Classification of orthostatic intolerance through data analytics (original) (raw)

References

1. Bartoletti A, Alboni P, Ammirati F, Brignole M, Del Rosso A, Manzillo G, Menozzi C, Raviele A, Sutton R (2000) The Italian protocol: a simplified head-up tilt testing potentiated with oral nitroglycerin to assess patients with unexplained syncope. Europace 2(4):339–342
   Article CAS PubMed Google Scholar
2. Breiman L (2001) Random forests. Mach Learn 45:5–32
   Article Google Scholar
3. Brennan M, Palaniswami M, Kamen P (2001) Do existing measures of poincaré plot geometry reflect nonlinear features of heart rate variability? Cureus 48(11):1342–1347
   CAS Google Scholar
4. Brignole M (2007) Diagnosis and treatment of syncope. Heart 93(1):130–136
   Article PubMed PubMed Central Google Scholar
5. Brignole M, Alboni P, Benditt D, Bergfeldt L, Blanc JJ, Thomsen PB, van Dijk J, Fitzpatrick A, Hohnloser S, Janousek J, Kapoor W, Kenny R, Kulakowski P, Masotti G, Moya A, Raviele A, Sutton R, Theodorakis G, Ungar A, Wieling W (2004) Guidelines on management (diagnosis and treatment) of syncope. Eurospace 6(6):467–573
   Article Google Scholar
6. Brignole M, Moya A, de Lange F, Deharoa JC, Elliott M, Fanciulli A, Federowski A, Furlan R, Kenny R, Martin A, Probst V, Reed M, Rice C, Sutton R, Ungar A, van Dijk J (2018) 2018 ESC guidelines for the diagnosis and management of syncope. Eur Heart J 39(21):1883–1948
   Article PubMed Google Scholar
7. Brignole M, Ungar A, Casagranda I, Gulizia M, Lunati M, Ammirati F, Del Rosso A, Sasdelli M, Santini M, Maggi R, Vitale E, Morrione A, Francese G, Vecchi M, Giada F (2010) Syncope Unit (SUP) investigators: prospective multicentre systematic guideline-based management of patients referred to the syncope units of general hospitals. Europace 12(1):109–118
   Article PubMed Google Scholar
8. Cubera K, Stryjewski P, Kuczaj A, Nessler J, Nowalany-Kozielska E, Pytko-Polonzyk J (2017) The impact of gender on the frequency of syncope provoking factors and prodromal signs in patients with vasovagal syncope. Przeglad Lekarski 74(4):147–149
   PubMed Google Scholar
9. Ferreira R, da Silva L (2016) The current indication for pacemaker in patients with cardioinhibitory vasovagal syncope. Open Cardiovasc Med J 10:179–187
   Article Google Scholar
10. Fletcher J (2020) What to know about vasovagal syncope. https://www.medicalnewstoday.com/articles/327406
11. Fu Q, Vangundy T, Galbreath M, Shibata S, Jain M, Hastings J, Bhella P, Levine B (2010) Cardiac origins of the postural orthostatic tachycardia syndrome. J Am Coll Cardiol 55(25):2858–2868
    Article PubMed PubMed Central Google Scholar
12. Furlan R, Diedrich A, Rimoldi A, Palazzolo L, Porta C, Diedrich L, Harris P, Sleight P, Biagioni I, Robertson D, Bernardi L (2003) Effects of unilateral and bilateral carotid baroreflex stimulation on cardiac and neural sympathetic discharge oscillatory patterns. Circulation 108(6):717–723
    Article PubMed Google Scholar
13. Furlan R, Jacob G, Snell M, Robertson D, Porta A, Parris P, Mosqueda-Garcia R (1998) Chronic orthostatic intolerance: a disorder with discordant cardiac and vascular sympathetic control. Circulation 98(20):2154–2159
    Article CAS PubMed Google Scholar
14. Geddes J, Mehlsen J, Olufsen M (2020) Characterization of blood pressure and heart rate oscillations in pots patients via uniform phase empirical mode decomposition. IEEE Trans Biomed Eng 67(11):3016–3025
    Article PubMed Google Scholar
15. Greve Y, Geier F, Popp S, Bertsch T, Singler K, Meier F, Smolarsky A, Mang H, Müller C, Christ M (2014) The prevalence and prognostic significance of near syncope and syncope: a prospective study of 395 cases in an emergency department (the speed study). Dtsch Arztebl Int 111(12):197–204
    PubMed PubMed Central Google Scholar
16. Guyton A, Hall J (2016) Medical physiology, 13th edn. Elsevier, Philadelphia
    Google Scholar
17. Hastie T, Tibshirani R, Friedman J (2009) The elements of statistical learning. Springer Series in Statistics. Springer, New York
    Google Scholar
18. Jacob G, Barbic F, Glago M, Dipaola F, Porta A, Furlan R (2018) Cardiovascular autonomic profile in women with constitutional hypotension. J Hypertens 36(10):2068–2076
    Article CAS PubMed Google Scholar
19. Khodor N (2014) Dynamical analysis of mutivariate time series for the early detection of syncope during head-up tilt test. Ph.D. thesis, Université Rennes 1, Rennes, France
20. Khodor N, Carrault G, Matelot D, Amoud H, Khalil M, Boullay N, Carré F, Hernandez A (2016) Early syncope detection during head up tilt test by analyzing interactions between cardio-vascular signals. Dig Signal Process 49:86–94
    Article Google Scholar
21. Klemenc M, Strumbelj E (2015) Predicting the outcome of head-up tilt test using heart rate variability and baroreflex sensitivity parameters in patients with vasovagal syncope. Clinical Autonomic Res 25 (6):391–398
    Article Google Scholar
22. Kuran A, Erickson M, Petersen M, Franzen A, Williams T, Sutton R (2000) Respiratory changes in vasovagal syncope. J Cardiovasc Electrophysiol 11(6):607–611
    Article Google Scholar
23. Kurbaan A, Bowker T, Wijesekera N, Heaven D, Itty S, Sutton R (2003) Age and hemodynamic responses to tilt testing in those with syncope of unknown origin. J Am Coll Cardiol 41(6):1004–1007
    Article PubMed Google Scholar
24. Li H, Liao Y, Han Z, Wang Y, Liu P, Zhang C, Tang C, Du J, Jin H (2018) Head-up tilt test provokes dynamic alterations in total peripheral resistance and cardiac output in children with vasovagal syncope. Acta Paediatr 107(10):1786–1791
    Article PubMed Google Scholar
25. Mark A (1983) The bezold-jarisch reflex revisited: clinical implications of inhibitory reflexes originating in the heart. JAJCC 1(1):69–72
    Google Scholar
26. Mehlsen J, Kaijer M, Mehlsen AB (2008) Autonomic and electrocardiographic changes in cardioinhibitory syncope. Europace 10(1):91–95
    Article PubMed Google Scholar
27. Moya A, Sutton R, Ammirati F, Blanc JJ, Brignole M, Dahm J, Deharo JC, Gajek J, Gjesdal K, Krahn A, Massin M, Pepi M, Pezawas T, Ruiz Granell R, Sarasin F, Ungar A, van Dijk J, Walma E, Wieling W (2009) Guidelines for the diagnosis and management of syncope (version 2009). Europ Heart J 30:2631–2671
    Article Google Scholar
28. Ocon A, Medow M, Taneja I, Stewart J (2011) Respiration drives phase synchronization between blood pressure and rr interval following loss of cardiovagal baroreflex during vasovagal syncope. Am J Physiol 300(2):H527–H540
    CAS Google Scholar
29. Parati G, Bretinieri M, Pomidossi G, Casadei R, Groppeli A, Pedotti A, Zanchetti A, Mancia G (1988) Evaluation of the baroreceptor-heart rate reflex by 24-hour intra-arterial blood pressure monitoring in humans. Hypertension 12(2):214– 222
    Article CAS PubMed Google Scholar
30. Parlow J, Viale J, Annat G, Hughson R, Quintin L (1995) Spontaneous cardiac baroreflex in humans: comparison with drug-induced responses. Hypertension 25(5):1058–1068
    Article CAS PubMed Google Scholar
31. Probst M, Kanzaria H, Gbedemah M, Richardson L, Sun B (2015) National trends in resource utilization associated with ed visits for syncope. American. J Emergency Med 33(8):998–1001
    Google Scholar
32. Randall E, Billeschou A, Brinth L, Mehlsen J, Olufsen M (2019) A model-based analysis of autonomic nervous function in response to the valsalva maneuver. J Appl Physiol 127(5):1386– 1402
    Article PubMed Google Scholar
33. Randall E, Randolph N, Olufsen M (2020) Persistent instability in a nonhomogeneous delay differential equation system of the valsalva maneuver. Math Biosci 319:108292
    Article PubMed Google Scholar
34. Remmen J, Aengevaeren W, Verheugt F, van ver Werf T, Luijten H, A Bos RJ (2002) Finapres arterial pulse wave analysis with modelflow is not a reliable non-invasive method for assessment of cardiac output. Clin Sci (Lond) 103(2):143–149
    Article Google Scholar
35. Robertson D, Biaggioni I, Low P (2011) Primer on the autonomic nervous system, 3rd edn. Elsevier, London
    Google Scholar
36. Romme J, van Dijk N, Boer K, Dekker L, Stam J, Reitsma J, Wieling W (2008) Influence of age and gender on the occurrence and presentation of reflex syncope. Clin Autonom Res 28(3):127–133
    Article Google Scholar
37. Rousseeuw P (1987) Silhouettes: a graphical aid to the interpretation and validation of cluster analysis. J Comp Appl Math 20:53–65
    Article Google Scholar
38. Sander-Jensen K, Mehlsen J, Stadeager C, Christensen N, Fahrenkrug J, Schwartz T, Warberg J, Bie P (1988) Increase in vagal activity during hypotensive lower-body negative pressure in humans. Am J Physiol 255(1 Pt 2):R149–R156
    CAS PubMed Google Scholar
39. Sheldon R, Grubb B, Olshansky B (2015) 2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope. Heart Rhythm 12(6):e41–e63
    Article PubMed PubMed Central Google Scholar
40. van Dijk J, Thijs R, Benditt D, Wieling W (2009) A guide to disorders causing transient loss of consciousness: focus on syncope. Nat Rev Neurol 5(8):438–448
    Article PubMed Google Scholar
41. Virag N, Sutton R, Vetter R, Markowitz T (2007) Prediction of vasovagal syncope from heart rate and blood pressure trend and variability: experience in 1,155 patients. Heart Rhythm 4(11):1375–1382
    Article PubMed Google Scholar
42. Vlasta B, Marchi A, De Maria B, Rossato G, Nollo G, Faes L, Porta A (2016) Nonlinear effects of respiration on the crosstalk between cardiovascular and cerebrovascular systems. Philos Trans A Math Phys Eng Sci 374(2067):2015079
    Google Scholar
43. Williams N, Wind-Willassen O, Wright A, Program R, Mehlsen J, Ottesen J, Olufsen M (2014) Patient-specific modelling of head-up tilt. Math Med Biol 31(4):365–392
    Article PubMed Google Scholar

Download references