interactions between stress and sex in microbial responses within the microbiota-gutbrain axis in a mouse model. Psychosom Med 80:361–369. https://doi.org/10.1097/PSY.0000000000000572
  Article PubMed Google Scholar
• Unsal H, Balkaya M, Unsal C, Biyik H, Basbulbul G, Poyrazoglu E (2008) The short-term effects of different doses of dexamethasone on the numbers of some bacteria in the ileum. Dig Dis Sci 53:1842–1845. https://doi.org/10.1007/s10620-007-0089-6
  Article CAS PubMed Google Scholar
• Wang J, Tang H, Wang X, Zhang X, Zhang C, Zhang M, Zhao Y, Zhao L, Shen J (2016) The structural alteration of gut microbiota in low-birth-weight mice undergoing accelerated postnatal growth. Sci Rep 6:27780. https://doi.org/10.1038/srep27780
  Article CAS PubMed PubMed Central Google Scholar
• Wang Y, Wang B, Wu J, Jiang XY, Tang H, Nielsen OH (2017) Modulation of gut microbiota in pathological states. Engineering 3:83–89. https://doi.org/10.1016/J.ENG.2017.01.013
  Article Google Scholar
• Yang J, Summanen PH, Henning SM, Hsu M, Lam H, Huang J, Tseng C, Dowd SE, Finegold SM, Heber D, Li Z (2015) Xylooligosaccharide supplementation alters gut bacteria in both healthy and prediabetic adults: a pilot study. Front Physiol 6:216. https://doi.org/10.3389/fphys.2015.00216
  Article PubMed PubMed Central Google Scholar
• Zackular JP, Rogers MA, Ruffin MT, Schloss D (2014) The human gut microbiome as a screening tool for colorectal cancer. Cancer Prev Res (Phila) 7:1112–1121. https://doi.org/10.1158/1940-6207.CAPR-14-0129
  Article CAS Google Scholar
• Zhernakova A, Kurilshikov A, Bonder MJ, Tigchelaar EF, Schirmer M, Vatanen T, Mujagic Z, Vila AV, Falony G, Vieira-Silva S, Wang J, Imhann F, Brandsma E, Jankipersadsing SA, Joossens M, Cenit MC, Deelen P, Swertz MA, Weersma RK, Feskens EJM, Netea MG, Gevers D, Jonkers D, Franke L, Aulchenko YS, Huttenhower C, Raes J, Hofker MH, Xavier RJ, Wijmenga C, Fu JY (2016) Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity. Science 352(6285):565–569. https://doi.org/10.1126/science.aad3369
  Article CAS PubMed PubMed Central Google Scholar
• Zuo K, Li J, Xu Q, Hu C, Gao Y, Chen M, Hu R, Liu Y, Chi H, Yin Q, Cao Y, Wang P, Qin Y, Liu X, Zhong J, Cai J, Li K, Yang X (2019) Dysbiotic gut microbes may contribute to hypertension by limiting vitamin D production. Clin Cardiol 42:710–719. https://doi.org/10.1002/clc.23195
  Article PubMed PubMed Central Google Scholar

Download references