Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity (original) (raw)

• Akira, S. & Takeda, K. Toll-like receptor signalling. Nature Rev. Immunol. 4, 499–511 (2004)
  Article CAS Google Scholar
• Gordon, S. Pattern recognition receptors: doubling up for the innate immune response. Cell 111, 927–930 (2002)
  Article CAS Google Scholar
• Inohara, N. & Nunez, G. NODs: intracellular proteins involved in inflammation and apoptosis. Nature Rev. Immunol. 3, 371–382 (2003)
  Article CAS Google Scholar
• Lin, X. & Wang, D. The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling. Semin. Immunol. 16, 429–435 (2004)
  Article CAS Google Scholar
• Bonizzi, G. & Karin, M. The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 25, 280–288 (2004)
  Article CAS Google Scholar
• Thome, M. CARMA1, BCL-10 and MALT1 in lymphocyte development and activation. Nature Rev. Immunol. 4, 348–359 (2004)
  Article CAS Google Scholar
• Bertin, J. et al. CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-κB. J. Biol. Chem. 275, 41082–41086 (2000)
  Article CAS Google Scholar
• Matsumoto, R. et al. Phosphorylation of CARMA1 plays a critical role in T Cell receptor-mediated NF-κB activation. Immunity 23, 575–585 (2005)
  Article CAS Google Scholar
• Sommer, K. et al. Phosphorylation of the CARMA1 linker controls NF-κB activation. Immunity 23, 561–574 (2005)
  Article CAS Google Scholar
• Thome, M. & Tschopp, J. TCR-induced NF-κB activation: a crucial role for Carma1, Bcl10 and MALT1. Trends Immunol. 24, 419–424 (2003)
  Article CAS Google Scholar
• Di Carlo, F. J. & Fiore, J. V. On the composition of zymosan. Science 127, 756–757 (1958)
  Article ADS CAS Google Scholar
• Brown, G. D. & Gordon, S. Immune recognition. A new receptor for β-glucans. Nature 413, 36–37 (2001)
  Article ADS CAS Google Scholar
• Underhill, D. M. et al. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 401, 811–815 (1999)
  Article ADS CAS Google Scholar
• Brown, G. D. & Gordon, S. Fungal β-glucans and mammalian immunity. Immunity 19, 311–315 (2003)
  Article CAS Google Scholar
• Villamon, E. et al. Toll-like receptor-2 is essential in murine defenses against Candida albicans infections. Microbes Infect. 6, 1–7 (2004)
  Article CAS Google Scholar
• Gantner, B. N., Simmons, R. M., Canavera, S. J., Akira, S. & Underhill, D. M. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J. Exp. Med. 197, 1107–1117 (2003)
  Article CAS PubMed Central Google Scholar
• Rogers, N. C. et al. Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity 22, 507–517 (2005)
  Article CAS Google Scholar
• Brown, G. D. et al. Dectin-1 mediates the biological effects of β-glucans. J. Exp. Med. 197, 1119–1124 (2003)
  Article CAS PubMed Central Google Scholar
• Brown, G. D. Dectin-1: a signalling non-TLR pattern-recognition receptor. Nature Rev. Immunol. 6, 33–43 (2005)
  Article Google Scholar
• Takeuchi, O. et al. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11, 443–451 (1999)
  Article CAS Google Scholar
• Aliprantis, A. O. et al. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 285, 736–739 (1999)
  Article CAS Google Scholar
• Takeuchi, O., Hoshino, K. & Akira, S. Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection. J. Immunol. 165, 5392–5396 (2000)
  Article CAS Google Scholar
• Kawai, T., Adachi, O., Ogawa, T., Takeda, K. & Akira, S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11, 115–122 (1999)
  Article CAS PubMed Central Google Scholar
• Ruland, J. et al. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-κB and neural tube closure. Cell 104, 33–42 (2001)
  Article CAS Google Scholar
• McAllister-Lucas, L. M. et al. Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-κB induction. J. Biol. Chem. 276, 30589–30597 (2001)
  Article CAS Google Scholar
• Eliopoulos, A. G., Das, S. & Tsichlis, P. N. The tyrosine kinase Syk regulates TPL2 activation signals. J. Biol. Chem. 281, 1371–1380 (2006)
  Article CAS Google Scholar
• Ruland, J., Duncan, G. S., Wakeham, A. & Mak, T. W. Differential requirement for Malt1 in T and B cell antigen receptor signaling. Immunity 19, 749–758 (2003)
  Article CAS Google Scholar
• Klemm, S. et al. The Bcl10-Malt1 complex segregates FcɛRI-mediated nuclear factor κB activation and cytokine production from mast cell degranulation. J. Exp. Med. 203, 337–347 (2006)
  Article PubMed Central Google Scholar
• Hammer, M. et al. Control of dual-specificity phosphatase-1 expression in activated macrophages by IL-10. Eur. J. Immunol. 35, 2991–3001 (2005)
  Article CAS Google Scholar
• Sparwasser, T. et al. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur. J. Immunol. 28, 2045–2054 (1998)
  Article CAS Google Scholar